Appendectomy

Appendectomy
Overview
Anatomy and pathophysiology
Treatment of Appendicitis
Indications for Appendectomy
Preoperative preparation
The procedure
Recovery
Surgical outcome
Possible complications
Videos
Appendectomy on the web
Most recent articles
Most cited articles
Review articles
CME programs
powerpoint slides
Images
Ongoing trials at clinical trials.gov
US National guidelines clearinghouse
NICE guidance
FDA on Appendectomy
CDC on Appendectomy
Appendectomy in the news
Blogs on Appendectomy
Directions to Hospitals Performing Appendectomy
Risk calculators for Appendectomy

For the WikiPatient page for this topic, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-in-Chief: Mohammed A. Sbeih, M.D.[2]

An Appendicectomy in progress

Overview

An Appendicectomy (or appendectomy) is the surgical removal of the vermiform appendix. This procedure is normally performed as an emergency procedure, when the patient is suffering from acute appendicitis. In the absence of surgical facilities, intravenous antibiotics are used to delay or avoid the onset of sepsis; it is now recognised that many cases will resolve when treated non-operatively. In some cases the appendicitis resolves completely; more often, an inflammatory mass forms around the appendix. This is a relative contraindication to surgery.

Many patients do not seek medical attention early when they have symptoms, this delays the diagnosis of appendicitis,and some cases could be missed. Some surgeons accepts negative appendectomies up to 15 percent of cases, so they intervene aggressively with suspicious cases. The use of imaging studies before going through the surgery reduces the rate of negative appendictomy to less than 10 percent according to some studies.

Anatomy and pathophysiology

The appendix is a part of small intestine, it is a small, finger-like projection located in the right lower quadrant of abdomen. It is attached to the large intestine through a small opening, which allow fluids and other materials to flow in and out of the appendix, When this opening becomes blocked, there is a buildup of secretions and fluids in the appendix. It becomes swollen and may be infected (Appendicitis), also it can ruptures, resulting in peritonitis.

An Appendectomy is done for Appendicitis. The condition can be hard to be diagnosed, especially in children, older people, and women of childbearing age, since there are some medical conditions that mimics Appendicitis in their symptoms. Most often, the first symptom is vague abdominal pain around the umbilicus. The pain may be mild at first, but it becomes sharp and severe. The pain often moves into the right lower abdomen and becomes more focused in this area.

Other symptoms include:

• Diarrhea or constipation.
• Fever (usually not very high).
• Nausea and vomiting.
• Reduced appetite.

Signs of Appendicitis include:

• Guarding: Guarding occurs when a person subconsciously tenses the abdominal muscles during an examination. Voluntary guarding occurs the moment the doctor's hand touches the abdomen. Involuntary guarding occurs before the doctor actually makes contact.
• Rebound tenderness: A doctor tests for rebound tenderness by applying hand pressure to a patient's abdomen and then letting go. Pain felt upon the release of the pressure indicates rebound tenderness.
• Rovsing's sign: A doctor tests for Rovsing's sign by applying hand pressure to the lower left side of the abdomen. Pain felt on the lower right side of the abdomen upon the release of pressure on the left side indicates the presence of Rovsing's sign.
• Psoas sign: The right psoas muscle runs over the pelvis near the appendix. Flexing this muscle will cause abdominal pain if the appendix is inflamed. A doctor can check for the psoas sign by applying resistance to the right knee as the patient tries to lift the right thigh while lying down.
• Obturator sign: The right obturator muscle also runs near the appendix. A doctor tests for the obturator sign by asking the patient to lie down with the right leg bent at the knee. Moving the bent knee left and right requires flexing the obturator muscle and will cause abdominal pain if the appendix is inflamed.
• Rectal tenderness.
• Increase in white blood cells (WBC).

Treatment of Appendicitis

Most of the appendicitis cases are treated surgically and an appendectomy remains the gold standard of care. some studies showed that some patients may respond to medical therapy alone if a person is not well enough to undergo surgery or the diagnosis is unclear. Nonsurgical treatment includes antibiotics to treat infection and a liquid or soft diet until the infection subsides, but these patients are at risk for recurrent disease, that is why appendectomy is the only effective treatment for appendicitis.

There are two types of operations used to remove the appendix: the traditional open procedure and a laparoscopic procedure. Laparoscopic surgery is often used if the diagnosis is in doubt, or if it is desirable to hide the scars in the umbilicus or in the pubic hair line. Recovery may be a little quicker with laparoscopic surgery; the procedure is more expensive and resource-intensive than open surgery and generally takes a little longer, with the (low in most patients) additional risks associated with pneumoperitoneum (inflating the abdomen with gas). Advanced pelvic sepsis occasionally requires a lower midline laparotomy.

Even when the surgeon finds that the appendix is not infected during the surgery, it will be removed to prevent future problems.

Indications for Appendicectomy

Appendicitis (infected appendix) must be surgically removed (emergency appendectomy) before a hole develops in the appendix (perforation) and spreads the infection to the entire abdominal space (peritonitis).

Preoperative preparation

Before the operation, the health care provider should take a full history from the patient and examine the abdomen and rectum. Women of childbearing age may be asked to undergo a pelvic exam to rule out gynecological conditions, which sometimes cause abdominal pain similar to appendicitis. The patient's vital signs should be monitored.

Other tests should be done:

• Laboratory tests

• Blood tests are used to check for signs of infection, such as a high white blood cell count. Blood tests may also show dehydration or fluid and electrolyte imbalances. Any electrolytes disturbances should be corrected before the surgery. The patient should be adequetly hidrated with intravenous fluid, a Foley catheter may be required in severely dehydrated patients to measure the urine output.
• Urinalysis is used to rule out a urinary tract infection.
• Pregnancy test may also be ordered for women to rule out pregnancy.

• Imaging tests

If the doctors are uncertain about the diagnosis, they can perform some imaging studies to make sure the appendix is the cause of the problem, but there are no actual tests to confirm the diagnosis of appendicitis.

• Computerized tomography (CT) scans, which create cross-sectional images of the body, can help diagnose appendicitis and other sources of abdominal pain.
• Ultrasound is sometimes used to look for signs of appendicitis, especially in people who are thin or young.
• An abdominal x-ray is rarely helpful in diagnosing appendicitis but can be used to look for other sources of abdominal pain.

Women of childbearing age should have a pregnancy test before undergoing x-rays or CT scanning. Both use radiation and can be harmful to a developing fetus. Ultrasound does not use radiation and is not harmful to a fetus.

Once the diagnosis of appendicitis has been made and the surgeon decides to perform an operation, the patient should proceed to the OR (operating room) as early as possible in order to avoid the progression to perforation and peritonitis.

Before the operation, the following should be done also:

• Reviewing the anesthetic history of the patient.
• Making sure that the procedure's trocars, staplers and drains are available.
• Ordering a deep venous thrombosis (DVT) prophylaxis if applicable.
• Making sure that prophylactic antibiotics have been ordered. Prophylactic antibiotics help to prevent wound infection and abscess formation following the procedure .The patients should receive prophylactic antibiotics within one hour before the initial incision .

The selection of antibiotics is discussed separately (table 1). (See "Overview of control measures to prevent surgical site infection".)

In patients with acute non-perforated appendicitis, a single preoperative antibiotic dose for surgical wound prophylaxis is adequate. Postoperative antibiotics are unnecessary [21] In patients with perforated appendicitis, the antibiotic regimen should consist of empiric broad-spectrum therapy with activity against gram-negative rods and anaerobic organisms pending culture results [22,23] Monotherapy with a beta-lactam/beta-lactamase inhibitor, such as ampicillin-sulbactam (3 g every six hours) OR piperacillin-tazobactam (4.5 g every six hours) OR ticarcillin-clavulanate (3.1 g every six hours) A third generation cephalosporin such as ceftriaxone (1 g IV every 24 hours) PLUS metronidazole (500 mg IV every 8 to 12 hours) For patients with beta-lactam intolerance, alternative empiric regimens include:

A fluoroquinolone (eg, ciprofloxacin 400 mg IV every 12 hours or levofloxacin 500 mg or 750 IV daily) PLUS metronidazole (500 mg IV every 8 to 12 hours) Monotherapy with a carbapenem, such as imipenem-cilastatin (500 mg every six hours) OR meropenem (1 g every eight hours) OR ertapenem (1 g daily) Regardless of the initial empiric regimen, the therapeutic regimen should be revisited once culture and susceptibility results are available. Recovery of more than one organism should suggest polymicrobial infection including anaerobes, even if no anaerobes are isolated in culture. In such circumstances, anaerobic coverage should be continued. Combination therapy with a second or third generation cephalosporin or a fluoroquinolone plus metronidazole is adequate for most patients. Antibiotics should be continued until no clinical evidence of infection exists [24].

The procedure

In general terms, the procedure for an open Appendicectomy is as follows.

Antibiotics are given immediately if there are signs of sepsis, otherwise a single dose of prophylactic intravenous antibiotics is given immediately prior to surgery.

General anaesthesia is induced, with endotracheal intubation and full muscle relaxation, and the patient is positioned supine.

The abdomen is prepared and draped and is examined under anaesthesia. If a mass is present, the incision is made over the mass; otherwise, the incision is made over McBurney's point, one third of the way from the anterior superior iliac spine (ASIS) and the umbilicus; this represents the position of the base of the appendix (the position of the tip is variable).

An inflamed appendix can be life-threatening, particularly if the patient is out of reach of medical care. Historical records show a number of appendicectomies carried out by unskilled ad hoc surgeons, communicating with a base hospital by telephone or even telegraph.

If appendicitis develops in a pregnant woman, an Appendicectomy is usually performed and should not harm the fetus.

Prophylactic Appendicectomy

To find the cause of unexplained abdominal pain, exploratory surgery is sometimes performed. If the appendix is NOT the cause of symptoms, the surgeon will thoroughly check the other abdominal organs and remove the appendix anyway, to prevent it from becoming a problem in the future.

When abdominal surgery is performed for an entirely different reason (e.g. hysterectomy or bowel resection), the surgeon sometimes decides to perform an Appendicectomy in addition to the intended procedure, to eliminate the possible need of a future surgery just to remove the appendix. However, recent findings on the possible usefulness of the appendix has led to an abatement of this practice.

Recovery

Recovery time from the operation can vary from person to person. Some will take up to 3 weeks before being completely active. Others it can be a matter of days. Roy Halladay of the Toronto Blue Jays baseball team, recovered from his Appendicectomy in under 3 weeks, to return to the mound and win 3 straight games. In the case of a laparoscopic operation, the patient will have three stapled scars of about an inch in length, between the navel and pubic hair line. When a laparotomy has been performed, the patient will have a 2-4 inch scar, which will initially be heavily bruised.

Scar and Bruise 2 days after operation.

External links

• A video of the procedure
• Another video of the procedure (Either Requires Windows Media Player and will not load in Firefox 1.5; or usethis direct link with any player that can play .wmv files.)
• Appendicectomy laparoscopic : Operation Script on Wikisurgery.
• Appendicectomy laparoscopic adult: Information for patients on Wiksiurgery.
• Appendicectomy open adult: Information for patients on Wikisurgery.
• Appendicectomy open child: Information for patients on Wikisurgery.

http://www.uptodate.com/contents/acute-appendicitis-in-adults-management?source=search_result&selectedTitle=1~51

http://www.nlm.nih.gov/medlineplus/ency/article/002921.htm

http://digestive.niddk.nih.gov/ddiseases/pubs/appendicitis/

http://catalog.nucleusinc.com/displaymonograph.php?MID=215