Squamous cell carcinoma of the lung other diagnostic studies: Difference between revisions
Shanshan Cen (talk | contribs) (Created page with "__NOTOC__ {{Squamous cell carcinoma of the lung}} {{CMG}}; {{AE}} {{SC}} ==References== {{reflist|2}} {{WikiDoc Help Menu}} {{WikiDoc Sources}} Category:Disease Categ...") |
|||
(5 intermediate revisions by 3 users not shown) | |||
Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{Squamous cell carcinoma of the lung}} | {{Squamous cell carcinoma of the lung}} | ||
{{CMG}}; {{AE}} {{ | {{CMG}}; {{AE}} {{MV}} | ||
==Overview== | |||
Other diagnostic modalities for squamous cell carcinoma of the lung, include: thoracotomy, thoracoscopy, bronchoscopy, mediastinoscopy, transthoracic percutaneous [[fine needle aspiration]], and sputum cytology. | |||
==Other Diagnostic Studies== | |||
*Other diagnostic modalities for squamous cell carcinoma of the lung include:<ref name="pmid24484269">{{cite journal |vauthors=Kinsey CM, Arenberg DA |title=Endobronchial ultrasound-guided transbronchial needle aspiration for non-small cell lung cancer staging |journal=Am. J. Respir. Crit. Care Med. |volume=189 |issue=6 |pages=640–9 |year=2014 |pmid=24484269 |doi=10.1164/rccm.201311-2007CI |url=}}</ref> | |||
:*[[Thoracotomy]] | |||
:*[[Thoracoscopy]] | |||
:*[[Bronchoscopy]] for: | |||
::*Bronchial brush | |||
::*Bronchial wash | |||
::*Bronchioloalveolar lavage | |||
::*Transbronchial [[Fine-needle aspiration|fine-needle aspiration (FNA)]] | |||
::*Core biopsy | |||
:*Mediastinoscopy | |||
::*Chamberlain procedure | |||
::*Left parasternal mediastinotomy | |||
::*Anterior mediastinotomy | |||
:*Transthoracic percutaneous [[fine needle aspiration]] | |||
:*Sputum cytology | |||
::*The [[sensitivity]] or sputum cytology varies by location of the lung cancer | |||
*The majority of these procedures allow staging of [[Mediastinal lymph node|mediastinal lymph nodes]]. | |||
*The table below summarizes the different types of diagnostic modalities in non small cell lung cancer arranged from the most to the least invasive.<ref name="pmid17296659">{{cite journal |vauthors=Micames CG, McCrory DC, Pavey DA, Jowell PS, Gress FG |title=Endoscopic ultrasound-guided fine-needle aspiration for non-small cell lung cancer staging: A systematic review and metaanalysis |journal=Chest |volume=131 |issue=2 |pages=539–48|date=February 2007 |pmid=17296659|doi=10.1378/chest.06-1437|url=http://www.chestjournal.org/cgi/content/full/131/2/539}}</ref><ref name="pmid17589301">{{cite journal |vauthors=Kim ES, Bosquée L |title=The importance of accurate lymph node staging in early and locally advanced non-small cell lung cancer: an update on available techniques |journal=J Thorac Oncol |volume=2 Suppl 2 |issue= |pages=S59–67 |date=June 2007 |pmid=17589301 |doi=10.1097/01.JTO.0000269738.13586.fd |url=}}</ref><ref name="Wiersema">Wiersema M et al. Real-time endoscopic ultrasound-guided fine-needle aspiration of a mediastinal lymph node. Gastrointest Endosc 1993, 39(3):429-431</ref><ref name="pmid18252884">{{cite journal |vauthors=Wallace MB, Pascual JM, Raimondo M, etal |title=Minimally invasive endoscopic staging of suspected lung cancer |journal=JAMA |volume=299 |issue=5 |pages=540–6 |date=February 2008 |pmid=18252884 |doi=10.1001/jama.299.5.540 |url=}}</ref><ref name="Singh">Singh P et al. Endoscopic ultrasound as a first test for diagnosis and staging of lung cancer: a prospective study. Am J Respir Crit Care Med 2007, 175(4):345-354.</ref><ref name="Cerfolio">Cerfolio R, Bryant A, Ojha B: Restaging patients with N2 (stage IIIa) non-small cell lung cancer after neoadjuvant chemoradiotherapy: a prospective study. J Thorac Cardiovasc Surg 2006, 131(6):1229-1235</ref><ref name="Yasufuku">Yasufuku K et al. Endobronchial ultrasonography: current status and future directions. J Thorac Oncol 2007, 2(10):970-979.</ref> | |||
{| style="border: 0px; font-size: 90%; margin: 3px; width: 1000px" align="center" | |||
| valign="top" | | |||
|+ | |||
|- | |||
! style="background: #4479BA; width: 300px;" | {{fontcolor|#FFF|Procedure}} | |||
! style="background: #4479BA; width: 300px;" | {{fontcolor|#FFF|Advantages}} | |||
! style="background: #4479BA; width: 300px;" | {{fontcolor|#FFF|Disadvantages}} | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" | [[Thoracotomy]] | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
*Allows the most thorough inspection and sampling of lymph node stations | |||
*May be followed by resection of tumor, if feasible | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
*Invasive approach | |||
*Not indicated for staging alone | |||
*Significant risk of procedure-related morbidity | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" | Anterior Mediastinotomy | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
*Allows evaluation of the aortopulmonary window lymph nodes | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
*More invasive | |||
*False-negative rate approximately 10% | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" | Chamberlain procedure | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
*Access to station 5 ([[aortopulmonary window]] lymph node) | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
*Limited applications, invasive | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" | [[Mediastinoscopy|Cervical mediastinoscopy]] | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
*Considered the gold standard (usual comparitor) | |||
*Excellent for 2RL 4RL | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
*Invasive | |||
*Does not cover all mediastinal lymph node stations; particularly subcarinal lymph nodes (station 7), paraesophageal and pulmonary ligament lymph nodes (stations 8 and 9). | |||
*False-negative rate approximately 20% | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" | [[Thoracoscopy|Video-assisted thoracoscopy]] | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
*Useful for the evaluation of inferior mediastinum, station 5 and 6 lymph nodes | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
*Invasive | |||
*Does not cover superior anterior mediastinum | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" | Transthoracic percutaneous [[fine needle aspiration]] under CT guidance | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
*Widely available than some other methods | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
*Traverses a lot of lung tissue | |||
*High pneumothorax risk | |||
*Some lymph node stations inaccessible | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" | [[Bronchoscopy]] with blind transbronchial Wang needle | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
*Less invasive than above methods | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
*Relatively low yield | |||
*Not widely practiced | |||
*Bleeding risk | |||
|- | |||
|} | |||
==References== | ==References== | ||
Line 14: | Line 104: | ||
[[Category:Lung cancer]] | [[Category:Lung cancer]] | ||
[[Category:Oncology]] | [[Category:Oncology]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Pulmonology]] | |||
[[Category:Surgery]] |
Latest revision as of 19:33, 18 October 2019
Squamous Cell Carcinoma of the Lung Microchapters |
Differentiating Squamous Cell Carcinoma of the Lung from other Diseases |
---|
Diagnosis |
Treatment |
Case Studies |
Squamous cell carcinoma of the lung other diagnostic studies On the Web |
American Roentgen Ray Society Images of Squamous cell carcinoma of the lung other diagnostic studies |
FDA on Squamous cell carcinoma of the lung other diagnostic studies |
CDC on Squamous cell carcinoma of the lung other diagnostic studies |
Squamous cell carcinoma of the lung other diagnostic studies in the news |
Blogs on Squamous cell carcinoma of the lung other diagnostic studies |
Directions to Hospitals Treating Squamous cell carcinoma of the lung |
Risk calculators and risk factors for Squamous cell carcinoma of the lung other diagnostic studies |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Other diagnostic modalities for squamous cell carcinoma of the lung, include: thoracotomy, thoracoscopy, bronchoscopy, mediastinoscopy, transthoracic percutaneous fine needle aspiration, and sputum cytology.
Other Diagnostic Studies
- Other diagnostic modalities for squamous cell carcinoma of the lung include:[1]
-
- Bronchial brush
- Bronchial wash
- Bronchioloalveolar lavage
- Transbronchial fine-needle aspiration (FNA)
- Core biopsy
- Mediastinoscopy
- Chamberlain procedure
- Left parasternal mediastinotomy
- Anterior mediastinotomy
- Transthoracic percutaneous fine needle aspiration
- Sputum cytology
- The sensitivity or sputum cytology varies by location of the lung cancer
- The majority of these procedures allow staging of mediastinal lymph nodes.
- The table below summarizes the different types of diagnostic modalities in non small cell lung cancer arranged from the most to the least invasive.[2][3][4][5][6][7][8]
Procedure | Advantages | Disadvantages |
---|---|---|
Thoracotomy |
|
|
Anterior Mediastinotomy |
|
|
Chamberlain procedure |
|
|
Cervical mediastinoscopy |
|
|
Video-assisted thoracoscopy |
|
|
Transthoracic percutaneous fine needle aspiration under CT guidance |
|
|
Bronchoscopy with blind transbronchial Wang needle |
|
|
References
- ↑ Kinsey CM, Arenberg DA (2014). "Endobronchial ultrasound-guided transbronchial needle aspiration for non-small cell lung cancer staging". Am. J. Respir. Crit. Care Med. 189 (6): 640–9. doi:10.1164/rccm.201311-2007CI. PMID 24484269.
- ↑ Micames CG, McCrory DC, Pavey DA, Jowell PS, Gress FG (February 2007). "Endoscopic ultrasound-guided fine-needle aspiration for non-small cell lung cancer staging: A systematic review and metaanalysis". Chest. 131 (2): 539–48. doi:10.1378/chest.06-1437. PMID 17296659.
- ↑ Kim ES, Bosquée L (June 2007). "The importance of accurate lymph node staging in early and locally advanced non-small cell lung cancer: an update on available techniques". J Thorac Oncol. 2 Suppl 2: S59–67. doi:10.1097/01.JTO.0000269738.13586.fd. PMID 17589301.
- ↑ Wiersema M et al. Real-time endoscopic ultrasound-guided fine-needle aspiration of a mediastinal lymph node. Gastrointest Endosc 1993, 39(3):429-431
- ↑ Wallace MB, Pascual JM, Raimondo M, et al. (February 2008). "Minimally invasive endoscopic staging of suspected lung cancer". JAMA. 299 (5): 540–6. doi:10.1001/jama.299.5.540. PMID 18252884.
- ↑ Singh P et al. Endoscopic ultrasound as a first test for diagnosis and staging of lung cancer: a prospective study. Am J Respir Crit Care Med 2007, 175(4):345-354.
- ↑ Cerfolio R, Bryant A, Ojha B: Restaging patients with N2 (stage IIIa) non-small cell lung cancer after neoadjuvant chemoradiotherapy: a prospective study. J Thorac Cardiovasc Surg 2006, 131(6):1229-1235
- ↑ Yasufuku K et al. Endobronchial ultrasonography: current status and future directions. J Thorac Oncol 2007, 2(10):970-979.