Amnesia MRI
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Zehra Malik, M.B.B.S[2]
Overview
Head MRI may be helpful in the diagnosis of the cause of amnesia in some cases including, Alzheimer's disease, or brain trauma. In majority of the cases of amnesia the brain appears normal on MRI.
MRI
- Psychogenic amnesia is defined by the lack of structural damage to the brain, but upon functional imaging, abnormal brain activity can be seen. Tests using functional magnetic resonance imaging suggest that patients with psychogenic amnesia are unable to retrieve emotional memories normally during the amnesic period, suggesting that changes in the limbic functions are related to the symptoms of psychogenic amnesia.[1]
- In transient epileptic amnesia MRI is usually normal. However, in some patients frontal and temporal lobe abnormalities have been observed.[2]
- Brain MRI findings suggestive of Alzheimer's disease include, reduction in hippocampal volume and atrophy of medial temporal lobe [3] [4] [5]
References
- ↑ Yang JC, Jeong GW, Lee MS; et al. (2005). "Functional MR imaging of psychogenic amnesia: a case report". Korean J Radiol. 6 (3): 196–9. PMID 16145296.
- ↑ Ramanan VK, Morris KA, Graff-Radford J, Jones DT, Burkholder DB, Britton JW; et al. (2019). "Transient Epileptic Amnesia: A Treatable Cause of Spells Associated With Persistent Cognitive Symptoms". Front Neurol. 10: 939. doi:10.3389/fneur.2019.00939. PMC 6724577 Check
|pmc=value (help). PMID 31555199. - ↑ Whitwell JL, Dickson DW, Murray ME, Weigand SD, Tosakulwong N, Senjem ML; et al. (2012). "Neuroimaging correlates of pathologically defined subtypes of Alzheimer's disease: a case-control study". Lancet Neurol. 11 (10): 868–77. doi:10.1016/S1474-4422(12)70200-4. PMC 3490201. PMID 22951070.
- ↑ Brook RH (1992). "Improving practice: the clinician's role". Br J Surg. 79 (7): 606–7. PMID 1643466.
- ↑ Barkhof F, Polvikoski TM, van Straaten EC, Kalaria RN, Sulkava R, Aronen HJ; et al. (2007). "The significance of medial temporal lobe atrophy: a postmortem MRI study in the very old". Neurology. 69 (15): 1521–7. doi:10.1212/01.wnl.0000277459.83543.99. PMID 17923614.