Alpha 1-antitrypsin deficiency MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mazia Fatima, MBBS [2]

Overview

MRI is not indicated in the diagnosis of alpha 1-antitrypsin deficiency. There are no specific MRI findings associated with alpha 1-antitrypsin deficiency.

MRI

  • MRI is not indicated in the diagnosis of alpha 1-antitrypsin deficiency. There are no specific MRI findings associated with alpha 1-antitrypsin deficiency.[1]
  • Standard MRI techniques receive poor signal as a result of low proton density of lung parenchyma.
  • Findings on MRI of alpha 1-antitrypsin deficiency suggest emphysematous changes with lower lobe predominance.

References

  1. Kauczor HU, Kreitner KF (1999). "MRI of the pulmonary parenchyma". Eur Radiol. 9 (9): 1755–64. doi:10.1007/s003300050919. PMID 10602947.



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