Intraprocedural thrombotic events
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: IPTE
Overview
Intraprocedural thrombotic events (IPTE) are a rare group of acute ischemic complications that occur during percutaneous coronary interventions (PCI). Although by definition IPTE should occur before the end of the PCI procedure; it can however come about before or after stent-placement during PCI. In contrast to other complications that might occur before or after PCI, IPTE has recently been recognized as a special category of complications that include distinctive risk factors, associated patient and procedural characteristics, and most importantly comprises a unique predictor of periprocedural and postprocedural adverse clinical outcomes and overall patient prognosis. As such, the emergent objective understanding of IPTE and its reproducible effects is expected to render IPTE as a clinical end-point in PCI rather than a mere intraprocedural observation.[1][2]
Classification
- New thrombus formation
- Increased thrombus size
- Abrupt vessel closure
- No reflow phenomenon (new TIMI flow grade 0 or 1)
- Slow reflow phenomenon (new TIMI flow grade 2)
- Distal embolization
- Loss of side branch
- Intraprocedural stent thrombosis (IPST)
Epidemiology and Demographics
References
- ↑ Pride YB, Mohanavelu S, Zorkun C, Kunadian V, Giugliano RP, Newby LK; et al. (2012). "Association between angiographic complications and clinical outcomes among patients with acute coronary syndrome undergoing percutaneous coronary intervention: an EARLY ACS (Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome) angiographic substudy". JACC Cardiovasc Interv. 5 (9): 927–35. doi:10.1016/j.jcin.2012.05.007. PMID 22995880.
- ↑ McEntegart MB, Kirtane AJ, Cristea E, Brener S, Mehran R, Fahy M; et al. (2012). "Intraprocedural thrombotic events during percutaneous coronary intervention in patients with non-ST-segment elevation acute coronary syndromes are associated with adverse outcomes: analysis from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial". J Am Coll Cardiol. 59 (20): 1745–51. doi:10.1016/j.jacc.2012.02.019. PMID 22575311.