Acute liver failure laboratory findings: Difference between revisions

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Revision as of 14:50, 16 November 2017

Acute liver failure Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:


Overview

All patients with clinical or laboratory evidence of moderate to severe acute hepatitis should have an immediate measurement of prothrombin time and careful evaluation of mental status. If the prothrombin time is prolonged by ≈ 4-6 seconds or more (INR ≥1.5) and there is any evidence of altered sensorium, the diagnosis of ALF should be strongly suspected and hospital admission is mandatory.

Laboratory Findings

LAB values in Acute liver failure Comments
  • Increased
  • Prolonged prothrombin time, resulting in an INR ≥1.5; it shows coagulopathy which is a part of acute liver failure criteria.
    • Blood glucose
  • Acetaminophen level, Toxicology screen

Initial laboratory examination must be extensive in order to evaluate both the etiology and severity.[1].


Initial laboratory analysis[1]

References

  1. 1.0 1.1 Polson J, Lee WM (2005). "AASLD position paper: the management of acute liver failure". Hepatology. 41 (5): 1179–97. doi:10.1002/hep.20703. PMID 15841455.

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