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{{Chronic stable angina}}
{{Chronic stable angina}}
'''Editors-In-Chief:''' [[C. Michael Gibson, M.S., M.D.]] [mailto:mgibson@perfuse.org] Phone:617-632-7753; '''Associate Editor(s)-in-Chief:''' {{CZ}}; Smita Kohli, M.D.; [[Lakshmi Gopalakrishnan]], M.B.B.S.
 
'''Editors-In-Chief:''' [[C. Michael Gibson, M.S., M.D.]] [mailto:mgibson@perfuse.org] Phone:617-632-7753; '''Associate Editor(s)-In-Chief:''' {{CZ}}; Smita Kohli, M.D.; [[Lakshmi Gopalakrishnan|Lakshmi Gopalakrishnan, M.B.B.S.]]


==Overview==
==Overview==
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:*'''Lower doses''' of [[dobutamine]] can also be used to detect [[hibernating myocardium]]. Areas of hibernating myocardium exhibit poor or absent contraction at rest but normal contraction during dobutamine infusion. By comparison, areas damaged by myocardial infarction or fibrosis exhibit no improvement with dobutamine.
:*'''Lower doses''' of [[dobutamine]] can also be used to detect [[hibernating myocardium]]. Areas of hibernating myocardium exhibit poor or absent contraction at rest but normal contraction during dobutamine infusion. By comparison, areas damaged by myocardial infarction or fibrosis exhibit no improvement with dobutamine.


==ACC / AHA Guidelines- Exercise Echocardiography in patients Who Are Able to Exercise (DO NOT EDIT)<ref name="pmid10351980">Gibbons RJ, Chatterjee K, Daley J, Douglas JS, Fihn SD, Gardin JM et al. (1999) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=10351980 ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina: executive summary and recommendations. A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Chronic Stable Angina).] ''Circulation'' 99 (21):2829-48. PMID: [http://pubmed.gov/10351980 10351980]</ref>==
==ACC / AHA Guidelines- Exercise Echocardiography in patients Who Are Able to Exercise (DO NOT EDIT) <ref name="pmid10351980">Gibbons RJ, Chatterjee K, Daley J, Douglas JS, Fihn SD, Gardin JM et al. (1999) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=10351980 ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina: executive summary and recommendations. A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Chronic Stable Angina).] ''Circulation'' 99 (21):2829-48. PMID: [http://pubmed.gov/10351980 10351980]</ref>==
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===Class I===
===[[ACC AHA guidelines classification scheme#Classification of Recommendations|Class I]]===
'''1.''' [[Chronic stable angina myocardial perfusion scintigraphy|Exercise myocardial perfusion imaging]] or exercise echocardiography in patients with an intermediate pretest probability of [[CAD]] who have 1 of the following baseline [[Chronic stable angina electrocardiography|ECG]] abnormalities:
'''1.''' [[Chronic stable angina myocardial perfusion scintigraphy|Exercise myocardial perfusion imaging]] or exercise echocardiography in patients with an [[Chronic stable angina assessing the pretest probability of coronary artery disease|intermediate pretest probability]] of [[CAD]] who have 1 of the following baseline [[Chronic stable angina electrocardiography|ECG]] abnormalities:
:a. Preexcitation ([[Wolff-Parkinson-White syndrome|Wolff-Parkinson-White]]) syndrome. ''(Level of Evidence: B)''
:'''a.''' Preexcitation ([[Wolff-Parkinson-White syndrome|Wolff-Parkinson-White]]) syndrome. ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: B]])''
:b. More than 1 mm of rest [[ST depression]]. ''(Level of Evidence: B)''
:'''b.''' More than 1 mm of rest [[ST depression]]. ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: B]])''


'''2.''' [[Chronic stable angina myocardial perfusion scintigraphy|Exercise myocardial perfusion imaging]] or exercise echocardiography in patients with prior [[revascularization]] (either [[percutaneous transluminal coronary angioplasty]] ([[PTCA]]) or [[coronary artery bypass graft]] ([[CABG]]). ''(Level of Evidence: B)''
'''2.''' [[Chronic stable angina myocardial perfusion scintigraphy|Exercise myocardial perfusion imaging]] or exercise echocardiography in patients with prior [[Chronic stable angina revascularization|revascularization]] (either [[Chronic stable angina revascularization percutaneous coronary intervention(PCI)|percutaneous transluminal coronary angioplasty]] (PTCA) or [[Chronic stable angina revascularization coronary artery bypass grafting(CABG)|coronary artery bypass graft]] (CABG). ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: B]])''


===Class IIb===
===[[ACC AHA guidelines classification scheme#Classification of Recommendations|Class IIb]]===
'''1.''' [[Chronic stable angina myocardial perfusion scintigraphy|Exercise myocardial perfusion imaging]] and exercise echocardiography in patients with a low or high probability of [[CAD]] who have 1 of the following baseline [[Chronic stable angina electrocardiography|ECG]] abnormalities:
'''1.''' [[Chronic stable angina myocardial perfusion scintigraphy|Exercise myocardial perfusion imaging]] and exercise echocardiography in patients with a [[Chronic stable angina assessing the pretest probability of coronary artery disease|low or high probability]] of [[CAD]] who have 1 of the following baseline [[Chronic stable angina electrocardiography|ECG]] abnormalities:
:a. Preexcitation ([[Wolff-Parkinson-White|Wolff-Parkinson-White]]) syndrome. ''(Level of Evidence: B)''
:'''a.''' Preexcitation ([[Wolff-Parkinson-White|Wolff-Parkinson-White]]) syndrome. ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: B]])''
:b. More than 1 mm of ST depression. ''(Level of Evidence: B)''
:'''b.''' More than 1 mm of [[ST depression]]. ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: B]])''


'''2.''' [[Chronic stable angina myocardial perfusion scintigraphy|Exercise myocardial perfusion imaging]] or exercise echocardiography in patients with an [[Chronic stable angina assessing the pretest probability of coronary artery disease|intermediate probability of CAD]] who have 1 of the following:
'''2.''' [[Chronic stable angina myocardial perfusion scintigraphy|Exercise myocardial perfusion imaging]] or exercise echocardiography in patients with an [[Chronic stable angina assessing the pretest probability of coronary artery disease|intermediate probability of CAD]] who have 1 of the following:
:a. [[Digoxin]] use with less than 1 mm [[ST depression]] on their baseline [[Chronic stable angina electrocardiography|ECG]]. ''(Level of Evidence: B)''
:'''a.''' [[Digoxin]] use with less than 1 mm [[ST depression]] on their baseline [[Chronic stable angina electrocardiography|ECG]]. ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: B]])''
:b. [[LV hypertrophy]] with less than 1 mm ST depression on their baseline [[Chronic stable angina electrocardiography|ECG]]. ''(Level of Evidence: B)''
:b. [[LV hypertrophy]] with less than 1 mm ST depression on their baseline [[Chronic stable angina electrocardiography|ECG]]. ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: B]])''


'''3.''' [[Chronic stable angina myocardial perfusion scintigraphy|Exercise myocardial perfusion imaging]], exercise echocardiography, [[Chronic stable angina perfusion scintigraphy with pharmacologic stress|adenosine or dipyridamole myocardial perfusion imaging]], or [[dobutamine]] echocardiography as the initial stress test in a patient with a normal [[Chronic stable angina electrocardiography|rest ECG]] who is not taking [[digoxin]]. ''(Level of Evidence: B)''
'''3.''' [[Chronic stable angina myocardial perfusion scintigraphy|Exercise myocardial perfusion imaging]], exercise echocardiography, [[Chronic stable angina perfusion scintigraphy with pharmacologic stress|adenosine or dipyridamole myocardial perfusion imaging]], or [[dobutamine]] echocardiography as the initial stress test in a patient with a normal [[Chronic stable angina electrocardiography|rest ECG]] who is not taking [[digoxin]]. ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: B]])''


'''4.''' Exercise or [[dobutamine]] echocardiography in patients with [[left bundle-branch block]]. ''(Level of Evidence: C)''}}
'''4.''' Exercise or [[dobutamine]] echocardiography in patients with [[left bundle-branch block]]. ''([[ACC AHA guidelines classification scheme#Level of Evidence|Level of Evidence: C]])''}}


==ESC Guidelines for the use of exercise stress with imaging techniques (either echocardiography or perfusion) in the initial diagnostic assessment of angina (DO NOT EDIT)<ref name="pmid16735367">{{cite journal| author=Fox K, Garcia MA, Ardissino D, Buszman P, Camici PG, Crea F et al.| title=Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology. | journal=Eur Heart J | year= 2006 | volume= 27 | issue= 11 | pages= 1341-81 | pmid=16735367 | doi=10.1093/eurheartj/ehl001 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16735367  }} </ref>==
==ESC Guidelines- Exercise stress with imaging techniques (either echocardiography or perfusion) in the initial diagnostic assessment of angina (DO NOT EDIT) <ref name="pmid16735367">{{cite journal| author=Fox K, Garcia MA, Ardissino D, Buszman P, Camici PG, Crea F et al.| title=Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology. | journal=Eur Heart J | year= 2006 | volume= 27 | issue= 11 | pages= 1341-81 | pmid=16735367 | doi=10.1093/eurheartj/ehl001 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16735367  }} </ref>==
{{cquote|
{{cquote|
===Class I===
===[[European society of cardiology#Classes of Recommendations|Class I]]===
'''1.''' Patients with [[Chronic stable angina electrocardiography|resting ECG]] abnormalities, [[LBBB]], more than 1 mm [[ST depression]], paced rhythm, or [[WPW]] which prevent accurate interpretation of [[Chronic stable angina exercise electrocardiography|ECG]] changes during stress. ''(Level of Evidence: B)''
'''1.''' Patients with [[Chronic stable angina electrocardiography|resting ECG]] abnormalities, [[LBBB]], more than 1 mm [[ST depression]], paced rhythm, or [[WPW]] which prevent accurate interpretation of [[Chronic stable angina exercise electrocardiography|ECG]] changes during stress. ''([[European society of cardiology#Level of Evidence|Level of Evidence: B]])''


'''2.''' Patients with a non-conclusive [[Chronic stable angina exercise electrocardiography|exercise ECG]] but reasonable exercise tolerance, who do not have a [[Chronic stable angina assessing the pretest probability of coronary artery disease|high probability]] of significant [[coronary artery disease]] and in whom the diagnosis is still in doubt. ''(Level of Evidence: B)''
'''2.''' Patients with a non-conclusive [[Chronic stable angina exercise electrocardiography|exercise ECG]] but reasonable exercise tolerance, who do not have a [[Chronic stable angina assessing the pretest probability of coronary artery disease|high probability]] of significant [[coronary artery disease]] and in whom the diagnosis is still in doubt. ''([[European society of cardiology#Level of Evidence|Level of Evidence: B]])''


===Class IIa===
===[[European society of cardiology#Classes of Recommendations|Class IIa]]===
'''1.''' Patients with prior [[revascularization]] ([[PCI]] or [[CABG]]) in whom localization of [[ischaemia]] is important. ''(Level of Evidence: B)''
'''1.''' Patients with prior [[Chronic stable angina revascularization|revascularization]] ([[Chronic stable angina revascularization percutaneous coronary intervention(PCI)|PCI]] or [[Chronic stable angina revascularization coronary artery bypass grafting(CABG)|CABG]]) in whom localization of [[ischaemia]] is important. ''([[European society of cardiology#Level of Evidence|Level of Evidence: B]])''


'''2.''' As an alternative to [[Chronic stable angina exercise electrocardiography|exercise ECG]] in patients where facilities, cost, and personnel resources allow. ''(Level of Evidence: B)''
'''2.''' As an alternative to [[Chronic stable angina exercise electrocardiography|exercise ECG]] in patients where facilities, cost, and personnel resources allow. ''([[European society of cardiology#Level of Evidence|Level of Evidence: B]])''


'''3.''' As an alternative to [[Chronic stable angina exercise electrocardiography|exercise ECG]] in patients with a [[Chronic stable angina assessing the pretest probability of coronary artery disease|low pre-test probability]] of disease such as women with [[chest pain|atypical chest pain]]. ''(Level of Evidence: B)''
'''3.''' As an alternative to [[Chronic stable angina exercise electrocardiography|exercise ECG]] in patients with a [[Chronic stable angina assessing the pretest probability of coronary artery disease|low pre-test probability]] of disease such as women with [[chest pain|atypical chest pain]]. ''([[European society of cardiology#Level of Evidence|Level of Evidence: B]])''


'''4.''' To assess functional severity of intermediate lesions on [[Chronic stable angina coronary angiography|coronary arteriography]]. ''(Level of Evidence: C)''
'''4.''' To assess functional severity of intermediate lesions on [[Chronic stable angina coronary angiography|coronary arteriography]]. ''([[European society of cardiology#Level of Evidence|Level of Evidence: C]])''


'''5.''' To localize [[ischaemia]] when planning [[revascularization]] options in patients who have already had [[Chronic stable angina coronary angiography|arteriography]]. ''(Level of Evidence: B)''}}
'''5.''' To localize [[ischaemia]] when planning [[revascularization]] options in patients who have already had [[Chronic stable angina coronary angiography|arteriography]]. ''([[European society of cardiology#Level of Evidence|Level of Evidence: B]])''}}


==Vote on and Suggest Revisions to the Current Guidelines==
==Vote on and Suggest Revisions to the Current Guidelines==
Line 76: Line 77:


==Sources==
==Sources==
*The ACC/AHA/ACP–ASIM Guidelines for the Management of Patients With Chronic Stable Angina <ref name="pmid10351980">Gibbons RJ, Chatterjee K, Daley J, Douglas JS, Fihn SD, Gardin JM et al. (1999) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=10351980 ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina: executive summary and recommendations. A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Chronic Stable Angina).] ''Circulation'' 99 (21):2829-48. [http://circ.ahajournals.org/content/99/21/2829.full.pdf] PMID: [http://pubmed.gov/10351980 10351980]</ref>
*Guidelines on the management of stable angina pectoris: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology <ref name="pmid16735367">{{cite journal| author=Fox K, Garcia MA, Ardissino D, Buszman P, Camici PG, Crea F et al.| title=Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology. | journal=Eur Heart J | year= 2006 | volume= 27 | issue= 11 | pages= 1341-81 | pmid=16735367 | doi=10.1093/eurheartj/ehl001 | pmc= |url=url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16735367 [http://www.escardio.org/guidelines-surveys/esc-guidelines/GuidelinesDocuments/guidelines-angina-FT.pdf]}} </ref>
*Guidelines on the management of stable angina pectoris: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology <ref name="pmid16735367">{{cite journal| author=Fox K, Garcia MA, Ardissino D, Buszman P, Camici PG, Crea F et al.| title=Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology. | journal=Eur Heart J | year= 2006 | volume= 27 | issue= 11 | pages= 1341-81 | pmid=16735367 | doi=10.1093/eurheartj/ehl001 | pmc= |url=url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16735367 [http://www.escardio.org/guidelines-surveys/esc-guidelines/GuidelinesDocuments/guidelines-angina-FT.pdf]}} </ref>
*The ACC/AHA/ACP–ASIM Guidelines for the Management of Patients With Chronic Stable Angina <ref name="pmid10351980">Gibbons RJ, Chatterjee K, Daley J, Douglas JS, Fihn SD, Gardin JM et al. (1999) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=10351980 ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina: executive summary and recommendations. A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Chronic Stable Angina).] ''Circulation'' 99 (21):2829-48. [http://circ.ahajournals.org/content/99/21/2829.full.pdf] PMID: [http://pubmed.gov/10351980 10351980]</ref>


*TheACC/AHA 2002 Guideline Update for the Management of Patients With Chronic Stable Angina <ref name="pmid12515758">Gibbons RJ, Abrams J, Chatterjee K, Daley J, Deedwania PC, Douglas JS et al. (2003) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=12515758 ACC/AHA 2002 guideline update for the management of patients with chronic stable angina--summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Chronic Stable Angina).] ''Circulation'' 107 (1):149-58.[http://content.onlinejacc.org/cgi/reprint/41/1/159.pdf] PMID: [http://pubmed.gov/12515758 12515758]</ref>
*TheACC/AHA 2002 Guideline Update for the Management of Patients With Chronic Stable Angina <ref name="pmid12515758">Gibbons RJ, Abrams J, Chatterjee K, Daley J, Deedwania PC, Douglas JS et al. (2003) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=12515758 ACC/AHA 2002 guideline update for the management of patients with chronic stable angina--summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Chronic Stable Angina).] ''Circulation'' 107 (1):149-58.[http://content.onlinejacc.org/cgi/reprint/41/1/159.pdf] PMID: [http://pubmed.gov/12515758 12515758]</ref>

Revision as of 18:41, 25 August 2011

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Editors-In-Chief: C. Michael Gibson, M.S., M.D. [3] Phone:617-632-7753; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [4]; Smita Kohli, M.D.; Lakshmi Gopalakrishnan, M.B.B.S.

Overview

Stress echocardiography is echocardiography with different stressors such as exercise or pharmacological with adenosine or dipyridamole or dobutamine. In patients who are unable to exercise pharmacological stress echocardiography is a useful alternative.

Exercise echocardiography appears to be more sensitive, more specific and have a higher predictive value in comparison to exercise ECG. Exercise echocardiography is helpful in the evaluation of regional wall motion response, location and extent of ischemia during stress in patients with MI. During exercise, the normal myocardium is hyperdynamic while in patients with MI, the ischemic myocardium is either akinetic or hypokinetic.

Advantages of stress echocardiography

  • Detection of CAD and in patients with known or suspected CAD, assessing the prognosis of CAD.
  • Stress echocardiography is a more specific test for the assessment of myocardial viability after acute MI [1].
  • In patients with chronic ischemic LV dysfunction, prediction of full functional recovery of the myocardium after revascularisation [2].
  • The capability of stress echocardiography to detect ischemia earlier in the ischemic cascade [3] [4] has been greatly improved with the advent of tissue Doppler imaging [5] and strain rate imaging [6] [7].
  • Tissue Doppler imaging is useful in the quantification of myocardial wall motion and strain.
  • Strain rate imaging is useful to determine regional deformation and strain being the difference per unit length.

Diagnostic criteria

  • The signs suggestive of severe CAD on exercise echocardiography include:
  • reduction on global systolic function,
  • LV dilation,
  • new or progressively worsening MR

Sensitivity and Specificity

  • Exercise echocardiography has been reported to have a sensitivity of 74% to 100% and a specificity of 64% to 93% for detecting CAD.
  • The sensitivity and specificity of exercise echocardiography based on a meta-analysis is 80-85% and 84-86% respectively [8].
  • With the use of high dose of dobutamine (up to 50 gm / kg / min), a method of dobutamine stress echocardiography can be performed with 86% to 96% of sensitivity and 66% to 95% of specificity.
  • Lower doses of dobutamine can also be used to detect hibernating myocardium. Areas of hibernating myocardium exhibit poor or absent contraction at rest but normal contraction during dobutamine infusion. By comparison, areas damaged by myocardial infarction or fibrosis exhibit no improvement with dobutamine.

ACC / AHA Guidelines- Exercise Echocardiography in patients Who Are Able to Exercise (DO NOT EDIT) [9]

Class I

1. Exercise myocardial perfusion imaging or exercise echocardiography in patients with an intermediate pretest probability of CAD who have 1 of the following baseline ECG abnormalities:

a. Preexcitation (Wolff-Parkinson-White) syndrome. (Level of Evidence: B)
b. More than 1 mm of rest ST depression. (Level of Evidence: B)

2. Exercise myocardial perfusion imaging or exercise echocardiography in patients with prior revascularization (either percutaneous transluminal coronary angioplasty (PTCA) or coronary artery bypass graft (CABG). (Level of Evidence: B)

Class IIb

1. Exercise myocardial perfusion imaging and exercise echocardiography in patients with a low or high probability of CAD who have 1 of the following baseline ECG abnormalities:

a. Preexcitation (Wolff-Parkinson-White) syndrome. (Level of Evidence: B)
b. More than 1 mm of ST depression. (Level of Evidence: B)

2. Exercise myocardial perfusion imaging or exercise echocardiography in patients with an intermediate probability of CAD who have 1 of the following:

a. Digoxin use with less than 1 mm ST depression on their baseline ECG. (Level of Evidence: B)
b. LV hypertrophy with less than 1 mm ST depression on their baseline ECG. (Level of Evidence: B)

3. Exercise myocardial perfusion imaging, exercise echocardiography, adenosine or dipyridamole myocardial perfusion imaging, or dobutamine echocardiography as the initial stress test in a patient with a normal rest ECG who is not taking digoxin. (Level of Evidence: B)

4. Exercise or dobutamine echocardiography in patients with left bundle-branch block. (Level of Evidence: C)

ESC Guidelines- Exercise stress with imaging techniques (either echocardiography or perfusion) in the initial diagnostic assessment of angina (DO NOT EDIT) [10]

Class I

1. Patients with resting ECG abnormalities, LBBB, more than 1 mm ST depression, paced rhythm, or WPW which prevent accurate interpretation of ECG changes during stress. (Level of Evidence: B)

2. Patients with a non-conclusive exercise ECG but reasonable exercise tolerance, who do not have a high probability of significant coronary artery disease and in whom the diagnosis is still in doubt. (Level of Evidence: B)

Class IIa

1. Patients with prior revascularization (PCI or CABG) in whom localization of ischaemia is important. (Level of Evidence: B)

2. As an alternative to exercise ECG in patients where facilities, cost, and personnel resources allow. (Level of Evidence: B)

3. As an alternative to exercise ECG in patients with a low pre-test probability of disease such as women with atypical chest pain. (Level of Evidence: B)

4. To assess functional severity of intermediate lesions on coronary arteriography. (Level of Evidence: C)

5. To localize ischaemia when planning revascularization options in patients who have already had arteriography. (Level of Evidence: B)

Vote on and Suggest Revisions to the Current Guidelines

Sources

  • The ACC/AHA/ACP–ASIM Guidelines for the Management of Patients With Chronic Stable Angina [9]
  • Guidelines on the management of stable angina pectoris: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology [10]
  • TheACC/AHA 2002 Guideline Update for the Management of Patients With Chronic Stable Angina [11]
  • The 2007 Chronic Angina Focused Update of the ACC/AHA 2002 Guidelines for the Management of Patients With Chronic Stable Angina [12]

References

  1. Anselmi M, Golia G, Maines M, Marino P, Goj C, Turri M et al. (2000) Comparison between low-dose dobutamine echocardiography and thallium-201 scintigraphy in the detection of myocardial viability in patients with recent myocardial infarction. Int J Cardiol 73 (3):213-23. PMID: 10841962
  2. Bax JJ, Visser FC, Poldermans D, Elhendy A, Cornel JH, Boersma E et al. (2001) Time course of functional recovery of stunned and hibernating segments after surgical revascularization. Circulation 104 (12 Suppl 1):I314-8. PMID: 11568075
  3. Mädler CF, Payne N, Wilkenshoff U, Cohen A, Derumeaux GA, Piérard LA et al. (2003) Non-invasive diagnosis of coronary artery disease by quantitative stress echocardiography: optimal diagnostic models using off-line tissue Doppler in the MYDISE study. Eur Heart J 24 (17):1584-94. PMID: 12927194
  4. Yip G, Khandheria B, Belohlavek M, Pislaru C, Seward J, Bailey K et al. (2004) Strain echocardiography tracks dobutamine-induced decrease in regional myocardial perfusion in nonocclusive coronary stenosis. J Am Coll Cardiol 44 (8):1664-71. DOI:10.1016/j.jacc.2004.02.065 PMID: 15489101
  5. Cain P, Baglin T, Case C, Spicer D, Short L, Marwick TH (2001) Application of tissue Doppler to interpretation of dobutamine echocardiography and comparison with quantitative coronary angiography. Am J Cardiol 87 (5):525-31. PMID: 11230833
  6. Voigt JU, Exner B, Schmiedehausen K, Huchzermeyer C, Reulbach U, Nixdorff U et al. (2003) Strain-rate imaging during dobutamine stress echocardiography provides objective evidence of inducible ischemia. Circulation 107 (16):2120-6. DOI:10.1161/01.CIR.0000065249.69988.AA PMID: 12682001
  7. Yip G, Abraham T, Belohlavek M, Khandheria BK (2003) Clinical applications of strain rate imaging. J Am Soc Echocardiogr 16 (12):1334-42. DOI:10.1067/j.echo.2003.09.004 PMID: 14652617
  8. Schinkel AF, Bax JJ, Geleijnse ML, Boersma E, Elhendy A, Roelandt JR et al. (2003) Noninvasive evaluation of ischaemic heart disease: myocardial perfusion imaging or stress echocardiography? Eur Heart J 24 (9):789-800. PMID: 12727146
  9. 9.0 9.1 Gibbons RJ, Chatterjee K, Daley J, Douglas JS, Fihn SD, Gardin JM et al. (1999) ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina: executive summary and recommendations. A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Chronic Stable Angina). Circulation 99 (21):2829-48. PMID: 10351980
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