Familial mediterranean fever natural history, complications and prognosis: Difference between revisions
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[[amyloidosis|AA-amyloidosis]] with [[renal failure]] is a complication and may develop without overt crises. AA (amyloid protein) is produced in very large quantities during attacks and at a low rate between them, and accumulates mainly in the [[kidney]], as well as the [[heart]], [[spleen]], [[gastrointestinal tract]] and the [[thyroid]].<ref name=Livneh/> | [[amyloidosis|AA-amyloidosis]] with [[renal failure]] is a complication and may develop without overt crises. AA (amyloid protein) is produced in very large quantities during attacks and at a low rate between them, and accumulates mainly in the [[kidney]], as well as the [[heart]], [[spleen]], [[gastrointestinal tract]] and the [[thyroid]].<ref name=Livneh/> | ||
There appears to be an increase in the risk for developing particular [[vasculitis]] | There appears to be an increase in the risk for developing particular [[vasculitis]] related diseases (e.g. [[Henoch-Schönlein purpura]]), [[spondylarthropathy]], prolonged [[arthritis]] of certain joints and protracted [[myalgia]].<ref name=Livneh>Livneh A, Langevitz P. Diagnostic and treatment concerns in familial Mediterranean fever. ''Baillieres Best Pract Res Clin Rheumatol'' 2000;14(3):477-98. PMID 10985982.</ref> | ||
==Prognosis== | ==Prognosis== | ||
There is no known cure for familial mediterranean fever. Most people continue to have attacks, but the number and severity of attacks is different from person to person. | There is no known cure for familial mediterranean fever. Most people continue to have attacks, but the number and severity of attacks is different from person to person. | ||
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{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Needs content]] | [[Category:Needs content]] | ||
[[Category:Arthritis]] | |||
[[Category:Rheumatology]] | |||
[[Category:Gastroenterology]] | |||
[[Category:Immune system disorders]] | |||
[[Category:Genetic disorders]] | |||
[[Category:Inborn errors of metabolism]] | |||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Needs overview]] | [[Category:Needs overview]] |
Revision as of 21:29, 5 March 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Complications
AA-amyloidosis with renal failure is a complication and may develop without overt crises. AA (amyloid protein) is produced in very large quantities during attacks and at a low rate between them, and accumulates mainly in the kidney, as well as the heart, spleen, gastrointestinal tract and the thyroid.[1]
There appears to be an increase in the risk for developing particular vasculitis related diseases (e.g. Henoch-Schönlein purpura), spondylarthropathy, prolonged arthritis of certain joints and protracted myalgia.[1]
Prognosis
There is no known cure for familial mediterranean fever. Most people continue to have attacks, but the number and severity of attacks is different from person to person.