Blalock-Taussig shunt: Difference between revisions

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* The classic or original BT shunt procedure was named after [[Alfred Blalock]], surgeon, Baltimore, (1899–1964) and [[Helen B. Taussig]], cardiologist, Baltimore/Boston, (1898–1986) who, along with Blalock's African American laboratory technician [[Vivien Thomas]] (1910–1985), developed and described the procedure.  
* The classic or original BT shunt procedure was named after [[Alfred Blalock]], surgeon, Baltimore, (1899–1964) and [[Helen B. Taussig]], cardiologist, Baltimore/Boston, (1898–1986) who, along with Blalock's African American laboratory technician [[Vivien Thomas]] (1910–1985), developed and described the procedure.  
* Taussig noticed that the children with cyanosis along with [[congenital heart disease]] accompanied by [[patent ductus arteriosus]] have longer life time than those without PDA.  
* Taussig noticed that the children with cyanosis along with [[congenital heart disease]] accompanied by [[patent ductus arteriosus]] have longer life time than those without [[Patent ductus arteriosus|PDA]].
*Dr. Taussig approached Blalock and Thomas in their Hopkins laboratory in 1943 to work upon in this shunt as it was hypothesized that a shunt mimicking [[PDA]] can relieve the cyanosis and improve [[oxygenation]] in [[congential cyanotic diseases]].<ref>https://www.upenn.edu/pennpress/book/1904.html</ref>
*In 1943, Dr. Taussig approached Blalock and Thomas in their Hopkins laboratory to work on this shunt as it was hypothesized that a shunt mimicking [[PDA]] can relieve the cyanosis and improve [[oxygenation]] in [[congential cyanotic diseases]].<ref>https://www.upenn.edu/pennpress/book/1904.html</ref>


[[File:Original-blalock-taussig-shunt-creative-commons.png|thumb|200px|none|Original Blalock-Taussig shunt diagram. [https://radiopaedia.org/cases/74774 Source: Dr Laurent Bilodeau.]]]
[[File:Original-blalock-taussig-shunt-creative-commons.png|thumb|200px|none|Original Blalock-Taussig shunt diagram. [https://radiopaedia.org/cases/74774 Source: Dr Laurent Bilodeau.]]]


=== Modified Blalock-Taussig Shunt ===
=== Modified Blalock-Taussig Shunt ===
*A modified method of inserting a shunt was developed in 1962  by Klinner using [[teflon]] as [[Prosthetic|prosthetic graft]] material between the [[subclavian artery]] and the [[pulmonary artery]] is used to prevent [[scarring]] of the [[subclavian artery]].<ref name="pmid144570412">{{cite journal| author=KLINNER W, PASINI M, SCHAUDIG A| title=[Anastomosis between systemic and pulmonary arteries with the aid of plastic prostheses in cyanotic heart diseases]. | journal=Thoraxchirurgie | year= 1962 | volume= 10 | issue=  | pages= 68-75 | pmid=14457041 | doi=10.1055/s-0028-1096482 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14457041  }}</ref><ref name="pmid19040408" /><ref name="pmid28701598" />
*In 1962, a modified method of inserting a shunt was developed by Klinner using [[teflon]] as [[Prosthetic|prosthetic graft]] material between the [[subclavian artery]] and the [[pulmonary artery]] is used to prevent [[scarring]] of the [[subclavian artery]].<ref name="pmid144570412">{{cite journal| author=KLINNER W, PASINI M, SCHAUDIG A| title=[Anastomosis between systemic and pulmonary arteries with the aid of plastic prostheses in cyanotic heart diseases]. | journal=Thoraxchirurgie | year= 1962 | volume= 10 | issue=  | pages= 68-75 | pmid=14457041 | doi=10.1055/s-0028-1096482 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14457041  }}</ref><ref name="pmid19040408" /><ref name="pmid28701598" />


[[File:Modified-blalock-taussig-shunt-creative-commons.png|thumb|200px|none|Modified Blalock-Taussig shunt diagram. [https://radiopaedia.org/cases/74773 Source: Dr Laurent Bilodeau.]]]
[[File:Modified-blalock-taussig-shunt-creative-commons.png|thumb|200px|none|Modified Blalock-Taussig shunt diagram. [https://radiopaedia.org/cases/74773 Source: Dr Laurent Bilodeau.]]]

Revision as of 02:07, 24 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Usman Ali Akbar, M.B.B.S.[2]

Synonyms and keywords: Blalock Taussig Procedure, Procedure, Blalock-Taussig, Subclavian Pulmonary Artery Shunt, Blue Baby Operations, Modified Blalock-Taussig Procedure

Overview

The Blalock-Taussig shunt is a surgical procedure that are done as palliative procedures for cyanotic heart defects. This procedure is used to deviate blood flow to lungs from the systemic circulation to relieve cyanosis while a definitive corrective surgery can be performed at a later time. Connection between subclavian artery and pulmonary artery is usually made. There are usually two types of shunts that are used i.e classic or original Blalock-Taussig shunt and modified Blalock Taussig shunt. The classic or original BT shunt has been modified into modified Blalock-Taussig Shunt (mBTS). In this modified procedure a graft from innominate artery or subclavian artery is placed to the corresponding pulmonary artery. This type of BT shunt has superior prognostic value over classical shunt leading to a greater rate of shunt patency at 3-5 years as compared to classic or original BT Shunt.

Historical Perspective

Classic or Original Shunt

  • The classic or original BT shunt procedure was named after Alfred Blalock, surgeon, Baltimore, (1899–1964) and Helen B. Taussig, cardiologist, Baltimore/Boston, (1898–1986) who, along with Blalock's African American laboratory technician Vivien Thomas (1910–1985), developed and described the procedure.
  • Taussig noticed that the children with cyanosis along with congenital heart disease accompanied by patent ductus arteriosus have longer life time than those without PDA.
  • In 1943, Dr. Taussig approached Blalock and Thomas in their Hopkins laboratory to work on this shunt as it was hypothesized that a shunt mimicking PDA can relieve the cyanosis and improve oxygenation in congential cyanotic diseases.[1]
Original Blalock-Taussig shunt diagram. Source: Dr Laurent Bilodeau.

Modified Blalock-Taussig Shunt

Modified Blalock-Taussig shunt diagram. Source: Dr Laurent Bilodeau.

Classification

Classic/Original Blalock-Taussig Shunt

Classic/Original Blalock-Taussig Shunt
Advantages Disadvantages
The relative diameter of subclavian artery prevents excessive blood flow to lungs Thrombosis of shunt due to less diameter
Easily Reversible Risk of Dissection
Increased rate of anastomosis growth Subclavian artery is lost during the procedure

Modified Blalock Taussig Shunt

Modified Blalock Taussig Shunt
Advantages Disadvantages
It can be done on the same side of the arch Thrombosis
More patency than Classic BT shunt i.e >90 % at 2 years Pseudoaneurysm
Pulmonary artery is less distorted Chylothorax, Chylopericardium, chylous ascites

Goals of BT shunt

The ultimate endpoint goals of BT shunt is

  • To stabilize the preload hence preventing hemodilution.
  • To maintain Systemic Vascular Resistance ( afterload ) hence adequate diastolic pressure to maintain coronary perfusion
  • Increase the blood flow to the pulmonary vasculature in a supervised manner

Indications

Risk Factors

Multiple risk factors have been identified which leads to high morbidity and mortality in neonates. [5] [6]

Preparation for BT Shunt

To perform a BT shunt following pre-op preparation is done

Anesthesia induction will be based on the following patient and surgical factors

Patient Related Factors

Factors Related to Surgical Procedure

Approach

  • For right sided modified Blalock-Taussig shunt (mBTS), left lateral position is used and for left sided mBTS right lateral position is used. The approach used is usually thoracotomy.
  • For central shunts sternotomy is performed.

Complications

The immediate post-operative complications include [3]

Unilateral pulmonary edema, blalock-taussig shunt in pulmonary atresia with ventricular septal defect. Source: Dr. Charlie Chia-Tsong.

Management of Complications

Shunt failure

It is the most immediate risk during the post-operative period. It can lead to drop in oxygen saturation secondary due to shunt thrombosis or kinking. Shunt failure is a surgical emergency and should be managed as following :

  • Anticoagulation should be started. Heparin should be instituted promptly. It should be again administered if there is less risk of bleeding usually after 4 hours post-op ( when the drainage of chest shows <3ml/kg/h and aPTT is <60s. Heparin induced thrombocytopenia can occur and should be managed accordingly.
  • Patient is put on aspirin which is usually started at 3-5 mg/kg (max. dose 75mg ) OD.
  • Heparin should be continued until there is second dose of aspirin.

Blockage of BT shunt

  • Blockage or shunt thrombosis is another surgical emergency.
  • It's incidence has reported around 12%.
  • Any recent onset murmur or significant drop in oxygen saturation must be investigated.
  • Operative management is usually required and the shunt is usually repaired or replaced if necessary.

High pulmonary blood flow

Causes
  • High FiO2
  • PDA still open leading to excessive blood delivery to lungs
  • Large shunt diameter
Treatment

Following treatment is instituted:

Prognosis

  • Modified Blalock-Taussig Shunt has superior prognostic value over classic Blalock-Taussig Shunts. Following prognostic factors are compared between the two procedures in multiple studies. [7][8][9][10][11][12]
    • Rise in saturation of oxygen is greater in modified than in classic shunt
    • Shunt patency is 88.8 % in modified for 3-5 years versus 90 % in first year, 62 % in two years and 78.0 % in 3 years for classic shunt.
    • The risk of early shunt faliure is 20.8 % in modified and 51.7% in classic shunt.
    • Post-shunt increase in pulmonary arterial index (mm2/m2) is 158 +/- 21 versus 117 +/- 52 in classic Blalock-Taussig shunt.
Blalock-taussig shunt annotated image, Source: Dr. Vincent Tatco.

Alternative Shunts

Central Shunt

  • Central shunt is made by making a anastomosis between ascending aorta and main pulmonary artery.
  • A short PTFE conduit for this purpose is used.
  • It is also known as Mee's shunt. [13]
  • Internal mammary artery is used for this purpose and to create a systemic to pulmonary conduit after there has been failure of previously used BT shunt.
  • It leads to adaptation of growth and flow and reduces the risk for graft infection.
Advantages Disadvantages
Can be done in small children with small vessels Can not be performed without in patients without patent ductus arteriosus
Distortion of pulmonary vessels is avoided Entry into pericardium
Equal blood flow is provided to both lungs
Low chance of occlusion rate
Subclavian steal syndrome is usually avoided

Potts shunt

  • It can be used as an alternative to Classic BT shunt.
  • To avoid the consequences of right heart failure, it has been used as an alternative to offload the right ventricle.
  • This improves the cardiac output but the oxygen saturation is lowered and there is decreased oxygen delivery to lower extremities.
  • Pott's shunt includes a connection that is made between descending aorta and left pulmonary artery.[14]
Advantages Disadvantages
Subclavian artery is used hence large diameter so surgery can be easily performed Increased incidence of pulmonary hypertension
Lower chance of occlusion than CBTS and mBTS Increased blood flow to one lung while there is kinking of pulmonary artery
Increased risk of congestive heart failure [15]

Waterston shunt

Cooley Shunt

Advantages Disadvantages
Use of right anterolateral incision for all approaches - Mediastinal dissection is avoided Improper size of shunt can lead to right heart failure and pulmonary congestion
Total repair can be done after this shunt in future Risk of intracardiac adhesions
Complexity of the procedure

References

  1. https://www.upenn.edu/pennpress/book/1904.html
  2. KLINNER W, PASINI M, SCHAUDIG A (1962). "[Anastomosis between systemic and pulmonary arteries with the aid of plastic prostheses in cyanotic heart diseases]". Thoraxchirurgie. 10: 68–75. doi:10.1055/s-0028-1096482. PMID 14457041.
  3. 3.0 3.1 Yuan SM, Shinfeld A, Raanani E (2009). "The Blalock-Taussig shunt". J Card Surg. 24 (2): 101–8. doi:10.1111/j.1540-8191.2008.00758.x. PMID 19040408.
  4. 4.0 4.1 4.2 Kiran U, Aggarwal S, Choudhary A, Uma B, Kapoor PM (2017). "The blalock and taussig shunt revisited". Ann Card Anaesth. 20 (3): 323–330. doi:10.4103/aca.ACA_80_17. PMC 5535574. PMID 28701598.
  5. Schmoldt A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes". Biochem Pharmacol. 24 (17): 1639–41. PMID https://doi.org/10.1016/j.jamcollsurg.2012.12.027 Check |pmid= value (help).
  6. Schmoldt A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes". Biochem Pharmacol. 24 (17): 1639–41. PMID https://doi.org/10.1016/j.athoracsur.2011.02.030 Check |pmid= value (help).
  7. Al Jubair KA, Al Fagih MR, Al Jarallah AS, Al Yousef S, Ali Khan MA, Ashmeg A; et al. (1998). "Results of 546 Blalock-Taussig shunts performed in 478 patients". Cardiol Young. 8 (4): 486–90. doi:10.1017/s1047951100007150. PMID 9855103.
  8. Kim HK, Kim WH, Kim SC, Lim C, Lee CH, Kim SJ (2006). "Surgical strategy for pulmonary coarctation in the univentricular heart". Eur J Cardiothorac Surg. 29 (1): 100–4. doi:10.1016/j.ejcts.2005.10.032. PMID 16337132.
  9. Karpawich PP, Bush CP, Antillon JR, Amato JJ, Marbey ML, Agarwal KC (1985). "Modified Blalock-Taussig shunt in infants and young children. Clinical and catheterization assessment". J Thorac Cardiovasc Surg. 89 (2): 275–9. PMID 3968910.
  10. Kulkarni H, Rajani R, Dalvi B, Gupta KG, Vora A, Kelkar P (1995). "Effect of Blalock Taussig shunt on clinical parameters, left ventricular function and pulmonary arteries". J Postgrad Med. 41 (2): 34–6. PMID 10707705.
  11. Bove EL, Kohman L, Sereika S, Byrum CJ, Kavey RE, Blackman MS; et al. (1987). "The modified Blalock-Taussig shunt: analysis of adequacy and duration of palliation". Circulation. 76 (3 Pt 2): III19–23. PMID 2441893.
  12. Ullom RL, Sade RM, Crawford FA, Ross BA, Spinale F (1987). "The Blalock-Taussig shunt in infants: standard versus modified". Ann Thorac Surg. 44 (5): 539–43. doi:10.1016/s0003-4975(10)62119-4. PMID 3675059.
  13. Eghtesady, Pirooz (2015). "Potts Shunt for Children With Severe Pulmonary Hypertension". Operative Techniques in Thoracic and Cardiovascular Surgery. Elsevier BV. 20 (3): 293–305. doi:10.1053/j.optechstcvs.2016.02.003. ISSN 1522-2942.
  14. Yuan, Shi-Min; Jing, Hua (2009). "Palliative procedures for congenital heart defects". Archives of Cardiovascular Diseases. Elsevier BV. 102 (6–7): 549–557. doi:10.1016/j.acvd.2009.04.011. ISSN 1875-2136.
  15. TRUCCONE, NESTOR J.; BOWMAN, FREDERICK O.; MALM, JAMES R.; GERSONY, WELTON M. (1974). "Systemic-Pulmonary Arterial Shunts in the First Year of Life". Circulation. Ovid Technologies (Wolters Kluwer Health). 49 (3): 508–511. doi:10.1161/01.cir.49.3.508. ISSN 0009-7322.