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| __NOTOC__ | | __NOTOC__ |
| {{Familial adenomatous polyposis}}
| | [[Image:Home_logo1.png|right|250px|link=https://www.wikidoc.org/index.php/Familial_adenomatous_polyposis]] |
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| {{CMG}} {{AE}} {{MJK}} | | {{CMG}} {{AE}} {{SSH}}, {{MJK}} |
| ==Overview== | | ==Overview== |
| Familial adenomatous polyposis must be differentiated from other diseases that cause multiple [[Polyp|polyps]], such as [[Peutz-Jeghers syndrome]], familial juvenile polyps or hyperplastic polyposis, hereditary mixed polyposis syndromes, and [[Hereditary nonpolyposis colorectal cancer|Lynch syndrome]]. | | Familial adenomatous polyposis must be differentiated from other diseases that cause multiple [[Polyp|polyps]], such as [[Peutz-Jeghers syndrome|Peutz–Jeghers syndrome]], [[juvenile polyposis syndrome]], [[Cowden syndrome]], [[Carney syndrome]], and [[Hereditary nonpolyposis colorectal cancer|hereditary non–polyposis colon cancer]] ([[Hereditary nonpolyposis colorectal cancer|Lynch syndrome]]). |
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| ==Differentiating familial adenomatous polyposis from other Diseases== | | ==Differentiating familial adenomatous polyposis from other Diseases== |
| * Familial adenomatous polyposis must be differentiated from other diseases that cause multiple [[Polyp|polyps]] including:
| | Familial adenomatous polyposis must be differentiated from other diseases that cause multiple [[Polyp|polyps]] including:<ref name="pmid20301519">{{cite journal |vauthors=Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, Jasperson KW, Patel SG, Ahnen DJ |title=APC-Associated Polyposis Conditions. |journal= |volume= |issue= |pages= |year= |pmid=20301519 |doi= |url=}}</ref><ref name="pmid11446392">{{cite journal |vauthors=Beech D, Pontius A, Muni N, Long WP |title=Familial adenomatous polyposis: a case report and review of the literature |journal=J Natl Med Assoc |volume=93 |issue=6 |pages=208–13 |year=2001 |pmid=11446392 |pmc=2594024 |doi= |url=}}</ref><ref name="HalfBercovich2009">{{cite journal|last1=Half|first1=Elizabeth|last2=Bercovich|first2=Dani|last3=Rozen|first3=Paul|title=Familial adenomatous polyposis|journal=Orphanet Journal of Rare Diseases|volume=4|issue=1|year=2009|pages=22|issn=1750-1172|doi=10.1186/1750-1172-4-22}}</ref><ref name="NieuwenhuisVasen2007">{{cite journal|last1=Nieuwenhuis|first1=M.H.|last2=Vasen|first2=H.F.A.|title=Correlations between mutation site in APC and phenotype of familial adenomatous polyposis (FAP): A review of the literature|journal=Critical Reviews in Oncology/Hematology|volume=61|issue=2|year=2007|pages=153–161|issn=10408428|doi=10.1016/j.critrevonc.2006.07.004}}</ref><ref name="KingDozois2000">{{cite journal|last1=King|first1=John E.|last2=Dozois|first2=Roger R.|last3=Lindor|first3=Noralane M.|last4=Ahlquist|first4=David A.|title=Care of Patients and Their Families With Familial Adenomatous Polyposis|journal=Mayo Clinic Proceedings|volume=75|issue=1|year=2000|pages=57–67|issn=00256196|doi=10.4065/75.1.57}}</ref> |
| ** [[Peutz-Jeghers syndrome]]
| | * [[Peutz-Jeghers syndrome|Peutz–Jeghers syndrome]] |
| ** Familial juvenile polyps or hyperplastic polyposis | | * [[Juvenile polyposis syndrome]] |
| ** Hereditary mixed polyposis syndromes | | * [[Cowden syndrome]] |
| ** [[Hereditary nonpolyposis colorectal cancer|Lynch syndrome<br> ]] | | * [[Carney syndrome]] |
| | | * [[Lynch syndrome|Hereditary Non–Polyposis Colon Cancer]] ([[Hereditary nonpolyposis colorectal cancer|Lynch syndrome]]) |
| Differential diagnosis according to polys:
| |
| | |
| {| | | {| |
| |- style="background: #4479BA; color: #FFFFFF; text-align: center;" | | |- style="background: #4479BA; color: #FFFFFF; text-align: center;" |
| ! rowspan="2" |Diseases | | ! rowspan="2" |Diseases |
| ! colspan="4" |History and Symptoms | | ! colspan="3" |History and Symptoms |
| ! colspan="3" |Physical Examination | | ! colspan="3" |Physical Examination |
| ! colspan="4" |Laboratory Findings | | ! colspan="3" |Laboratory Findings |
| ! rowspan="2" |Other Findings | | ! rowspan="2" |Other Findings |
| |- style="background: #4479BA; color: #FFFFFF; text-align: center;" | | |- style="background: #4479BA; color: #FFFFFF; text-align: center;" |
| !Abdominal Pain | | !Abdominal Pain |
| !Rectal Bleeding | | !Rectal Bleeding |
| !Hyperpigmentation
| |
| !Fatigue | | !Fatigue |
| !Abdominal Tenderness | | !Abdominal Tenderness |
| Line 31: |
Line 28: |
| !Anemia | | !Anemia |
| !Gene(s) | | !Gene(s) |
| !Sertoli Cell Tumors
| |
| !Gastrointestinal Tumors | | !Gastrointestinal Tumors |
| !Cancers | | !Cancers |
| |- | | |- |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Juvenile Polyposis Syndrome''' | | | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Familial Adenomatous Polyposis''' |
| | style="background: #F5F5F5; padding: 5px;" | + | | | style="background: #F5F5F5; padding: 5px; text-align: center;" | + |
| | style="background: #F5F5F5; padding: 5px;" | | | | style="background: #F5F5F5; padding: 5px; text-align: center;" | + |
| | style="background: #F5F5F5; padding: 5px;" | - | | | style="background: #F5F5F5; padding: 5px; text-align: center;" | + |
| | style="background: #F5F5F5; padding: 5px;" | + | | | style="background: #F5F5F5; padding: 5px; text-align: center;" | +/– |
| | style="background: #F5F5F5; padding: 5px;" | - | | | style="background: #F5F5F5; padding: 5px; text-align: center;" | – |
| | style="background: #F5F5F5; padding: 5px;" | - | | | style="background: #F5F5F5; padding: 5px; text-align: center;" | + |
| | style="background: #F5F5F5; padding: 5px;" | - | | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | style="background: #F5F5F5; padding: 5px;" |SMAD4 | | * [[APC (gene)|''APC'' gene]] |
| | | * [[MUTYH|''MUTYH'' gene]] |
| [[BMPR1A]] | | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | style="background: #F5F5F5; padding: 5px;" | - | | * [[Adenoma]]+++ |
| | style="background: #F5F5F5; padding: 5px;" |[[Adenoma]]+ | | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | | * [[Colon (anatomy)|Colon]] |
| [[Hamartoma]]+++ | | * [[Brain]] |
| | style="background: #F5F5F5; padding: 5px;" |[[Colon (anatomy)|Colon]] | | * [[Thyroid]] |
| | style="background: #F5F5F5; padding: 5px;" | | | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | * [[Desmoid tumor]] |
| | * [[Osteoma]] |
| | |- |
| | | style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Peutz-Jeghers syndrome|'''Peutz–Jeghers syndrome''']] |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | + |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | + |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | + |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | + |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | + |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | + |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | |
| | * [[STK11]] (LBK1) gene |
| | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | * [[Adenoma]]+ |
| | * [[Hamartoma]]+++ |
| | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | * [[Breast]] |
| | * [[Lung]] |
| | * [[Pancreas]] |
| | * [[Ovaries]] |
| | * [[Sertoli cell|Sertoli cells]] |
| | * [[Uterus]] |
| | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | |- |
| | | style="background: #DCDCDC; padding: 5px; text-align: center;" |'''[[Juvenile polyposis syndrome|Juvenile Polyposis Syndrome]]''' |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | + |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | + |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | – |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | – |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | – |
| | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | * SMAD4 |
| | * [[BMPR1A]] |
| | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | * [[Adenoma]]+ |
| | * [[Hamartoma]]+++ |
| | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | * [[Colon (anatomy)|Colon]] |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | |
| |- | | |- |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Cowden syndrome|'''Cowden Syndrome''']] | | | style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Cowden syndrome|'''Cowden Syndrome''']] |
| | style="background: #F5F5F5; padding: 5px;" | - | | | style="background: #F5F5F5; padding: 5px; text-align: center;" | – |
| | style="background: #F5F5F5; padding: 5px;" | - | | | style="background: #F5F5F5; padding: 5px; text-align: center;" | – |
| | style="background: #F5F5F5; padding: 5px;" |[[Axillary]]+ | | | style="background: #F5F5F5; padding: 5px; text-align: center;" | – |
| | | | style="background: #F5F5F5; padding: 5px; text-align: center;" | – |
| [[Inguinal region|Inguinal]]+
| | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | | * [[Axillary]]+ [[Inguinal region|Inguinal]]+ [[Facial]]+ |
| [[Facial]]+
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | – |
| | style="background: #F5F5F5; padding: 5px;" | - | | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | style="background: #F5F5F5; padding: 5px;" | - | | * [[PTEN (gene)|PTEN]] |
| | style="background: #F5F5F5; padding: 5px;" |[[Axillary]]+
| | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | | * [[Adenoma]]+ |
| [[Inguinal region|Inguinal]]+ | | * [[Hamartoma]]+++ |
| | | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| [[Facial]]+ | | * [[Breast]] |
| | style="background: #F5F5F5; padding: 5px;" | - | | * [[Thyroid]] |
| | style="background: #F5F5F5; padding: 5px;" |[[PTEN (gene)|PTEN]] | | * [[Endometrium]] |
| | style="background: #F5F5F5; padding: 5px;" | - | | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | style="background: #F5F5F5; padding: 5px;" |[[Adenoma]]+
| | * [[Trichilemmoma]] |
| | | * Skin [[hamartoma]] |
| [[Hamartoma]]+++ | | * [[Colon polyps|Hyperplastic polyp]] |
| | style="background: #F5F5F5; padding: 5px;" |[[Breast]], [[Thyroid]], [[Endometrium]] | | * [[Macrocephaly]] |
| | style="background: #F5F5F5; padding: 5px;" |[[Trichilemmoma]], [[skin]] [[hamartoma]], [[Hyperplasia|hyperplastic]] [[Polyp|polyps]], [[macrocephaly]], [[breast]] [[fibrosis]] | | * Breast [[fibrosis]] |
| |- | | |- |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Carney syndrome|'''Carney Syndrome''']] | | | style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Carney syndrome|'''Carney Syndrome''']] |
| | style="background: #F5F5F5; padding: 5px;" | - | | | style="background: #F5F5F5; padding: 5px; text-align: center;" | – |
| | style="background: #F5F5F5; padding: 5px;" | -
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | – |
| | style="background: #F5F5F5; padding: 5px;" |[[Facial]]+
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | – |
| | | | style="background: #F5F5F5; padding: 5px; text-align: center;" | – |
| [[Mucous membrane|Mucosal]]+
| | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | style="background: #F5F5F5; padding: 5px;" | -
| | * [[Facial]]+ [[Mucous membrane|Mucosal]]+ |
| | style="background: #F5F5F5; padding: 5px;" | -
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | – |
| | style="background: #F5F5F5; padding: 5px;" |[[Facial]]+
| | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | | * [[PRKAR1A]] |
| [[Mucous membrane|Mucosal]]+
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | |
| | style="background: #F5F5F5; padding: 5px;" | -
| | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | style="background: #F5F5F5; padding: 5px;" |[[PRKAR1A]]
| | * [[Thyroid]] |
| | style="background: #F5F5F5; padding: 5px;" | ++
| | * [[Sertoli-Leydig cell tumor|Sertoli Cell]] |
| | style="background: #F5F5F5; padding: 5px;" |
| | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | style="background: #F5F5F5; padding: 5px;" |[[Thyroid]]
| | * Myxoma of [[skin]] |
| | style="background: #F5F5F5; padding: 5px;" |[[Myxoma|Myxomas]] of [[skin]] and [[heart]]
| | * Myxoma of [[heart]] |
| |-
| |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Familial adenomatous polyposis|'''Familial Adenomatous Polyposis''']]
| |
| | style="background: #F5F5F5; padding: 5px;" | +
| |
| | style="background: #F5F5F5; padding: 5px;" | +
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | +
| |
| | style="background: #F5F5F5; padding: 5px;" | +/-
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | +
| |
| | style="background: #F5F5F5; padding: 5px;" |[[APC]] | |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" |[[Adenoma]]+++
| |
| | style="background: #F5F5F5; padding: 5px;" |[[Colon (anatomy)|Colon]], [[brain]]
| |
| | style="background: #F5F5F5; padding: 5px;" |[[Desmoid tumor|Desmoid tumors]], [[Osteoma|osteomas]]
| |
| |-
| |
| | style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hereditary nonpolyposis colorectal cancer|'''Hereditary Non-Polyposis Colon Cancer''']]
| |
| | style="background: #F5F5F5; padding: 5px;" | - | |
| | style="background: #F5F5F5; padding: 5px;" | +
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | +
| |
| | style="background: #F5F5F5; padding: 5px;" | +/-
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" | +
| |
| | style="background: #F5F5F5; padding: 5px;" |[[MLH1]]
| |
| | |
| [[MSH2]]
| |
| | |
| [[MSH3]]
| |
| | |
| [[MSH6]]
| |
| | |
| [[PMS1]]
| |
| | |
| [[PMS2]]
| |
| | style="background: #F5F5F5; padding: 5px;" | -
| |
| | style="background: #F5F5F5; padding: 5px;" |[[Adenoma]]+
| |
| | style="background: #F5F5F5; padding: 5px;" |[[Endometrium|Endometrial]], [[Stomach|gastric]], [[renal pelvis]], [[ureter]], and [[Ovary|ovarian]]
| |
| | style="background: #F5F5F5; padding: 5px;" |[[Sebaceous gland|Sebaceous]] [[adenoma]]
| |
| |}
| |
| | |
| {| align="center"
| |
| |+'''Differential of gastrointestinal bleeding'''
| |
| |-
| |
| |
| |
| {| style="border: 0px; font-size: 90%; margin: 3px;" align="center"
| |
| ! rowspan="3" style="background:#4479BA; color: #FFFFFF;" align="center" |Disease
| |
| | colspan="13" rowspan="1" style="background:#4479BA; color: #FFFFFF;" align="center" |'''Clinical manifestations'''
| |
| ! colspan="2" rowspan="2" style="background:#4479BA; color: #FFFFFF;" align="center" |Diagnosis
| |
| ! rowspan="3" style="background:#4479BA; color: #FFFFFF;" align="center" |Comments
| |
| |-
| |
| | colspan="9" rowspan="1" style="background:#4479BA; color: #FFFFFF;" align="center" |'''Symptoms''' | |
| ! colspan="4" rowspan="1" style="background:#4479BA; color: #FFFFFF;" align="center" | Signs
| |
| |-
| |
| ! style="background:#4479BA; color: #FFFFFF;" align="center" |Abdominal Pain
| |
| ! colspan="1" rowspan="1" style="background:#4479BA; color: #FFFFFF;" align="center" | Fever
| |
| ! style="background:#4479BA; color: #FFFFFF;" align="center" |Rigors and chills
| |
| ! style="background:#4479BA; color: #FFFFFF;" align="center" |Nausea or vomiting
| |
| ! style="background:#4479BA; color: #FFFFFF;" align="center" |Jaundice
| |
| ! style="background:#4479BA; color: #FFFFFF;" align="center" |Constipation
| |
| ! style="background:#4479BA; color: #FFFFFF;" align="center" |Diarrhea
| |
| ! style="background:#4479BA; color: #FFFFFF;" align="center" |Weight loss
| |
| ! style="background:#4479BA; color: #FFFFFF;" align="center" |GI bleeding
| |
| ! style="background:#4479BA; color: #FFFFFF;" align="center" |Hypo-
| |
| tension
| |
| ! colspan="1" rowspan="1" style="background:#4479BA; color: #FFFFFF;" align="center" | Guarding
| |
| ! style="background:#4479BA; color: #FFFFFF;" align="center" |Rebound Tenderness
| |
| ! style="background:#4479BA; color: #FFFFFF;" align="center" |Bowel sounds
| |
| ! colspan="1" rowspan="1" style="background:#4479BA; color: #FFFFFF;" align="center" | Lab Findings
| |
| ! style="background:#4479BA; color: #FFFFFF;" align="center" |Imaging
| |
| |-
| |
| | colspan="1" rowspan="1" style="padding: 5px 5px; background: #DCDCDC;" align="center" |Peutz-Jeghers syndrome
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |Depends on location of polyps it maybe present
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| |
| * Rectal bleeding may be present due to polyp
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| |
| * Hamartomatous polyps present on endoscopy
| |
| * Iron deficiency anemia on CBC
| |
| * STK11 mutation
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | | |
| * Intra-operative enteroscopy (laparatomy with endoscopy
| |
| * Double balloon eneteroscopy
| |
| * Colonoscopy
| |
| * Barium Swallow
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| |
| * Can lead to colon cancer, breast cancer, ovarian cancer, cervical cancer, and testicular cancer
| |
| |-
| |
| | colspan="1" rowspan="1" style="padding: 5px 5px; background: #DCDCDC;" align="center" | [[Peptic Ulcer Disease|Peptic ulcer disease]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |Diffuse
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | <nowiki>+</nowiki>
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | <nowiki>+</nowiki>
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| |
| * Gastric ulcer- [[melena]] and [[hematemesis]]
| |
| * Duodenal ulcer- [[melena]] and [[hematochezia]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | Positive if perforated
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | Positive if perforated
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | Positive if perforated
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |N
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Ascitic fluid
| |
| ** [[LDH]] > serum [[LDH]]
| |
| ** Glucose < 50mg/dl
| |
| ** Total protein > 1g/dl
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Air under [[diaphragm]] in upright [[CXR]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Upper GI [[endoscopy]] for diagnosis
| |
| |-
| |
| | style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Gastritis|Gastritis]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Epigastric]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | <nowiki>+</nowiki>
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | Positive in chronic gastritis
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |N
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * [[H.pylori infection diagnostic tests]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" | | |
| * [[Endoscopy]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * [[H.pylori gastritis guideline recommendation]]
| |
| |-
| |
| | style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Gastrointestinal perforation]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |Diffuse
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ± | |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>-</nowiki>
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |−
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |− | |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |Hyperactive/hypoactive
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * WBC> 10,000
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Air under [[diaphragm]] in upright [[CXR]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * [[Hamman's sign]]
| |
| |-
| |
| | colspan="1" rowspan="1" style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Diverticulitis|Acute diverticulitis]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |LLQ
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |−
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | Positive in perforated diverticulitis
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |Hypoactive
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * [[Leukocytosis]] | |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" | | |
| * CT scan
| |
| * Ultrasound
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * History of [[constipation]]
| |
| |-
| |
| | style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Inflammatory bowel disease]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |Diffuse
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | − | |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |Normal or hyperactive
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * [[Anti-neutrophil cytoplasmic antibody]] ([[P-ANCA]]) in [[Ulcerative colitis]]
| |
| * [[Anti saccharomyces cerevisiae antibodies]] (ASCA) in [[Crohn's disease]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * [[String sign]] on [[abdominal x-ray]] in [[Crohn's disease]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| Extra intestinal findings:
| |
| * [[Uveitis]]
| |
| * [[Arthritis]]
| |
| |-
| |
| | style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Infective colitis]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |Diffuse
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | Positive in fulminant colitis
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |Hyperactive
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * [[Stool culture]] and studies
| |
| * Shiga toxin in bloody diarrhea
| |
| * [[PCR]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |CT scan
| |
| * Bowel wall thickening
| |
| * Edema
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| |-
| |
| | style="padding: 5px 5px; background: #DCDCDC;" align="center" |Colon carcinoma
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |Diffuse/localized
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Normal or hyperactive if obstruction present
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * CBC
| |
| * Carcinoembryonic antigen (CEA)
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Colonoscopy
| |
| * Flexible sigmoidoscopy
| |
| * Barium enema
| |
| * CT colonography
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * PILLCAM 2: A colon capsule for CRC screening may be used in patients with an incomplete colonoscopy who lacks obstruction | |
| |-
| |
| | style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Budd-Chiari syndrome|Budd-Chiari syndrome]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[RUQ]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | Positive in liver failure leading to varices
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |N
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| *Elevated [[Aspartate aminotransferase|serum aspartate aminotransferase]] and [[alanine aminotransferase]] levels may be more than five times the upper limit of the normal range.
| |
| *Elevated serum [[alkaline phosphatase]] and [[Bilirubin|bilirubin levels]], decreased [[Albumin|serum albumin level]]. | |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| {| style="border: 0px; font-size: 90%; margin: 3px;" align="center"
| |
| |-
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |Findings on [[CT scan]] suggestive of Budd-Chiari syndrome include:
| |
| *Early enhancement of the [[caudate lobe]] and [[central liver]] around the [[Inferior vena cavae|inferior vena cava]]
| |
| *Delayed enhancement of the peripheral [[liver]] with accompanying central low density (flip-flop appearance)
| |
| *Peripheral zones of the [[liver]] show reversed [[portal]] [[venous]] [[blood flow]]
| |
| *In the [[chronic]] phase, there is [[caudate lobe]] enlargement and [[atrophy]] of the [[Liver|peripheral liver]] in affected areas
| |
| |}
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |[[Ascitic tap|Ascitic fluid examination]] shows: | |
| *[[Total protein]] more than 2.5 g per deciliter
| |
| *[[White blood cells]] are usually less than 500/μL.
| |
| |-
| |
| | style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Hemochromatosis]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |RUQ
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | Positive in cirrhotic patients
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |N
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * >60% TS
| |
| * >240 μg/L SF
| |
| * Raised LFT <br>Hyperglycemia
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Ultrasound shows evidence of cirrhosis
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |Extra intestinal findings:
| |
| * Hyperpigmentation
| |
| * Diabetes mellitus
| |
| * Arthralgia
| |
| * Impotence in males
| |
| * Cardiomyopathy
| |
| * Atherosclerosis
| |
| * Hypopituitarism
| |
| * Hypothyroidism
| |
| * Extrahepatic cancer
| |
| * Prone to specific infections
| |
| |-
| |
| | style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Cirrhosis|Cirrhosis]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[RUQ]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |N
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * [[Hypoalbuminemia]]
| |
| * Prolonged PT
| |
| * Abnormal LFTs
| |
| * [[Hyponatremia]]
| |
| * [[Thrombocytopenia]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |US
| |
| * Nodular, shrunken liver
| |
| * [[Ascites]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Stigmata of liver disease
| |
| * Cruveilhier- Baumgarten murmur
| |
| |-
| |
| | style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Mesenteric ischemia]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |Periumbilical
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |Positive if bowel becomes gangrenous
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | Positive if bowel becomes gangrenous
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | Positive if bowel becomes gangrenous
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |Hyperactive to absent
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * [[Leukocytosis]] and [[lactic acidosis]] | |
| * [[Amylase]] levels
| |
| * [[D-dimer]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |CT angiography
| |
| * SMA or SMV thrombosis
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Also known as abdominal angina that worsens with eating
| |
| |-
| |
| | style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Ischemic colitis|Acute ischemic colitis]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | Diffuse
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |Hyperactive then absent
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * [[Leukocytosis]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |[[Abdominal x-ray]]
| |
| * Distension and pneumatosis
| |
| CT scan
| |
| * Double halo appearance, thumbprinting
| |
| * Thickening of bowel
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * May lead to shock
| |
| |-
| |
| | style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Ruptured abdominal aortic aneurysm]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | Diffuse
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" |<nowiki>+</nowiki>
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |N
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * [[Fibrinogen]]
| |
| * [[D-dimer]] | |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Focused Assessment with Sonography in Trauma (FAST)
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * Unstable hemodynamics
| |
| |-
| |
| | style="padding: 5px 5px; background: #DCDCDC;" align="center" |Intra-abdominal or [[retroperitoneal hemorrhage]]
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | Diffuse
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="center" | −
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |N
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * ↓ Hb
| |
| * ↓ Hct
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * CT scan
| |
| | style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| |
| * History of [[trauma]]
| |
| |- | | |- |
| |} | | | style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hereditary nonpolyposis colorectal cancer|'''Hereditary Non–Polyposis Colon Cancer''']] |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | – |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | + |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | + |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | +/– |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | – |
| | | style="background: #F5F5F5; padding: 5px; text-align: center;" | + |
| | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | * [[MLH1]] |
| | * [[MSH2]] |
| | * [[MSH3]] |
| | * [[MSH6]] |
| | * [[PMS1]] |
| | * [[PMS2]] |
| | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | * [[Adenoma]]+ |
| | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | * [[Endometrium]] |
| | * [[Stomach]] |
| | * [[Kidney|Kidneys]] |
| | * [[Ureter]] |
| | * [[Ovary|Ovaries]] |
| | | style="background: #F5F5F5; padding: 5px; text-align: left;" | |
| | * [[Sebaceous gland|Sebaceous]] [[adenoma]] |
| |} | | |} |
|
| |
|
| ==References== | | ==References== |
| {{Reflist|2}} | | {{Reflist|2}} |
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|
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|
| | [[Category:Medicine]] |
| [[Category:Gastroenterology]] | | [[Category:Gastroenterology]] |
| [[Category:Genetic disorders]]
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| [[Category:Genetic Disease]]
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| [[Category:Disease]]
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|
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|
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| {{WH}}
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| {{WS}}
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| [[Category:Up-To-Date]]
| |
| [[Category:Oncology]] | | [[Category:Oncology]] |
| [[Category:Medicine]] | | [[Category:Up-To-Date]] |
| [[Category:Gastroenterology]]
| |
