Glafenine: Difference between revisions

Glafenine
Clinical data
ATC code	N02BG03 (WHO) ;
Identifiers
	IUPAC name 2,3-Dihydroxypropyl 2-[(7-chloro-4-quinolinyl)amino]benzoate;
CAS Number	3820-67-5;
PubChem CID	3474;
ChemSpider	3355;
ChEBI	CHEBI:31653 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C19H17ClN2O4
Molar mass	372.802 g/mol
3D model (JSmol)	Interactive image;
	SMILES O=C(OCC(O)CO)c1ccccc1Nc2c3ccc(Cl)cc3ncc2;
	InChI InChI=1S/C19H17ClN2O4/c20-12-5-6-14-17(7-8-21-18(14)9-12)22-16-4-2-1-3-15(16)19(25)26-11-13(24)10-23/h1-9,13,23-24H,10-11H2,(H,21,22); Key:GWOFUCIGLDBNKM-UHFFFAOYSA-N;

VisualWikitext

Latest revision as of 19:53, 4 February 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Glafenine is a non-steroidal anti-inflammatory drug (NSAID). Use of glafenine is limited due to the risk of anaphylaxis and acute renal failure.^[1]^[2]

References

↑ "Withdrawal of glafenine". The Lancet. 339 (8789): 357. 1992. doi:10.1016/0140-6736(92)91670-4.
↑ Kleinknecht, D; Landais, P; Goldfarb, B (1986). "Analgesic and non-steroidal anti-inflammatory drug-associated acute renal failure: A prospective collaborative study". Clinical nephrology. 25 (6): 275–81. PMID 2873910.

[1] "Withdrawal of glafenine". The Lancet. 339 (8789): 357. 1992. doi:10.1016/0140-6736(92)91670-4.

[2] Kleinknecht, D; Landais, P; Goldfarb, B (1986). "Analgesic and non-steroidal anti-inflammatory drug-associated acute renal failure: A prospective collaborative study". Clinical nephrology. 25 (6): 275–81. PMID 2873910.

[1]

[2]

@@ Line 48: / Line 48: @@
 }}
 __NOTOC__
-{{CMG}}; {{AE}}
+{{CMG}}
-'''''For patient information about Glafenine, click [[Glafenine (patient information)|here]]'''''
-{{SB}}
 ==Overview==
@@ Line 60: / Line 56: @@
 ==Category==
-==FDA Package Insert==
+Non-Steroidal Anti-Inflammatory Drug
-'''  [[Glafenine indications and usage|Indications and Usage]]'''
-'''| [[Glafenine dosage and administration|Dosage and Administration]]'''
-'''| [[Glafenine dosage forms and strengths|Dosage Forms and Strengths]]'''
-'''| [[Glafenine contraindications|Contraindications]]'''
-'''| [[Glafenine warnings and precautions|Warnings and Precautions]]'''
-'''| [[Glafenine adverse reactions|Adverse Reactions]]'''
-'''| [[Glafenine drug interactions|Drug Interactions]]'''
-'''| [[Glafenine use in specific populations|Use in Specific Populations]]'''
-'''| [[Glafenine overdosage|Overdosage]]'''
-'''| [[Glafenine description|Description]]'''
-'''| [[Glafenine clinical pharmacology|Clinical Pharmacology]]'''
-'''| [[Glafenine nonclinical toxicology|Nonclinical Toxicology]]'''
-'''| [[Glafenine clinical studies|Clinical Studies]]'''
-'''| [[Glafenine how supplied storage and handling|How Supplied/Storage and Handling]]'''
-'''| [[Glafenine patient counseling information|Patient Counseling Information]]'''
-'''| [[Glafenine labels and packages|Labels and Packages]]'''
-==Mechanism of Action==
 ==References==
@@ Line 87: / Line 64: @@
 {{analgesics}}
+[[Category:Needs content]]
 [[Category:Analgesics]]
 [[Category:Quinolines]]
 [[Category:Drugs]]

v t e Analgesic products (N02A, N02B)
Opioids See also: Opioids template	Alphaprodine · Anileridine · Buprenorphine · Butorphanol · Codeine · Dextromoramide · Dextropropoxyphene · Dezocine · Desomorphine · Diamorphine · Dihydrocodeine · Dihydromorphine · Fentanyl · Hydrocodone · Hydromorphone · Ketobemidone · Levorphanol · Meptazinol · Methadone · Morphine · Nalbuphine · Nicomorphine · Opium · Oxycodone · Oxymorphone · Pethidine · Pentazocine · Pethidine · Piminodine · Piritramide · Tilidine · Tramadol · Tapentadol
Salicylic acid and derivatives	Aspirin (Acetylsalicylic Acid) · Benorylate · Diflunisal · Ethenzamide · Magnesium Salicylate · Salicin · Salicylamide · Salsalate · See also: NSAIDs
Pyrazolones	Ampyrone/Aminophenazone · Metamizole · Phenazone
Cannabinoids	Cannabis · Tetrahydrocannabinol · AM404
Anilides	Paracetamol (acetaminophen) · Phenacetin · Propacetamol
Non-Salicylate Non-Steroidal Anti-Inflammatories See also: NSAIDs template	Template:Navbox subgroup
Atypical, Adjunct & Miscellaneous	Bicifadine · Clonidine · Cyclobenzaprine · Duloxetine · Flupirtine · Gabapentin · Nefopam · Orphenadrine · Trazadone · Ziconotide

Clinical data

ATC code	N02BG03 (WHO)
Identifiers
IUPAC name 2,3-Dihydroxypropyl 2-[(7-chloro-4-quinolinyl)amino]benzoate
CAS Number	3820-67-5
PubChem CID	3474
ChemSpider	3355
ChEBI	CHEBI:31653^Y
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₉H₁₇ClN₂O₄
Molar mass	372.802 g/mol
3D model (JSmol)	Interactive image
SMILES O=C(OCC(O)CO)c1ccccc1Nc2c3ccc(Cl)cc3ncc2
InChI InChI=1S/C19H17ClN2O4/c20-12-5-6-14-17(7-8-21-18(14)9-12)22-16-4-2-1-3-15(16)19(25)26-11-13(24)10-23/h1-9,13,23-24H,10-11H2,(H,21,22) Key:GWOFUCIGLDBNKM-UHFFFAOYSA-N

Glafenine: Difference between revisions

Latest revision as of 19:53, 4 February 2014

Overview

Category

References

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