Acute retinal necrosis classification: Difference between revisions

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==Classification==
==Classification==
*Acute [[retinal]] [[necrosis]] (ARN) may be classified by staging as follows:<ref name="pmid1645179">{{cite journal |vauthors=Gartry DS, Spalton DJ, Tilzey A, Hykin PG |title=Acute retinal necrosis syndrome |journal=Br J Ophthalmol |volume=75 |issue=5 |pages=292–7 |year=1991 |pmid=1645179 |pmc=1042358 |doi= |url=}}</ref>  
*Acute [[retinal]] [[necrosis]] (ARN) may be classified by staging as follows:<ref name="pmid1645179">{{cite journal |vauthors=Gartry DS, Spalton DJ, Tilzey A, Hykin PG |title=Acute retinal necrosis syndrome |journal=Br J Ophthalmol |volume=75 |issue=5 |pages=292–7 |year=1991 |pmid=1645179 |pmc=1042358 |doi= |url=}}</ref>  
**'''Acute stage:''' Occurs at onset of disease and usually progresses past acute classification after a few weeks.
**'''Acute stage:''' Occurs at onset of disease and usually progresses past acute classification after a few weeks
***Presents with coalescence of white, necrotic tissue in the peripheral retina.
***Presents with coalescence of white, [[necrotic]] tissue in the peripheral [[retina]]
***Vaso-[[occlusion|occlusive]] retinal [[vasculitis]] is usually present.
***Vaso-[[occlusion|occlusive]] retinal [[vasculitis]] is usually present
***The [[Optic nerve|optic nerve head]] of the affected eye will appear swollen, but the [[posterior pole]] will usually not be affected during the acute stage.
***[[Optic nerve|optic nerve head]] of the affected eye will appear swollen, but the [[posterior pole]] will usually not be affected
**'''Late stage:''' Is the natural progression of the disease and will present differentiating characteristics after a few weeks up to a few months.
**'''Late stage:''' Is the natural progression of the disease and will present differentiating characteristics after a few weeks up to a few months
***Characterized by a regression of the coalesced [[necrosis]] in the peripheral [[retina]], presenting starkly contrasted [[necrotic]]/non-[[necrotic]] tissue and mild [[pigmentation]] [[scarring]] and increased [[vitreous]] debris
***Characterized by a regression of the coalesced [[necrosis]] in the peripheral [[retina]], presenting starkly contrasted [[necrotic]]/non-[[necrotic]] tissue and mild [[pigmentation]] [[scarring]] and increased [[vitreous]] debris
***[[Retinal detachment]], severe [[vision loss]], and potential [[blindness]] in the affected eye is indicative of late stage ARN.
***[[Retinal detachment]], severe [[vision loss]], and potential [[blindness]] in the affected eye
***If the infection is bilateral, the second eye will usually present signs of ARN in the weeks and months following the initial symptom manifestation in the first eye.
***If the infection is bilateral, the second eye will usually present signs of ARN in the weeks and months following the initial symptom manifestation in the first eye
*Acute [[retinal]] [[necrosis]] can also be classified by severity as follows:<ref name="pmid25356955">{{cite journal |vauthors=Brydak-Godowska J, Borkowski P, Szczepanik S, Moneta-Wielgoś J, Kęcik D |title=Clinical manifestation of self-limiting acute retinal necrosis |journal=Med. Sci. Monit. |volume=20 |issue= |pages=2088–96 |year=2014 |pmid=25356955 |pmc=4226315 |doi=10.12659/MSM.890469 |url=}}</ref>
*Acute [[retinal]] [[necrosis]] can also be classified by severity as follows:<ref name="pmid25356955">{{cite journal |vauthors=Brydak-Godowska J, Borkowski P, Szczepanik S, Moneta-Wielgoś J, Kęcik D |title=Clinical manifestation of self-limiting acute retinal necrosis |journal=Med. Sci. Monit. |volume=20 |issue= |pages=2088–96 |year=2014 |pmid=25356955 |pmc=4226315 |doi=10.12659/MSM.890469 |url=}}</ref>
**'''Mild:''' Is used to characterize ARN that is stable and non-progressive.
**'''Mild:''' Used to characterize ARN that is stable and non-progressive.
***There is usually no sign of [[retinal detachment]].
***There is usually no sign of [[retinal detachment]].
**'''Fulminant:''' ARN that is progressive and will usually lead to [[retinal detachment]] and further complications if untreated.
**'''Fulminant:''' ARN that is progressive and will usually lead to [[retinal detachment]] and further complications if left untreated


==References==
==References==

Revision as of 18:34, 9 September 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.

Overview

Acute retinal necrosis may be classified both by staging—acute or late—or by severity: mild or fulminant.

Classification

  • Acute retinal necrosis (ARN) may be classified by staging as follows:[1]
    • Acute stage: Occurs at onset of disease and usually progresses past acute classification after a few weeks
    • Late stage: Is the natural progression of the disease and will present differentiating characteristics after a few weeks up to a few months
  • Acute retinal necrosis can also be classified by severity as follows:[2]
    • Mild: Used to characterize ARN that is stable and non-progressive.
    • Fulminant: ARN that is progressive and will usually lead to retinal detachment and further complications if left untreated

References

  1. Gartry DS, Spalton DJ, Tilzey A, Hykin PG (1991). "Acute retinal necrosis syndrome". Br J Ophthalmol. 75 (5): 292–7. PMC 1042358. PMID 1645179.
  2. Brydak-Godowska J, Borkowski P, Szczepanik S, Moneta-Wielgoś J, Kęcik D (2014). "Clinical manifestation of self-limiting acute retinal necrosis". Med. Sci. Monit. 20: 2088–96. doi:10.12659/MSM.890469. PMC 4226315. PMID 25356955.

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