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==Overview==
==Overview==
Deep Vein Thrombosis and [[Pulmonary Embolism]] (DVT/PE) represent a major public health problem, exacting a significant human and  
Deep Vein Thrombosis and [[Pulmonary Embolism]] (DVT/PE) represent a major public health problem, exacting a significant human and  
economic toll on the Nation.It is estimated that approximately 350,000 to 600,000 Americans each year suffer from DVT and pulmonary embolism and at least 100,000 deaths may be directly or indirectly related to these diseases[http://www.ncbi.nlm.nih.gov/pubmed/20669525].
economic toll on the Nation. It is estimated that approximately 350,000 to 600,000 Americans each year suffer from DVT and pulmonary embolism and at least 100,000 deaths may be directly or indirectly related to these diseases[http://www.ncbi.nlm.nih.gov/pubmed/20669525].





Revision as of 17:48, 29 August 2011

Editors-in-Chief: C. Michael Gibson, M.S., M.D. Associate Editor-In-Chief: Ujjwal Rastogi, MBBS [1]

Deep Vein Thrombosis Microchapters

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Epidemiology and Demographics

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Overview

Deep Vein Thrombosis and Pulmonary Embolism (DVT/PE) represent a major public health problem, exacting a significant human and economic toll on the Nation. It is estimated that approximately 350,000 to 600,000 Americans each year suffer from DVT and pulmonary embolism and at least 100,000 deaths may be directly or indirectly related to these diseases[2].


Epidemiology and Demographics

Males have more risk than females and the risk increases with age in both sex.

Caucasians and African Americans have a significantly higher incidence than Hispanics and Asians or Pacific Islanders. [1]

In studies conducted in Worcester, Massachusetts, and Olmsted County, Minnesota, the incidence of VTE was about 1 in 1,000. In both studies, VTE was more common in men; for each 10-year increase in age, the incidence doubled. By extrapolation, it's estimated that more than 250,000 patients are hospitalized annually with VTE.[2]

Over 200,000 new cases of VTE occur annually. Of these, 30 percent die within 30 days, one-fifth suffer sudden death due to PE, and about 30 percent develop recurrent VTE within 10 years. Independent predictors for recurrence include increasing age, obesity, malignant neoplasm and extremity paresis.

DVT is much less common in the pediatric population. About 1 in 100,000 people under the age of 18 experiences deep vein thrombosis, possibly due to

  • Children heartrate being higher than adult
  • Relatively active lifestyle when compared with adults
  • Fewer comorbidities (e.g. malignancy).

References

  1. White RH (2003). "The epidemiology of venous thromboembolism". Circulation. 107 (23 Suppl 1): I4–8. doi:10.1161/01.CIR.0000078468.11849.66. PMID 12814979.
  2. Goldhaber SZ (1998). "Pulmonary embolism". N Engl J Med. 339 (2): 93–104. doi:10.1056/NEJM199807093390207. PMID 9654541.

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