Chancroid differential diagnosis: Difference between revisions

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{{Chancroid}}
{{Chancroid}}
{{CMG}}; {{AE}} {{YD}}; {{NRM}}; {{SSK}}


==Overview==
==Overview==
Chancroid must be differentiated from other diseases that cause genital ulcers and lymphadenopathy including syphilis, herpes simplex, dermatologic aspects of Behçet's disease, dermatologic manifestations of Lymphogranuloma venereum, donovanosis, and fixed drug eruption.
Chancroid must be differentiated from other diseases that cause genital [[ulcers]] and [[lymphadenopathy]] including [[syphilis]], [[herpes simplex]], [[Behçet's disease]], [[lymphogranuloma venereum]], [[donovanosis]], and [[fixed drug eruption]].


==Differential Diagnosis of Chancroid==
==Differentiating Chancroid from Other Diseases==
Chancroid must be differentiated from other diseases that cause genital ulcers and lymphadenopathy:
Chancroid must be differentiated from other diseases that cause [[Genital ulcer disease|genital ulcers]] and [[lymphadenopathy]]:
*[[Syphilis]]
*[[Syphilis]]
*[[Herpes simplex]]
*[[Herpes simplex]]
*Dermatologic aspects of [[Behçet's disease]]
*[[Behçet's disease]]
*Dermatologic manifestations of [[Lymphogranuloma venereum]]
*[[Lymphogranuloma venereum]]
*[[Donovanosis]]
*[[Donovanosis]]
*[[Fixed drug eruption]]
*[[Fixed drug eruption]]
*[[Psoriasis]]


Syphilitic chancres most closely resemble and chancroid lesion. A comparison is found below:<ref name="ChancroidWikipedia">Chancroid. Wikipedia (July 16, 2015). https://en.wikipedia.org/wiki/Chancroid Accessed January 15, 2015.</ref>
Syphilitic chancres most closely resemble chancroid lesions. A comparison is found below:<ref name="ChancroidWikipedia">Chancroid. Wikipedia (July 16, 2015). https://en.wikipedia.org/wiki/Chancroid Accessed January 15, 2016.</ref>
{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
{| style="font-size: 90%;"
! style="background: #4479BA; padding: 5px 5px;" rowspan=2 | {{fontcolor|#FFFFFF|Clinical Characteristic}}
! style="background: #4479BA; padding: 5px 5px;" rowspan=2 | {{fontcolor|#FFFFFF|Clinical Characteristic}}
! style="background: #4479BA; padding: 5px 5px;" colspan=2 | {{fontcolor|#FFFFFF|Disease}}
! style="background: #4479BA; padding: 5px 5px;" colspan=2 | {{fontcolor|#FFFFFF|Disease}}
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! style="background: #4479BA; padding: 5px 5px;" | {{fontcolor|#FFFFFF|Chancroid}}
! style="background: #4479BA; padding: 5px 5px;" | {{fontcolor|#FFFFFF|Chancroid}}
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold;" | Mode of Transmission
| style="padding: 5px 5px; background: #DCDCDC;" | '''Mode of Transmission'''
! style="padding: 5px 5px; background: #F5F5F5;" | Mainly sexual
| style="padding: 5px 5px; background: #F5F5F5;" | Mainly sexual
! style="padding: 5px 5px; background: #F5F5F5;" | Mainly sexual
| style="padding: 5px 5px; background: #F5F5F5;" | Mainly sexual
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold;" | Cause
| style="padding: 5px 5px; background: #DCDCDC;" | '''Cause'''
! style="padding: 5px 5px; background: #F5F5F5;" | ''Treponema pallidum''
| style="padding: 5px 5px; background: #F5F5F5;" | ''Treponema pallidum''
! style="padding: 5px 5px; background: #F5F5F5;" | ''Haemophilus ducreyi''
| style="padding: 5px 5px; background: #F5F5F5;" | ''Haemophilus ducreyi''
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold;" | Lesion Type
| style="padding: 5px 5px; background: #DCDCDC;" | '''Lesion Type'''
! style="padding: 5px 5px; background: #F5F5F5;" | Pustules that may progress to ulcers
| style="padding: 5px 5px; background: #F5F5F5;" | Pustules that may progress to ulcers
! style="padding: 5px 5px; background: #F5F5F5;" | Pustules that may progress to ulcers
| style="padding: 5px 5px; background: #F5F5F5;" | Pustules that may progress to ulcers
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold;" | Lesion Pain
| style="padding: 5px 5px; background: #DCDCDC;" | '''Lesion Pain'''
! style="padding: 5px 5px; background: #F5F5F5;" | Typically absent
| style="padding: 5px 5px; background: #F5F5F5;" | Typically absent
! style="padding: 5px 5px; background: #F5F5F5;" | Typically present
| style="padding: 5px 5px; background: #F5F5F5;" | Typically present
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold;" | Lesion Location
| style="padding: 5px 5px; background: #DCDCDC;" | '''Lesion Location'''
! style="padding: 5px 5px; background: #F5F5F5;" | Typically genitals
| style="padding: 5px 5px; background: #F5F5F5;" | Typically genitals
! style="padding: 5px 5px; background: #F5F5F5;" | Typically genitals; may occur on limbs
| style="padding: 5px 5px; background: #F5F5F5;" | Typically genitals; may occur on limbs
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold;" | Lesion Size
| style="padding: 5px 5px; background: #DCDCDC;" | '''Lesion Size'''
! style="padding: 5px 5px; background: #F5F5F5;" | Typically 1-2 cm in diameter
| style="padding: 5px 5px; background: #F5F5F5;" | Typically 1-2 cm in diameter
! style="padding: 5px 5px; background: #F5F5F5;" | Typically 1-2 cm in diameter
| style="padding: 5px 5px; background: #F5F5F5;" | Typically 1-2 cm in diameter
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold;" | Lesion Number
| style="padding: 5px 5px; background: #DCDCDC;" | '''Lesion Number'''
! style="padding: 5px 5px; background: #F5F5F5;" | Multiple
| style="padding: 5px 5px; background: #F5F5F5;" | Multiple
! style="padding: 5px 5px; background: #F5F5F5;" | 1-4
| style="padding: 5px 5px; background: #F5F5F5;" | 1-4
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold;" | Lesion Exudate
| style="padding: 5px 5px; background: #DCDCDC;" | '''Lesion Exudate'''
! style="padding: 5px 5px; background: #F5F5F5;" | Typically non-exudative
| style="padding: 5px 5px; background: #F5F5F5;" | Typically non-exudative
! style="padding: 5px 5px; background: #F5F5F5;" | Typically grey/yellow purulent exudate
| style="padding: 5px 5px; background: #F5F5F5;" | Typically grey/yellow purulent exudate
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold;" | Lesion Tenderness
| style="padding: 5px 5px; background: #DCDCDC;" | '''Lesion Texture'''
! style="padding: 5px 5px; background: #F5F5F5;" | Typically indurated
| style="padding: 5px 5px; background: #F5F5F5;" | Typically indurated
! style="padding: 5px 5px; background: #F5F5F5;" | Typically soft
| style="padding: 5px 5px; background: #F5F5F5;" | Typically soft
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold;" | lymphadenopathy
| style="padding: 5px 5px; background: #DCDCDC;" | '''Lymphadenopathy'''
! style="padding: 5px 5px; background: #F5F5F5;" | Typically present
| style="padding: 5px 5px; background: #F5F5F5;" | Typically present
! style="padding: 5px 5px; background: #F5F5F5;" | Occurs in approx. half of patients
| style="padding: 5px 5px; background: #F5F5F5;" | Occurs in approx. half of patients
|}
|}


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{{Reflist|2}}
{{Reflist|2}}


[[Category:Needs content]]
[[Category:Disease]]
[[Category:Disease]]
[[Category:Sexually transmitted diseases]]
[[Category:Sexually transmitted diseases]]
[[Category:Bacterial diseases]]
[[Category:Bacterial diseases]]
[[Category:Proteobacteria]]
[[Category:Proteobacteria]]
[[Category:Infectious disease]]
 


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Latest revision as of 17:21, 18 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Nate Michalak, B.A.; Serge Korjian M.D.

Overview

Chancroid must be differentiated from other diseases that cause genital ulcers and lymphadenopathy including syphilis, herpes simplex, Behçet's disease, lymphogranuloma venereum, donovanosis, and fixed drug eruption.

Differentiating Chancroid from Other Diseases

Chancroid must be differentiated from other diseases that cause genital ulcers and lymphadenopathy:

Syphilitic chancres most closely resemble chancroid lesions. A comparison is found below:[1]

Clinical Characteristic Disease
Syphilitic Chancre Chancroid
Mode of Transmission Mainly sexual Mainly sexual
Cause Treponema pallidum Haemophilus ducreyi
Lesion Type Pustules that may progress to ulcers Pustules that may progress to ulcers
Lesion Pain Typically absent Typically present
Lesion Location Typically genitals Typically genitals; may occur on limbs
Lesion Size Typically 1-2 cm in diameter Typically 1-2 cm in diameter
Lesion Number Multiple 1-4
Lesion Exudate Typically non-exudative Typically grey/yellow purulent exudate
Lesion Texture Typically indurated Typically soft
Lymphadenopathy Typically present Occurs in approx. half of patients

References

  1. Chancroid. Wikipedia (July 16, 2015). https://en.wikipedia.org/wiki/Chancroid Accessed January 15, 2016.


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