Molluscum contagiosum differential diagnosis: Difference between revisions

Latest revision as of 22:45, 29 July 2020

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2], João André Alves Silva, M.D. [3]

Overview

Molluscum contagiosum must be differentiated from other diseases that cause inflammatory or ulcertive skin , genital, or mucosal lesions including chicken pox, herpes zoster, erythema multiforme, cryptococcosis, histoplasmosis, pyogenic granuloma.

Differential Diagnosis

Different conditions that cause a round papular rash must be differentiated from molluscum contagiosum based on the appearance of the lesions such as:^[1]^[2]^[3]^[4]^[5]^[6]^[7]

Disease	Features	Images
Molluscum contagiosum	Skin papules: Firm Dome shaped Shiny 2 to 5 mm diameter May have central indentation or umbilication Polypoid lesion: Occasionally, with a stalk-like base Visibly inflamed lesions occasionally may be seen Diffuse erythema: May be seen due to Gianotti-Crosti like eruptions
Cryptococcosis^[8]	Caused by encapsulated yeast (fungus) Cryptococcus neoformans May be completely asymptomatic May have latent infection or symptomatic disease Pneumonia-like illness with fever, cough, sputum production and chest pain May lead to: Meningoencephalitis
Histoplasmosis ^[9]^[10]^[11]^[12]	Acquired via inhalation of airborne microconidia Can present with: Acute pulmonary histoplasmosis presenting with fever, cough and dyspnea Skin rash Symmetrical joint pain Disseminated histoplasmosis presents with: Sepsis Acute respiratory distress syndrome Disseminated intravascular coagulation
Penicillium marneffei^[13]	Fever Skin lesions Anemia Generalized lymphadenopathy Hepatomegaly
Condyloma acuminatum ^[14]	Occur in clusters May be very tiny May spread into large masses in the genital or penis area
Pyogenic granuloma^[15]^[16]^[17]	A vascular lesion occurs on both mucosa and skin Appears as an overgrowth of tissue due to irritation, physical trauma or hormonal factors Involve the gums, the skin and nasal septum, and has also been found far from the head such as in the thigh
Langerhans cell histiocytosis^[18]^[19]^[20]^[21]^[22]	Result of either a true neoplastic process or a reactive immune condition. Common symptoms of Langerhans cell histiocytosis include: Bone pain Rash Fever Failure to thrive Scaly erythematous lesions located on the scalp and extremities Localized bone tenderness Hepatosplenomegaly
Basal cell carcinoma^[23]	Skin growths on sun-exposed skin Ulcerative pupils
Amelanotic melanoma	Amelanotic or hypomelanotic lesions or maybe nodular and desmoplastic subtypes Lesions may present as pink or red macules, plaques, or nodules, often with well-defined borders Often clinically confused with benign lesions

References

↑ Hartman-Adams H, Banvard C, Juckett G (2014). "Impetigo: diagnosis and treatment". Am Fam Physician. 90 (4): 229–35. PMID 25250996.
↑ Mehta N, Chen KK, Kroumpouzos G (2016). "Skin disease in pregnancy: The approach of the obstetric medicine physician". Clin Dermatol. 34 (3): 320–6. doi:10.1016/j.clindermatol.2016.02.003. PMID 27265069.
↑ Moore, Zack S; Seward, Jane F; Lane, J Michael (2006). "Smallpox". The Lancet. 367 (9508): 425–435. doi:10.1016/S0140-6736(06)68143-9. ISSN 0140-6736.
↑ Ibrahim F, Khan T, Pujalte GG (2015). "Bacterial Skin Infections". Prim Care. 42 (4): 485–99. doi:10.1016/j.pop.2015.08.001. PMID 26612370.
↑ Ramoni S, Boneschi V, Cusini M (2016). "Syphilis as "the great imitator": a case of impetiginoid syphiloderm". Int J Dermatol. 55 (3): e162–3. doi:10.1111/ijd.13072. PMID 26566601.
↑ Kimura U, Yokoyama K, Hiruma M, Kano R, Takamori K, Suga Y (2015). "Tinea faciei caused by Trichophyton mentagrophytes (molecular type Arthroderma benhamiae ) mimics impetigo : a case report and literature review of cases in Japan". Med Mycol J. 56 (1): E1–5. doi:10.3314/mmj.56.E1. PMID 25855021.
↑ CEDEF (2012). "[Item 87--Mucocutaneous bacterial infections]". Ann Dermatol Venereol. 139 (11 Suppl): A32–9. doi:10.1016/j.annder.2012.01.002. PMID 23176858.
↑ Miyazato A (2016). "[Mechanism of Cryptococcus Meningoencephalitis]". Med Mycol J (in Japanese). 57 (1): J27–32. doi:10.3314/mmj.57.J27. PMID 26936349.
↑ Knox KS, Hage CA (2010). "Histoplasmosis". Proc Am Thorac Soc. 7 (3): 169–72. doi:10.1513/pats.200907-069AL. PMID 20463244.
↑ Kauffman CA (2009). "Histoplasmosis". Clin Chest Med. 30 (2): 217–25, v. doi:10.1016/j.ccm.2009.02.002. PMID 19375629.
↑ Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, Brun-Buisson C, Beale R, Calandra T, Dhainaut JF, Gerlach H, Harvey M, Marini JJ, Marshall J, Ranieri M, Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL (2008). "Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008". Critical Care Medicine. 36 (1): 296–327. doi:10.1097/01.CCM.0000298158.12101.41. PMID 18158437. Retrieved 2012-09-16. Unknown parameter |month= ignored (help)
↑ Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest. 1992 Jun;101(6):1644-55. PMID 1303622.
↑ Supparatpinyo K, Chiewchanvit S, Hirunsri P, Baosoung V, Uthammachai C, Chaimongkol B; et al. (1992). "An efficacy study of itraconazole in the treatment of Penicillium marneffei infection". J Med Assoc Thai. 75 (12): 688–91. PMID 1339213.
↑ Cortez, Michelle Fay and Pettypiece, Shannon. "Merck Cancer Shot Cuts Genital Warts, Lesions in Men". Bloomberg News. (Bloomberg.com) 13 Nov 2008.
↑ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
↑ Jafarzadeh H, Sanatkhani M, Mohtasham N (December 2006). "Oral pyogenic granuloma: a review" (– ^{Scholar search}). J Oral Sci. 48 (4): 167–75. doi:10.2334/josnusd.48.167. PMID 17220613. Retrieved 2009-01-04.^{[dead link]}
↑ Nthumba PM (2008). "Giant pyogenic granuloma of the thigh: a case report". J Med Case Reports. 2 (1): 95. doi:10.1186/1752-1947-2-95. PMC 2329656. PMID 18377654.
↑ Grana N (2014). "Langerhans cell histiocytosis". Cancer Control. 21 (4): 328–34. PMID 25310214.
↑ Harmon CM, Brown N (2015). "Langerhans Cell Histiocytosis: A Clinicopathologic Review and Molecular Pathogenetic Update". Arch Pathol Lab Med. 139 (10): 1211–4. doi:10.5858/arpa.2015-0199-RA. PMID 26414464.
↑ DiCaprio MR, Roberts TT (2014). "Diagnosis and Management of Langerhans Cell Histiocytosis". J Am Acad Orthop Surg. 22 (10): 643–652. doi:10.5435/JAAOS-22-10-643. PMID 25281259.
↑ Langerhans cell histiocytosis. Wikipedia (2015) https://en.wikipedia.org/wiki/Langerhans_cell_histiocytosis Accessed on February, 2 2016
↑ Langerhans cell histiocytosis. Radiopeadia (2015) http://radiopaedia.org/articles/langerhans-cell-histiocytosis Accessed on February, 3 2016
↑ Epstein EH, Shepard JA, Flotte TJ (2008). "Case records of the Massachusetts General Hospital. Case 3-2008. An 80-year-old woman with cutaneous basal-cell carcinomas and cysts of the jaws". N Engl J Med. 358 (4): 393–401. doi:10.1056/NEJMcpc0707893. PMID 18216361. Unknown parameter |month= ignored (help)

Template:WikiDoc Sources

[pmid25250996-1] Hartman-Adams H, Banvard C, Juckett G (2014). "Impetigo: diagnosis and treatment". Am Fam Physician. 90 (4): 229–35. PMID 25250996.

[pmid27265069-2] Mehta N, Chen KK, Kroumpouzos G (2016). "Skin disease in pregnancy: The approach of the obstetric medicine physician". Clin Dermatol. 34 (3): 320–6. doi:10.1016/j.clindermatol.2016.02.003. PMID 27265069.

[MooreSeward2006-3] Moore, Zack S; Seward, Jane F; Lane, J Michael (2006). "Smallpox". The Lancet. 367 (9508): 425–435. doi:10.1016/S0140-6736(06)68143-9. ISSN 0140-6736.

[pmid26612370-4] Ibrahim F, Khan T, Pujalte GG (2015). "Bacterial Skin Infections". Prim Care. 42 (4): 485–99. doi:10.1016/j.pop.2015.08.001. PMID 26612370.

[pmid26566601-5] Ramoni S, Boneschi V, Cusini M (2016). "Syphilis as "the great imitator": a case of impetiginoid syphiloderm". Int J Dermatol. 55 (3): e162–3. doi:10.1111/ijd.13072. PMID 26566601.

[pmid25855021-6] Kimura U, Yokoyama K, Hiruma M, Kano R, Takamori K, Suga Y (2015). "Tinea faciei caused by Trichophyton mentagrophytes (molecular type Arthroderma benhamiae ) mimics impetigo : a case report and literature review of cases in Japan". Med Mycol J. 56 (1): E1–5. doi:10.3314/mmj.56.E1. PMID 25855021.

[pmid23176858-7] CEDEF (2012). "[Item 87--Mucocutaneous bacterial infections]". Ann Dermatol Venereol. 139 (11 Suppl): A32–9. doi:10.1016/j.annder.2012.01.002. PMID 23176858.

[pmid26936349-8] Miyazato A (2016). "[Mechanism of Cryptococcus Meningoencephalitis]". Med Mycol J (in Japanese). 57 (1): J27–32. doi:10.3314/mmj.57.J27. PMID 26936349.

[pmid20463244-9] Knox KS, Hage CA (2010). "Histoplasmosis". Proc Am Thorac Soc. 7 (3): 169–72. doi:10.1513/pats.200907-069AL. PMID 20463244.

[pmid19375629-10] Kauffman CA (2009). "Histoplasmosis". Clin Chest Med. 30 (2): 217–25, v. doi:10.1016/j.ccm.2009.02.002. PMID 19375629.

[pmid18158437-11] Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, Brun-Buisson C, Beale R, Calandra T, Dhainaut JF, Gerlach H, Harvey M, Marini JJ, Marshall J, Ranieri M, Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL (2008). "Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008". Critical Care Medicine. 36 (1): 296–327. doi:10.1097/01.CCM.0000298158.12101.41. PMID 18158437. Retrieved 2012-09-16. Unknown parameter |month= ignored (help)

[12] Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest. 1992 Jun;101(6):1644-55. PMID 1303622.

[pmid1339213-13] Supparatpinyo K, Chiewchanvit S, Hirunsri P, Baosoung V, Uthammachai C, Chaimongkol B; et al. (1992). "An efficacy study of itraconazole in the treatment of Penicillium marneffei infection". J Med Assoc Thai. 75 (12): 688–91. PMID 1339213.

[Bloomberg-14] Cortez, Michelle Fay and Pettypiece, Shannon. "Merck Cancer Shot Cuts Genital Warts, Lesions in Men". Bloomberg News. (Bloomberg.com) 13 Nov 2008.

[Fitz2-15] Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.

[joralsci-16] Jafarzadeh H, Sanatkhani M, Mohtasham N (December 2006). "Oral pyogenic granuloma: a review" (– ^{Scholar search}). J Oral Sci. 48 (4): 167–75. doi:10.2334/josnusd.48.167. PMID 17220613. Retrieved 2009-01-04.^{[dead link]}

[Nthumba-17] Nthumba PM (2008). "Giant pyogenic granuloma of the thigh: a case report". J Med Case Reports. 2 (1): 95. doi:10.1186/1752-1947-2-95. PMC 2329656. PMID 18377654.

[pmid25310214-18] Grana N (2014). "Langerhans cell histiocytosis". Cancer Control. 21 (4): 328–34. PMID 25310214.

[pmid26414464-19] Harmon CM, Brown N (2015). "Langerhans Cell Histiocytosis: A Clinicopathologic Review and Molecular Pathogenetic Update". Arch Pathol Lab Med. 139 (10): 1211–4. doi:10.5858/arpa.2015-0199-RA. PMID 26414464.

[pmid25281259-20] DiCaprio MR, Roberts TT (2014). "Diagnosis and Management of Langerhans Cell Histiocytosis". J Am Acad Orthop Surg. 22 (10): 643–652. doi:10.5435/JAAOS-22-10-643. PMID 25281259.

[wiki-21] Langerhans cell histiocytosis. Wikipedia (2015) https://en.wikipedia.org/wiki/Langerhans_cell_histiocytosis Accessed on February, 2 2016

[radio-22] Langerhans cell histiocytosis. Radiopeadia (2015) http://radiopaedia.org/articles/langerhans-cell-histiocytosis Accessed on February, 3 2016

[23] Epstein EH, Shepard JA, Flotte TJ (2008). "Case records of the Massachusetts General Hospital. Case 3-2008. An 80-year-old woman with cutaneous basal-cell carcinomas and cysts of the jaws". N Engl J Med. 358 (4): 393–401. doi:10.1056/NEJMcpc0707893. PMID 18216361. Unknown parameter |month= ignored (help)

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@@ Line 1: / Line 1: @@
 __NOTOC__
-{{Molluscum contagiosum}}
+[[Image:Home_logo1.png|right|250px|link=https://www.wikidoc.org/index.php/Molluscum_contagiosum]]
 {{CMG}}; {{AE}} {{MIR}}, {{JS}}
@@ Line 7: / Line 7: @@
 ==Differential Diagnosis==
-Molluscum contagiosum must be differentiated from other inflammatory, ulcerative skin, mucosal or genital lesions
+Different conditions that cause a round [[papular]] [[rash]] must be differentiated from [[molluscum contagiosum]] based on the appearance of the [[lesions]] such as:<ref name="pmid25250996">{{cite journal| author=Hartman-Adams H, Banvard C, Juckett G| title=Impetigo: diagnosis and treatment. | journal=Am Fam Physician | year= 2014 | volume= 90 | issue= 4 | pages= 229-35 | pmid=25250996 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25250996  }} </ref><ref name="pmid27265069">{{cite journal| author=Mehta N, Chen KK, Kroumpouzos G| title=Skin disease in pregnancy: The approach of the obstetric medicine physician. | journal=Clin Dermatol | year= 2016 | volume= 34 | issue= 3 | pages= 320-6 | pmid=27265069 | doi=10.1016/j.clindermatol.2016.02.003 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27265069  }} </ref><ref name="MooreSeward2006">{{cite journal|last1=Moore|first1=Zack S|last2=Seward|first2=Jane F|last3=Lane|first3=J Michael|title=Smallpox|journal=The Lancet|volume=367|issue=9508|year=2006|pages=425–435|issn=01406736|doi=10.1016/S0140-6736(06)68143-9}}</ref><ref name="pmid26612370">{{cite journal| author=Ibrahim F, Khan T, Pujalte GG| title=Bacterial Skin Infections. | journal=Prim Care | year= 2015 | volume= 42 | issue= 4 | pages= 485-99 | pmid=26612370 | doi=10.1016/j.pop.2015.08.001 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26612370  }} </ref><ref name="pmid26566601">{{cite journal| author=Ramoni S, Boneschi V, Cusini M| title=Syphilis as "the great imitator": a case of impetiginoid syphiloderm. | journal=Int J Dermatol | year= 2016 | volume= 55 | issue= 3 | pages= e162-3 | pmid=26566601 | doi=10.1111/ijd.13072 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26566601  }} </ref><ref name="pmid25855021">{{cite journal| author=Kimura U, Yokoyama K, Hiruma M, Kano R, Takamori K, Suga Y| title=Tinea faciei caused by Trichophyton mentagrophytes (molecular type Arthroderma benhamiae ) mimics impetigo : a case report and literature review of cases in Japan. | journal=Med Mycol J | year= 2015 | volume= 56 | issue= 1 | pages= E1-5 | pmid=25855021 | doi=10.3314/mmj.56.E1 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25855021  }} </ref><ref name="pmid23176858">{{cite journal| author=CEDEF| title=[Item 87--Mucocutaneous bacterial infections]. | journal=Ann Dermatol Venereol | year= 2012 | volume= 139 | issue= 11 Suppl | pages= A32-9 | pmid=23176858 | doi=10.1016/j.annder.2012.01.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23176858  }} </ref>
 {| class="wikitable sortable"
 ! style="width: 200px; background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Disease}}
@@ Line 13: / Line 13: @@
 ! style="width: 200px; background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Images}}
 |-
-| style="background: #DCDCDC; padding: 5px;" |[[Cryptococcosis]]
+| style="background: #DCDCDC; padding: 5px;" |Molluscum contagiosum
 |
-*An infection acquired by inhalation of soil contaminated with the encapsulated yeast (fungus) [[Cryptococcus neoformans]]
+*Skin [[papules]]:
-*May be completely asymptomatic, or may have latent infection or symptomatic disease.
+**Firm
-*[[Pneumonia]]-like illness with [[fever]], [[cough]], sputum production and chest pain.
+**Dome shaped
-*May cause [[meningoencephalitis]] presenting with [[headache]], [[nausea]], [[vomiting]], altered sensorium and focal neurological deficits.
+**Shiny
+**2 to 5 mm diameter
+**May have central indentation or [[umbilication]]
+*Polypoid lesion: Occasionally, with a stalk-like base
+*Visibly inflamed lesions occasionally may be seen
+*[[Erythema|Diffuse erythema]]: May be seen due to [[Gianotti-Crosti syndrome|Gianotti-Crosti]] like eruptions
+|
+[[File:Molluscumcontagiosum1.jpg|300px]]
+|-
+| style="background: #DCDCDC; padding: 5px;" |[[Cryptococcosis]]<ref name="pmid26936349">{{cite journal |vauthors=Miyazato A |title=[Mechanism of Cryptococcus Meningoencephalitis] |language=Japanese |journal=Med Mycol J |volume=57 |issue=1 |pages=J27–32 |year=2016 |pmid=26936349 |doi=10.3314/mmj.57.J27 |url=}}</ref>
+|
+*Caused by encapsulated yeast ([[fungus]]) [[Cryptococcus neoformans]]
+*May be completely asymptomatic
+*May have latent infection or symptomatic disease
+*[[Pneumonia]]-like illness with [[fever]], [[cough]], [[sputum]] production and [[chest pain]]
+*May lead to:
+**[[Meningoencephalitis]]
 |
 [[File:Cryptococcosis05.jpeg|300px]]
@@ Line 24: / Line 40: @@
 | style="background: #DCDCDC; padding: 5px;" |[[Histoplasmosis]]<br> <ref name="pmid20463244">{{cite journal| author=Knox KS, Hage CA| title=Histoplasmosis. | journal=Proc Am Thorac Soc | year= 2010 | volume= 7 | issue= 3 | pages= 169-72 | pmid=20463244 | doi=10.1513/pats.200907-069AL | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20463244  }} </ref><ref name="pmid19375629">{{cite journal| author=Kauffman CA| title=Histoplasmosis. | journal=Clin Chest Med | year= 2009 | volume= 30 | issue= 2 | pages= 217-25, v | pmid=19375629 | doi=10.1016/j.ccm.2009.02.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19375629  }} </ref><ref name="pmid18158437">{{cite journal |author=Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, Brun-Buisson C, Beale R, Calandra T, Dhainaut JF, Gerlach H, Harvey M, Marini JJ, Marshall J, Ranieri M, Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL |title=Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008 |journal=[[Critical Care Medicine]] |volume=36 |issue=1 |pages=296–327 |year=2008 |month=January |pmid=18158437 |doi=10.1097/01.CCM.0000298158.12101.41 |url=http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0090-3493&volume=36&issue=1&spage=296 |accessdate=2012-09-16}}</ref><ref>Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest. 1992 Jun;101(6):1644-55. PMID 1303622.</ref>
 |
-*Acquired via inhalation of airborne microconidia.
+*Acquired via inhalation of airborne microconidia
 *Can present with:
 **Acute pulmonary [[histoplasmosis]] presenting with [[fever]], [[cough]] and [[dyspnea]]
 **[[Skin rash]]
 **Symmetrical [[joint pain]]
-**Disseminated [[histoplasmosis]] presents with features of [[sepsis]], [[acute respiratory distress syndrome]] and [[disseminated intravascular coagulation]]
+**Disseminated [[histoplasmosis]] presents with:
+***[[Sepsis]]
+***[[Acute respiratory distress syndrome|Acute respiratory distress syndrome]]
+***[[Disseminated intravascular coagulation]]
 |
 [[File:Histoplasmosis07.jpeg|300px]]
@@ Line 35: / Line 54: @@
 | style="background: #DCDCDC; padding: 5px;" |[[Penicillium marneffei]]<ref name="pmid1339213">{{cite journal| author=Supparatpinyo K, Chiewchanvit S, Hirunsri P, Baosoung V, Uthammachai C, Chaimongkol B et al.| title=An efficacy study of itraconazole in the treatment of Penicillium marneffei infection. | journal=J Med Assoc Thai | year= 1992 | volume= 75 | issue= 12 | pages= 688-91 | pmid=1339213 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1339213  }} </ref>
 |
-*Considered rare, its occurrence has increased due to [[AIDS]].
+*[[Fever]]
-*[[Fever]], [[skin lesion]]s, [[anemia]], generalized [[lymphadenopathy]], and [[hepatomegaly]].
+*[[Skin lesion]]s
+*[[Anemia]]
+*Generalized [[lymphadenopathy]]
+*[[Hepatomegaly]]
 |
@@ Line 42: / Line 64: @@
 | style="background: #DCDCDC; padding: 5px;" |[[Condyloma acuminatum]] <ref name="Bloomberg">[http://www.bloomberg.com/apps/news?pid=20601202&sid=aajzweDaXZh0&refer=healthcare Cortez, Michelle Fay and Pettypiece, Shannon. "Merck Cancer Shot Cuts Genital Warts, Lesions in Men". ''Bloomberg News''. (Bloomberg.com) 13 Nov 2008.]</ref>
 |
-*Spread through direct skin-to-skin contact during oral, genital, or anal sex with an infected partner.
+*Occur in [[Cluster (epidemiology)|clusters]]
-*Often occur in [[Cluster (epidemiology)|clusters]] and can be very tiny or can spread into large masses in the genital or penis area.
+*May be very tiny
+*May spread into large masses in the [[genital]] or [[penis]] area
 |
 [[File:Condyloma acuminatum07.jpg|300px]]
 |-
-| style="background: #DCDCDC; padding: 5px;" |[[Pyogenic granuloma]]
+| style="background: #DCDCDC; padding: 5px;" |[[Pyogenic granuloma]]<ref name="Fitz2">Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.</ref><ref name="joralsci">{{cite journal | author = Jafarzadeh H, Sanatkhani M, Mohtasham N | title = Oral pyogenic granuloma: a review | journal = J Oral Sci | volume = 48 | issue = 4 | pages = 167–75 |date=December 2006 | pmid = 17220613 | doi = 10.2334/josnusd.48.167| url = http://joi.jlc.jst.go.jp/JST.JSTAGE/josnusd/48.167?from=PubMed| accessdate = 2009-01-04 | format =  &ndash; <sup>[http://scholar.google.co.uk/scholar?hl=en&lr=&q=intitle%3AOral+pyogenic+granuloma%3A+a+review&as_publication=J+Oral+Sci&as_ylo=2006&as_yhi=2006&btnG=Search Scholar search]</sup>}} {{dead link|date=March 2009}}</ref><ref name="Nthumba">{{cite journal |author=Nthumba PM |title=Giant pyogenic granuloma of the thigh: a case report |journal=J Med Case Reports |volume=2 |issue= 1|pages=95 |year=2008 |pmid=18377654 |pmc=2329656 |doi=10.1186/1752-1947-2-95 |url=http://www.jmedicalcasereports.com/content/2//95}}</ref>
 |
-* A vascular lesion that occurs on both mucosa and skin, and appears as an [[hyperplasia|overgrowth]] of tissue due to [[irritation]], [[physical trauma]] or [[hormones|hormonal]] factors.<ref name="Fitz2">Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.</ref><ref name="joralsci">{{cite journal | author = Jafarzadeh H, Sanatkhani M, Mohtasham N | title = Oral pyogenic granuloma: a review | journal = J Oral Sci | volume = 48 | issue = 4 | pages = 167–75 |date=December 2006 | pmid = 17220613 | doi = 10.2334/josnusd.48.167| url = http://joi.jlc.jst.go.jp/JST.JSTAGE/josnusd/48.167?from=PubMed| accessdate = 2009-01-04 | format =  &ndash; <sup>[http://scholar.google.co.uk/scholar?hl=en&lr=&q=intitle%3AOral+pyogenic+granuloma%3A+a+review&as_publication=J+Oral+Sci&as_ylo=2006&as_yhi=2006&btnG=Search Scholar search]</sup>}} {{dead link|date=March 2009}}</ref>
+*A vascular lesion occurs on both [[Mucosal|mucosa]] and skin
-*Involve the gums, the skin and [[nasal septum]], and has also been found far from the head such as in the thigh.<ref name="Nthumba">{{cite journal |author=Nthumba PM |title=Giant pyogenic granuloma of the thigh: a case report |journal=J Med Case Reports |volume=2 |issue= 1|pages=95 |year=2008 |pmid=18377654 |pmc=2329656 |doi=10.1186/1752-1947-2-95 |url=http://www.jmedicalcasereports.com/content/2//95}}</ref>
+*Appears as an [[hyperplasia|overgrowth]] of tissue due to [[irritation]], [[physical trauma]] or [[hormones|hormonal]] factors
+*Involve the gums, the skin and [[nasal septum]], and has also been found far from the head such as in the thigh
 |
 [[File:Granuloma pyogenic 16.jpeg|300px]]
 |-
-| style="background: #DCDCDC; padding: 5px;" |[[Langerhans cell histiocytosis]]
+| style="background: #DCDCDC; padding: 5px;" |[[Langerhans cell histiocytosis]]<ref name="pmid25310214">{{cite journal| author=Grana N| title=Langerhans cell histiocytosis. | journal=Cancer Control | year= 2014 | volume= 21 | issue= 4 | pages= 328-34 | pmid=25310214 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25310214  }} </ref><ref name="pmid26414464">{{cite journal| author=Harmon CM, Brown N| title=Langerhans Cell Histiocytosis: A Clinicopathologic Review and Molecular Pathogenetic Update. | journal=Arch Pathol Lab Med | year= 2015 | volume= 139 | issue= 10 | pages= 1211-4 | pmid=26414464 | doi=10.5858/arpa.2015-0199-RA | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26414464  }} </ref><ref name="pmid25281259">{{cite journal| author=DiCaprio MR, Roberts TT| title=Diagnosis and Management of Langerhans Cell Histiocytosis. | journal=J Am Acad Orthop Surg | year= 2014 | volume= 22 | issue= 10 | pages= 643-652 | pmid=25281259 | doi=10.5435/JAAOS-22-10-643 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25281259  }} </ref><ref name="wiki">Langerhans cell histiocytosis. Wikipedia (2015) https://en.wikipedia.org/wiki/Langerhans_cell_histiocytosis Accessed on February, 2 2016</ref><ref name="radio">Langerhans cell histiocytosis. Radiopeadia (2015) http://radiopaedia.org/articles/langerhans-cell-histiocytosis Accessed on February, 3 2016</ref>
 |
-*Result of either a true [[neoplastic]] process or a reactive [[immune]] condition.<ref name="pmid25281259">{{cite journal| author=DiCaprio MR, Roberts TT| title=Diagnosis and Management of Langerhans Cell Histiocytosis. | journal=J Am Acad Orthop Surg | year= 2014 | volume= 22 | issue= 10 | pages= 643-652 | pmid=25281259 | doi=10.5435/JAAOS-22-10-643 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25281259  }} </ref><ref name="pmid25310214">{{cite journal| author=Grana N| title=Langerhans cell histiocytosis. | journal=Cancer Control | year= 2014 | volume= 21 | issue= 4 | pages= 328-34 | pmid=25310214 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25310214  }} </ref><ref name="pmid26414464">{{cite journal| author=Harmon CM, Brown N| title=Langerhans Cell Histiocytosis: A Clinicopathologic Review and Molecular Pathogenetic Update. | journal=Arch Pathol Lab Med | year= 2015 | volume= 139 | issue= 10 | pages= 1211-4 | pmid=26414464 | doi=10.5858/arpa.2015-0199-RA | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26414464  }} </ref>
+*Result of either a true [[neoplastic]] process or a reactive [[immune]] condition.
-*Common symptoms of Langerhans cell histiocytosis include [[bone]] pain, [[rash]], [[fever]], and [[failure to thrive]].<ref name="wiki">Langerhans cell histiocytosis. Wikipedia (2015) https://en.wikipedia.org/wiki/Langerhans_cell_histiocytosis Accessed on February, 2 2016</ref><ref name="radio">Langerhans cell histiocytosis. Radiopeadia (2015) http://radiopaedia.org/articles/langerhans-cell-histiocytosis Accessed on February, 3 2016</ref><ref name="PDQ">Langerhans Cell Histiocytosis Treatment (PDQ®): Health Professional Version.  National Cancer Institute (2015) http://www.cancer.gov/types/langerhans/hp/langerhans-treatment-pdq Accessed on February, 3 2016</ref>
+*Common symptoms of Langerhans cell histiocytosis include:
-*scaly erythematous lesions located on the scalp and extremities, localized [[bone]] [[tenderness]], and [[hepatosplenomegaly]].<ref name="PDQ">Langerhans Cell Histiocytosis Treatment (PDQ®): Health Professional Version.  National Cancer Institute (2015) http://www.cancer.gov/types/langerhans/hp/langerhans-treatment-pdq Accessed on February, 3 2016</ref><ref name="wiki">Langerhans cell histiocytosis. Wikipedia (2015) https://en.wikipedia.org/wiki/Langerhans_cell_histiocytosis Accessed on February, 2 2016</ref>
+**[[Bone]] pain
+**[[Rash]]
+**[[Fever]]
+**[[Failure to thrive]]
+*Scaly [[Erythema|erythematous lesions]] located on the scalp and extremities
+*Localized [[bone]] [[tenderness]]
+*[[Hepatosplenomegaly]]
 |
 [[File:Langerhans cell histiocytosis08.jpg|300px]]
@@ Line 65: / Line 95: @@
 |
-* Develop in the basal cell layer of the skin.
-* Cumulative DNA damage leads to mutations, after sunlight exposure.
 * Skin growths on sun-exposed skin
+* [[Ulcerated lesion|Ulcerative pupils]]
 |
 [[File:Basal cell carcinoma 01.jpeg|300px]]
@@ Line 73: / Line 102: @@
 | style="background: #DCDCDC; padding: 5px;" |[[Amelanotic melanoma]]
 |
-* [[Amelanotic melanoma|Amelanotic]] or hypomelanotic lesions or maybe [[nodular]] and desmoplastic subtypes
+* [[Amelanotic melanoma|Amelanotic]] or [[Hypomelanosis|hypomelanotic lesions]] or maybe [[nodular]] and desmoplastic subtypes
-* Lesions may present as pink or red [[Macule|macules]], plaques, or nodules, often with well-defined borders
+* Lesions may present as pink or red [[Macule|macules]], [[Plaque|plaques]], or [[nodules]], often with well-defined borders
 * Often clinically confused with benign lesions
 |
 [[File:Melanoma 08.jpg|300px]]
-|}
-Different conditions that cause a [[rash]] must be differentiated from [[molluscum contagiosum]] based on the appearance of the lesions such as:<ref name="pmid25250996">{{cite journal| author=Hartman-Adams H, Banvard C, Juckett G| title=Impetigo: diagnosis and treatment. | journal=Am Fam Physician | year= 2014 | volume= 90 | issue= 4 | pages= 229-35 | pmid=25250996 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25250996  }} </ref><ref name="pmid27265069">{{cite journal| author=Mehta N, Chen KK, Kroumpouzos G| title=Skin disease in pregnancy: The approach of the obstetric medicine physician. | journal=Clin Dermatol | year= 2016 | volume= 34 | issue= 3 | pages= 320-6 | pmid=27265069 | doi=10.1016/j.clindermatol.2016.02.003 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27265069  }} </ref><ref name="MooreSeward2006">{{cite journal|last1=Moore|first1=Zack S|last2=Seward|first2=Jane F|last3=Lane|first3=J Michael|title=Smallpox|journal=The Lancet|volume=367|issue=9508|year=2006|pages=425–435|issn=01406736|doi=10.1016/S0140-6736(06)68143-9}}</ref><ref name="pmid26612370">{{cite journal| author=Ibrahim F, Khan T, Pujalte GG| title=Bacterial Skin Infections. | journal=Prim Care | year= 2015 | volume= 42 | issue= 4 | pages= 485-99 | pmid=26612370 | doi=10.1016/j.pop.2015.08.001 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26612370  }} </ref><ref name="pmid26566601">{{cite journal| author=Ramoni S, Boneschi V, Cusini M| title=Syphilis as "the great imitator": a case of impetiginoid syphiloderm. | journal=Int J Dermatol | year= 2016 | volume= 55 | issue= 3 | pages= e162-3 | pmid=26566601 | doi=10.1111/ijd.13072 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26566601  }} </ref><ref name="pmid25855021">{{cite journal| author=Kimura U, Yokoyama K, Hiruma M, Kano R, Takamori K, Suga Y| title=Tinea faciei caused by Trichophyton mentagrophytes (molecular type Arthroderma benhamiae ) mimics impetigo : a case report and literature review of cases in Japan. | journal=Med Mycol J | year= 2015 | volume= 56 | issue= 1 | pages= E1-5 | pmid=25855021 | doi=10.3314/mmj.56.E1 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25855021  }} </ref><ref name="pmid23176858">{{cite journal| author=CEDEF| title=[Item 87--Mucocutaneous bacterial infections]. | journal=Ann Dermatol Venereol | year= 2012 | volume= 139 | issue= 11 Suppl | pages= A32-9 | pmid=23176858 | doi=10.1016/j.annder.2012.01.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23176858  }} </ref>
-{| class="wikitable"
-! style="width: 200px; background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Disease}}
-! style="width: 200px; background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Features}}
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Impetigo]]
-|
-*It commonly presents with pimple-like lesions surrounded by [[erythematous]] [[skin]]. Lesions are [[pustules]], filled with [[pus]], which then break down over 4-6 days and form a thick crust. It's often associated with insect bites, cuts, and other forms of [[trauma]] to the [[skin]].
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Insect bite]]s
-|
-* The insect injects [[formic acid]], which can cause an immediate [[skin]] reaction often resulting in a [[rash]] and swelling in the injured area, often with formation of [[vesicles]].
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Kawasaki disease]]
-|
-* Commonly presents with high and persistent [[fever]], red [[mucous membranes]] in mouth, "[[strawberry tongue]]", [[swollen lymph nodes]] and [[skin rash]] in early disease, with peeling off of the [[skin]] of the [[hands]], [[feet]] and [[genital area]].
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Measles]]
-|
-* Commonly presents with high [[fever]], [[coryza]] and [[conjunctivitis]], with observation of [[oral mucosa|oral mucosal]] lesions ([[Koplik's spots]]), followed by widespread [[skin rash]].
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Monkeypox]]
-|
-* The presentation is similar to [[smallpox]], although it is often a milder form, with [[fever]], [[headache]], [[myalgia]], [[back pain]], [[swollen lymph nodes]], a general feeling of discomfort, and exhaustion. Within 1 to 3 days (sometimes longer) after the appearance of [[fever]], the patient develops a papular [[rash]], often first on the face. The lesions usually develop through several stages before crusting and falling off.
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Rubella]]
-|
-* Commonly presents with a facial [[rash]] which then spreads to the [[trunk]] and [[limbs]], fading after 3 days, low grade [[fever]], swollen [[glands]], [[joint pain]]s, [[headache]] and [[conjunctivitis]]. The [[rash]] disappears after a few days with no staining or peeling of the [[skin]]. ''[[Forchheimer's sign]]'' occurs in 20% of cases, and is characterized by small, red [[papules]] on the area of the [[soft palate]].
-|-
-| style="background: #DCDCDC; padding: 5px;" |Atypical [[measles]]
-|
-* The symptoms commonly begin about 7-14 days after infection and present as [[fever]], [[cough]], [[coryza]] and [[conjunctivitis]]. Observation of [[Koplik's spots]] is also a characteristic finding in measles.
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Coxsackievirus]]
-|
-* The most commonly caused disease is the [[Coxsackie A]] disease, presenting as ''hand, foot and mouth disease''. It may be [[asymptomatic]] or cause mild [[symptoms]], or it may produce [[fever]] and painful [[blisters]] in the mouth ([[herpangina]]), on the palms and fingers of the hand, or on the soles of the feet. There can also be [[blisters]] in the [[throat]]  or above the [[tonsils]]. Adults can also be affected. The [[rash]], which can appear several days after high temperature and painful sore throat, can be itchy and painful, especially on the hands/fingers and bottom of feet.
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Acne]]
-|
-* It is typical of teenagers, usually appears on the [[face]] and upper neck, but the [[chest]], [[human back|back]] and [[shoulder]]s may have [[acne]] as well. The upper [[arm]]s can also have [[acne]], but lesions found there are often [[keratosis pilaris]], not [[acne]]. The typical [[acne]] lesions are [[comedones]] and [[inflammatory]] [[papules]], [[pustules]], and [[nodules]]. Some of the large [[nodules]] were previously called "[[cyst]]s"
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Syphilis]]
-|It commonly presents with gneralized systemic [[symptoms]] such as [[malaise]], [[fatigue]], [[headache]] and [[fever]]. [[Skin]] eruptions may be subtle and [[asymptomatic]] It is classically described as:
-* Non-pruritic bilateral symmetrical mucocutaneous [[rash]]
-* Non-tender regional [[lymphadenopathy]]
-* Condylomata lata and
-* Patchy [[alopecia]].
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Molluscum contagiosum]]
-|
-* The lesions are commonly flesh-colored, dome-shaped, and pearly in appearance. They are often 1-5 millimeters in diameter, with a dimpled center. Generally not painful, but they may itch or become irritated. Picking or scratching the lesions may lead to further [[infection]] or scarring. In about 10% of the cases, [[eczema]] develops around the lesions. They may occasionally be complicated by secondary [[bacterial infections]].
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Mononucleosis]]
-|
-* Common [[symptoms]] include low-grade [[fever]] without [[chills]], [[sore throat]], white patches on [[tonsils]] and back of the throat, [[muscle weakness]] and sometime extreme [[fatigue]], tender [[lymphadenopathy]], [[petechial hemorrhage]] and [[skin rash]].
-|-
-| style="background: #DCDCDC; padding: 5px;" |Toxic [[erythema]]
-|
-* It is a common [[rash]] in infants, with clustered and [[vesicular]] appearance.
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Rat-bite fever]]
-|
-* It commonly presents with [[fever]], [[chills]], open sore at the site of the bite and [[rash]], which may show red or purple plaques.
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Parvovirus B19]]
-|
-*The [[rash]] of fifth disease is typically described as "slapped cheeks," with [[erythema]] across the cheeks and sparing the nasolabial folds, forehead, and mouth.
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Cytomegalovirus]]
-|
-* The common [[symptoms]] include [[sore throat]], swollen [[lymph nodes]], [[fever]], [[headache]], [[fatigue]], [[weakness]], [[muscle pain]]  and [[loss of appetite]].
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Scarlet fever]]
-|
-* It commonly includes [[fever]], punctate red [[macules]] on the hard and soft [[palate]] and [[uvula]] ([[Forchheimer's spots]]), bright red [[tongue]] with a "strawberry" appearance, [[sore throat]] and [[headache]] and [[lymphadenopathy]].
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Rocky Mountain spotted fever]]
-|
-* The [[symptoms]] may include [[maculopapular rash]], [[petechial rash]], [[abdominal pain]] and [[joint pain]].
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Stevens-Johnson syndrome]]
-|
-* The [[symptoms]] may include [[fever]], [[sore throat]]  and [[fatigue]]. Commonly presents [[ulcers]] and other lesions in the [[mucous membranes]], almost always in the [[mouth]] and lips but also in the genital and anal regions. Those in the mouth are usually extremely painful and reduce the patient's ability to eat or drink. [[Conjunctivitis]] of the eyes occurs in about 30% of children. A [[rash]] of round lesions about an inch across, may arise on the face, trunk, arms and legs, and soles of the feet, but usually not on the scalp.
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Varicella-zoster virus]]
-|
-* It commonly starts as a painful [[rash]] on one side of the face or body. The [[rash]] forms blisters that typically scab over in 7-10 days and clears up within 2-4 weeks.
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Chickenpox]]
-|
-* It commonly starts with [[conjunctival]] and catarrhal [[symptoms]] and then characteristic spots appearing in two or three waves, mainly on the body and head, rather than the hands, becoming itchy raw pox (small open sores which heal mostly without scarring). Touching the fluid from a [[chickenpox]] blister can also spread the disease.
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Meningococcemia]]
-|
-* It commonly presents with [[rash]], [[petechiae]], [[headache]], [[confusion]], and [[stiff neck]], high [[fever]], mental status changes, [[nausea]] and [[vomiting]].
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Rickettsialpox|Rickettsial pox]]
-|
-* The first [[symptom]] is commonly a bump formed by a mite-bite, eventually resulting in a black, crusty scab. Many of the [[symptoms]] are [[flu]]-like including [[fever]], [[chills]], [[weakness]] and [[muscle pain]] but the most distinctive [[symptom]] is the [[rash]] that breaks out, spanning the person's entire body.
-|-
-| style="background: #DCDCDC; padding: 5px;" |[[Meningitis]]
-|
-* It commonly presents with [[headache]], [[nuchal rigidity]], [[fever]], [[petechiae]] and [[altered mental status]].
 |}
 ==References==
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Molluscum contagiosum differential diagnosis: Difference between revisions

Latest revision as of 22:45, 29 July 2020

Overview

Differential Diagnosis

References

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