Alzheimer's disease causes: Difference between revisions
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* Trisomy 21 | * Trisomy 21 | ||
* Over expression of amylod precursor protein | * Over expression of amylod precursor protein APP on chromosome 21 | ||
* Develop the neuropathologic hallmarks of AD after age 40 years | * Develop the neuropathologic hallmarks of AD after age 40 years | ||
| colspan="1" rowspan="1" |<1% | | colspan="1" rowspan="1" |<1% |
Revision as of 22:11, 17 September 2017
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Alzheimer's disease Microchapters |
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Alzheimer's disease causes On the Web |
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Risk calculators and risk factors for Alzheimer's disease causes |
Overview
Causes
The following are the causes of Alzheimer's dementia (AD):
Cause | Specific characteristics | Percentage of cases |
Chromosomal (Down syndrome) |
|
<1% |
All familial | ~25% | |
|
|
15%-25% |
|
|
<2% |
Unknown (includes genetic/environment interactions) |
|
~75% |