TIMI flow grade 0

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The TIMI flow grading system is a widely used method of grading coronary flow.[1] While the TMPG that was invented by C. Michael Gibson M.S., M.D.[2]assesses perfusion in the capillary bed at the tissue level, the TIMI flow grade is used to assess epicardial coronary blood flow.

Definition

No perfusion. No antegrade flow beyond the point of occlusion.[3] [4] [5]

TIMI Frame Count in the Setting of TIMI Flow Grade 1

In the case of a TIMI Flow Grade 0, 1, or 1.5 there is no measurable TIMI Frame Count; therefore, DNA (Does Not Apply) is recorded on the case report form in the TIMI Frame Count field.

References

  1. "The Thrombolysis in Myocardial Infarction (TIMI... [N Engl J Med. 1985] - PubMed - NCBI". Retrieved 29 August 2013.
  2. Gibson CM, Cannon CP, Murphy SA, Ryan KA, Mesley R, Marble SJ; et al. (2000). "Relationship of TIMI myocardial perfusion grade to mortality after administration of thrombolytic drugs". Circulation. 101 (2): 125–30. PMID 10637197.
  3. Gibson, CM; Ryan, K; Sparano, A; Rizzo, M; Moynihan, J; Kelley, M; Marble, SJ; Dodge, JT; Antman, EM. Methodologic drift in the assessment of TIMI grade 3 flow and its implications with respect to the reporting of angiographic trial results. Am Heart J. 1999;137:1179–1184. PMID 10347349
  4. Gibson CM, Cannon CP, Daley WL, Dodge JT Jr, Alexander B Jr, Marble SJ, McCabe CH, Raymond L, Fortin T, Poole WK, Braunwald E. TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation. 1996 Mar 1;93(5):879-88. PMID 8598078
  5. Gibson CM, Murphy S, Menown IB, Sequeira RF, Greene R, Van de Werf F, Schweiger MJ, Ghali M, Frey MJ, Ryan KA, Marble SJ, Giugliano RP, Antman EM, Cannon CP, Braunwald E. Determinants of coronary blood flow after thrombolytic administration. TIMI Study Group. Thrombolysis in Myocardial Infarction. J Am Coll Cardiol. 1999 Nov 1;34(5):1403-12. PMID 10551685


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