Granulocytosis: Difference between revisions

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Revision as of 20:04, 5 December 2012

WikiDoc Resources for Granulocytosis

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Articles on Granulocytosis in N Eng J Med, Lancet, BMJ

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Definitions

Definitions of Granulocytosis

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Causes & Risk Factors for Granulocytosis

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List of terms related to Granulocytosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Lakshmi Gopalakrishnan, M.B.B.S. [2]

Overview

Granulocytosis is defined as the presence of an increased number of granulocytes, a category of white blood cells present in the peripheral blood. Often, the word refers to an increased neutrophil granulocyte count, as neutrophils are the main granulocytes. An increase in eosinophil granulocyte is known as eosinophilia. In cardiovascular disease, increased white blood cell counts have been shown to indicate a worse prognosis.

Common Causes

Granulocytosis can be a feature of a number of diseases:

Causes by Organ System

Cardiovascular No underlying causes
Chemical / poisoning No underlying causes
Dermatologic No underlying causes
Drug Side Effect Aminophylline, Dinoprostone, Filgrastim, Granulocyte colony stimulating factor, Granulocyte-macrophage colony stimulating factor, Lithium, Sulprostone
Ear Nose Throat No underlying causes
Endocrine No underlying causes
Environmental No underlying causes
Gastroenterologic Acute pancreatitis, Gallbladder empyema
Genetic Acute intermittent porphyria, Hereditary neutrophilia, Hyperimmunoglobulinemia D and periodic fever syndrome, Leukocyte adhesion deficiency type 1, Leukocyte adhesion deficiency type 2, Leukocyte adhesion deficiency type 3, Recurrent hereditary polyserositis
Hematologic Acute intermittent porphyria, Leukemoid reaction, Leukocyte adhesion deficiency type 1, Leukocyte adhesion deficiency type 2, Leukocyte adhesion deficiency type 3, Lymphangitis, Polycythaemia rubra vera, Recurrent hereditary polyserositis
Iatrogenic Splenectomy
Infectious Disease Congenital syphilis, Hantavirus
Musculoskeletal / Ortho No underlying causes
Neurologic No underlying causes
Nutritional / Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic Acute myeloid leukemia, Acute promyelocytic leukemia, Chronic myeloid leukaemia, Mast cell leukemia, Polycythaemia rubra vera
Opthalmologic No underlying causes
Overdose / Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary Bronchiolitis obliterans organizing pneumonia, Extrinsic allergic alveolitis, Wegener granulomatosis, Severe acute respiratory syndrome
Renal / Electrolyte Wegener granulomatosis
Rheum / Immune / Allergy Adult-onset Still disease, Urate crystal arthropathy, Wegener granulomatosis
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous No underlying causes

Causes in Alphabetical Order

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