4-HO-DET

4-HO-DET

File:4-HO-DET.svg
File:4-HO-DET-3d-sticks.png
Gene therapy
Clinical data
Physiological data
Legal status
Pharmacokinetic data
Identifiers
IUPAC name 3-(2-diethylaminoethyl)-1H-indol-4-ol
CAS Number	22204-89-3
Chemical and physical data
Formula	C14H20N2O
Molar mass	232.32 g/mol
3D model (JSmol)	Interactive image
SMILES CCN(CC)CCC1=CNC2=C1C(O)=CC=C2

4-HO-DET, also known as 4-hydroxy-diethyl-tryptamine, CZ-74, or ethocin, is a hallucinogenic drug and psychedelic compound of moderate duration. 4-HO-DET is a substituted tryptamine, structurally related to psilocin and 4-HO-DIPT.

Analogs

The acetic acid ester of 4-HO-DET is known as 4-AcO-DET or ethacetin. The phosphoric acid ester of 4-HO-DET is known as 4-phosphoryloxy-DET, CEY-19, or ethocybin.

History

4-HO-DET received the lab code CZ-74 in the late 1950s by the inventors of the substance, Albert Hofmann and Franz Troxler. The substance was used together with its phosporyloxy-analog CEY-19 in human clinical trials in the 1960s by the German researchers Hanscarl Leuner and G. Baer.

Dosage

10-25mg is the usual oral dosage for 4-HO-DET, while the acetate and phosphate esters are said to require a slightly higher dosage.

Effects

Ethocin produces entheogenic effects similar to LSD and psilocybin. Some users have reported unpleasant anxiety and stimulation with this drug, while other accounts label the experience as being much milder than LSD or psilocybin.

See also

• TiHKAL
• Indoles

External links

• TiHKAL 4-HO-DET information at Erowid
• Ethacetin degradation by Murple