Undecylenic acid
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| Undecylenic acid | |
|---|---|
| |
| IUPAC name | undec-10-enoic acid |
| Identifiers | |
| CAS number | |
| PubChem | |
| MeSH | |
| SMILES | C=CCCCCCCCCC(=O)O |
| Properties | |
| Molecular formula | C11H20O2 |
| Molar mass | 184.275 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references | |
Undecylenic / Undecenoic Acid is an organic unsaturated fatty acid derived from natural castor oil. It is the common name of the 10-undecenoic acid (CH2CH(CH2)8COOH). It is used in the manufacture of pharmaceuticals, cosmetics and perfumery including anti-dandruff shampoos, anti-microbial powders and as a musk in perfumes and aromas.[1]Undecylenic acid is produced by cracking of Castor oil under pressure.[1]
Medicinal uses
Undecylenic acid is a natural fungicide and is FDA approved in over-the-counter medications for skin disorders or problems. It is the active ingredient in medications for skin infections, and relieves itching, burning, and irritation. For example, it is used against fungal skin infections such as athlete's foot, ringworm, Candida albicans. [1] It is also used in the treatment of psoriasis.[1]
Undecylenic acid is also proven to have anti-bacterial and anti-viral properties that are effective on viral skin infections such as the herpes simplex virus. [1]
Products That Contain Undecylenic Acid
Given in alphabetical order. Percentage content of Undecylenic Acid given in parenthesis. Concentrations greater than 10% are meant for application to nails and may be too strong for skin application (i.e. dilution may be necessary).
- DermaZinc Cream (% not listed)
- Elon Dual Defense Anti-Fungal (25%)
- FungiCure Anti-fungal Liquid, extra strength (10%)
- Fungi Nail Anti-fungal Solution (25%)
- Fungus-No-More (25%)
- Tineacide Antifungal Cream (10%)
References
Antifungals (D01 and J02) | |
|---|---|
| Antibiotics | Griseofulvin • polyene antimycotics (Natamycin, Nystatin) |
| Topical azoles | imidazoles (Bifonazole, Clomidazole, Clotrimazole, Econazole, Fenticonazole, Ketoconazole, Isoconazole, Miconazole, Oxiconazole, Sertaconazole, Sulconazole, Tioconazole) • triazoles (Fluconazole) • benzimidazole (Thiabendazole) |
| Other topicals | Ciclopirox • Ethylparaben • Flucytosine • Salicylic acid • Selenium sulfide • Tolnaftate • Undecylenic acid • allylamines (Amorolfine, Butenafine, Naftifine, Terbinafine) |
| For systemic use | Griseofulvin • allylamine (Terbinafine) • polyene antimycotic (Amphotericin B) • triazoles (Itraconazole, Posaconazole, Voriconazole) • echinocandins (Anidulafungin, Caspofungin, Micafungin) |
| Other | Tea tree oil • citronella oil • lemon grass • orange oil • patchouli • lemon myrtle |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
