Chickenpox physical examination: Difference between revisions

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==Overview==
==Overview==
* The diagnosis of varicella is primarily clinical. In a non-immunized individual with typical [[prodrome|prodromal]] symptoms associated with the appropriate appearing rash occurring in "crops", no further investigation would normally be undertaken.
The diagnosis of [[Chickenpox|varicella]] is primarily [[clinical]]. [[Skin]] lesions on physical examination include [[Pruritic disorders|pruritic]] [[macules]] on the [[back]], [[chest]], [[face]], [[abdomen]] and [[extremities]]. [[Skin]] lesions progress to [[papules]] and [[Healing|heal]] by crusting. The other common [[skin]] lesions include [[papules]], [[vesicles]], [[pustules]] and crusts.


* If further investigation is undertaken, confirmation of the diagnosis can be sought through either examination of the fluid within the vesicles, or by testing blood for evidence of an acute immunologic reposnse. Vesicle fluid can be examined with a Tsanck smear, or better with examination for [[direct fluorescent antibody]]. The fluid can also be "cultured", whereby attempts are made to grow the virus from a fluid sample. Blood tests can be used to identify a response to acute infection (IgM) or previous infection and subsequent immunity (IgE).<ref>McPherson & Pincus: Henry's Clinical Diagnosis and Management by Laboratory Methods, 21st ed., 2007, Chapter 54.
==Physical Examination==
</ref>


* Prenatal diagnosis of foetal varicella infection can be performed using [[ultrasound]], though a delay of 5 weeks following primary maternal infection is advised. A [[polymerase chain reaction|PCR]] (DNA) test of the mother's [[amniotic fluid]] can also be performed, though the risk of [[spontaneous abortion]] due to the [[amniocentesis]] procedure is higher than the risk of the baby developing foetal varicella syndrome.
===Appearance of the Patient===
*The patient appears weak and [[tired]] with [[Rash|rashes]] spread over the [[scalp]], [[face]], [[trunk]], and [[limbs]]. The intense [[pruritis]] triggers recurrent urges to scratch.


==Physical Examination==
===Vitals===
*Low-grade [[fever]]
*[[Tachycardia]]<ref name="pmid2464648">{{cite journal| author=Schraufnagel DE, Becker RP, Balaan M, Schmid A, Claypool W| title=Silver staining of Pneumocystis carinii in the rat's lung. | journal=J Infect | year= 1989 | volume= 18 | issue= 1 | pages= 39-44 | pmid=2464648 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2464648  }} </ref>


===Appearance of the Patient===
===Skin===
[[Skin]] lesions on physical examination include:
*[[Pruritus|Pruritic]] [[macules]] on the [[back]], [[chest]], [[face]], [[abdomen]] and [[extremities]].
*[[Skin]] lesions progress to [[Papule|papules]] and [[Healing|heal]] by crusting. Other common [[skin]] lesions include:
**[[Papules]]
**[[Vesicles]]
**[[Pustules]]
**Crusts


====Chickenpox in Unvaccinated People====
===HEENT===
* The rash is generalized and [[Itch|pruritic]] (itchy). It progresses rapidly from [[macules]] to [[papules]] to [[vesicular lesions]] before crusting. The rash usually appears first on the head, chest, and back then spreads to the rest of the body. The lesions are usually most concentrated on the chest and back.
*[[Cervical lymph nodes]]
*[[Pallor]]
*[[Skin lesions]]
*[[Oral ulcers]]


* In healthy children, varicella is generally mild, with an itchy rash, malaise, and temperature up to 102°F for 2 to 3 days. Adults are at risk for more severe disease and have a higher incidence of complications. Recovery from primary varicella infection usually provides immunity for life. In otherwise healthy people, a second occurrence of varicella is uncommon and usually occurs in people who are [[immunocompromised]]. As with other viral infections, re-exposure to natural (wild-type) varicella may lead to re-infection that boosts antibody] [[titers]] without causing illness or detectable [[viremia]].
===Lungs===
Normal [[breath sounds]] are heard.


====Chickenpox in Vaccinated People====
===Abdomen===
* Chickenpox in people who are vaccinated is referred to as breakthrough varicella. Breakthrough varicella is infection with wild-type VZV occurring in a vaccinated person more than 42 days after varicella vaccination. Breakthrough varicella is usually mild. Patients typically are [[afebrile]] or have low fever and develop fewer than 50 skin lesions. They usually have a shorter illness compared to unvaccinated people who get varicella. The rash is more likely to be predominantly maculopapular rather than vesicular. However, 25%-30% of persons vaccinated with 1 dose with breakthrough varicella have clinical features typical of varicella in unvaccinated people.
The abdomen will not be [[Tenderness (medicine)|tender]] and there is no [[organomegaly]].
===Heart===
*Normal [[S1]] and [[S2]] are heard.
*[[Ventricular fibrillation]] presumed to be secondary to [[myocarditis]] has been observed in some of the adult population. <ref name="pmid2464648">{{cite journal| author=Schraufnagel DE, Becker RP, Balaan M, Schmid A, Claypool W| title=Silver staining of Pneumocystis carinii in the rat's lung. | journal=J Infect | year= 1989 | volume= 18 | issue= 1 | pages= 39-44 | pmid=2464648 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2464648  }} </ref>


* Since the clinical features of breakthrough varicella are often mild, it can be difficult to make a diagnosis on clinical presentation alone. Laboratory testing is increasingly important for confirming varicella and appropriately managing cases and their contacts. There is limited information about breakthrough varicella in persons who have received two doses of varicella vaccine, though it appears to occur less frequently among people vaccinated with two doses of varicella vaccine compared to persons who have received a single dose of varicella vaccine.
===CNS===
*The [[neurological examination]] may be normal with no focal neurological deficits.
*CNS may show the following findings:
:* Meningitis
:* Meningoencephalitis
:* Vasculopathy


==Gallery==
==Gallery==
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Latest revision as of 20:53, 29 July 2020


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]

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Overview

The diagnosis of varicella is primarily clinical. Skin lesions on physical examination include pruritic macules on the back, chest, face, abdomen and extremities. Skin lesions progress to papules and heal by crusting. The other common skin lesions include papules, vesicles, pustules and crusts.

Physical Examination

Appearance of the Patient

Vitals

Skin

Skin lesions on physical examination include:

HEENT

Lungs

Normal breath sounds are heard.

Abdomen

The abdomen will not be tender and there is no organomegaly.

Heart

CNS

  • Meningitis
  • Meningoencephalitis
  • Vasculopathy

Gallery

Unvaccinated Individuals

Vaccinated Individuals

References

  1. 1.0 1.1 Schraufnagel DE, Becker RP, Balaan M, Schmid A, Claypool W (1989). "Silver staining of Pneumocystis carinii in the rat's lung". J Infect. 18 (1): 39–44. PMID 2464648.
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 2.18 2.19 2.20 2.21 2.22 2.23 2.24 2.25 2.26 2.27 2.28 2.29 2.30 2.31 2.32 2.33 2.34 2.35 2.36 2.37 "Public Health Image Library (PHIL)".


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