Familial mediterranean fever natural history, complications and prognosis: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{Familial mediterranean fever}} | {{Familial mediterranean fever}} | ||
{{CMG}} | {{CMG}}; {{AE}} {{Sahar}} | ||
==Overview== | |||
Common complications of familial Mediterranean fever include amyloidosis and increased risk of vasculitis associated disorder | |||
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%. | |||
==Natural History, Complications, and Prognosis== | |||
===Natural History=== | |||
*The symptoms of familial Mediterranean fever usually develop in the first two decades of life and start with symptoms such as fever and serositis. | |||
Serositis may include, but not limited to: | |||
*If left untreated, [#]% of patients with [disease name] may progress to develop amyloidosis, [manifestation 2], and [manifestation 3]. | |||
==Complications== | ==Complications== | ||
[[amyloidosis|AA-amyloidosis]] with [[renal failure]] is a complication and may develop without overt crises. AA (amyloid protein) is produced in very large quantities during attacks and at a low rate between them, and accumulates mainly in the [[kidney]], as well as the [[heart]], [[spleen]], [[gastrointestinal tract]] and the [[thyroid]].<ref name=Livneh/> | [[amyloidosis|AA-amyloidosis]] with [[renal failure]] is a complication and may develop without overt crises. AA (amyloid protein) is produced in very large quantities during attacks and at a low rate between them, and accumulates mainly in the [[kidney]], as well as the [[heart]], [[spleen]], [[gastrointestinal tract]] and the [[thyroid]].<ref name=Livneh/> | ||
Line 10: | Line 16: | ||
There appears to be an increase in the risk for developing particular [[vasculitis]] related diseases (e.g. [[Henoch-Schönlein purpura]]), [[spondylarthropathy]], prolonged [[arthritis]] of certain joints and protracted [[myalgia]].<ref name=Livneh>Livneh A, Langevitz P. Diagnostic and treatment concerns in familial Mediterranean fever. ''Baillieres Best Pract Res Clin Rheumatol'' 2000;14(3):477-98. PMID 10985982.</ref> | There appears to be an increase in the risk for developing particular [[vasculitis]] related diseases (e.g. [[Henoch-Schönlein purpura]]), [[spondylarthropathy]], prolonged [[arthritis]] of certain joints and protracted [[myalgia]].<ref name=Livneh>Livneh A, Langevitz P. Diagnostic and treatment concerns in familial Mediterranean fever. ''Baillieres Best Pract Res Clin Rheumatol'' 2000;14(3):477-98. PMID 10985982.</ref> | ||
==Prognosis== | ==Prognosis== | ||
There is no known cure for familial | There is no known cure for familial Mediterranean fever. Most people continue to have attacks, but the number and severity of attacks is different from person to person. | ||
*Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [--]%. | |||
*The presence of amyloidosis is associated with a particularly [good/poor] prognosis among patients with familial Mediterranean fever. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Needs content]] | [[Category:Needs content]] | ||
[[Category:Arthritis]] | [[Category:Arthritis]] |
Revision as of 19:21, 21 May 2019
Familial Mediterranean Fever Microchapters |
Differentiating Familial Mediterranean Fever from other Diseases |
---|
Diagnosis |
Treatment |
Case Studies |
Familial mediterranean fever natural history, complications and prognosis On the Web |
American Roentgen Ray Society Images of Familial mediterranean fever natural history, complications and prognosis |
FDA on Familial mediterranean fever natural history, complications and prognosis |
CDC on Familial mediterranean fever natural history, complications and prognosis |
Familial mediterranean fever natural history, complications and prognosis in the news |
Blogs on Familial mediterranean fever natural history, complications and prognosis |
Directions to Hospitals Treating Familial mediterranean fever |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
Common complications of familial Mediterranean fever include amyloidosis and increased risk of vasculitis associated disorder Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of familial Mediterranean fever usually develop in the first two decades of life and start with symptoms such as fever and serositis.
Serositis may include, but not limited to:
- If left untreated, [#]% of patients with [disease name] may progress to develop amyloidosis, [manifestation 2], and [manifestation 3].
Complications
AA-amyloidosis with renal failure is a complication and may develop without overt crises. AA (amyloid protein) is produced in very large quantities during attacks and at a low rate between them, and accumulates mainly in the kidney, as well as the heart, spleen, gastrointestinal tract and the thyroid.[1]
There appears to be an increase in the risk for developing particular vasculitis related diseases (e.g. Henoch-Schönlein purpura), spondylarthropathy, prolonged arthritis of certain joints and protracted myalgia.[1]
Prognosis
There is no known cure for familial Mediterranean fever. Most people continue to have attacks, but the number and severity of attacks is different from person to person.
- Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [--]%.
- The presence of amyloidosis is associated with a particularly [good/poor] prognosis among patients with familial Mediterranean fever.