Hemolytic-uremic syndrome causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Causes

• Childhood HUS

• After enterohemorrhagic E. Coli (usually O157:H7)
• Idiopathic

• Adult TTP-HUS

• Idiopathic
• Drug toxicity

• Mitomycin C, cyclosporine, Desogestrel and Ethinyl Estradiol, Gemcitabine, Sulfasalazine

• Immune mediated:

• Quinine
• Ticlopidine
• Clopidogrel
• Bleomycin
• Cisplatin
• OCPs
• Tacrolimus
• Valacyclovir
• Rifampin

Simvastatin

• Penicillin
• Quinolones
• Risperidone

• MDS
• Conditioning for BMT
• Pregnancy or postpartum
• Autoimmune disease (APL syndrome, SLE, scleroderma)
• HIV/AIDS
• CMV
• Tuberculosis
• After enterohemorrhagic E. Coli