Uridine diphosphate glucose

Uridine diphosphate glucose
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Identifiers
CAS number	133-89-1
PubChem	8629
MeSH	Uridine+Diphosphate+Glucose
SMILES	C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O) OP(=O)(O)OC3C(C(C(C(O3)CO)O)O)O)O)O
Properties
Molecular formula	C15H24N2O17P2
Molar mass	566.302 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Uridine diphosphate glucose (uracil-diphosphate glucose, UDP-glucose) is a nucleotide sugar. It is involved in glycosyltransferase reactions in metabolism.

Functions

It is used in nucleotide sugars metabolism as an activated form of glucose as a substrate for enzymes called glucosyltransferases.

It is a precursor of glycogen and can be converted into UDP-galactose and UDP-glucuronic acid, which can then be used as substrates by the enzymes that make polysaccharides containing galactose and glucuronic acid.

UDP-glucose can also be used as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.

Components

UDP-glucose consists of the pyrophosphate group, the pentose sugar ribose, glucose, and the nucleobase uracil.

See also

• Nucleoside
• Nucleotide
• DNA
• RNA
• Oligonucleotide
• Uracil
• Uridine diphosphate

<tr bgcolor="#ccccff"><td colspan="3" align="center">Major families of biochemicals</td></tr><tr><td colspan="3" style="text-align: center;">Peptides | Amino acids | Nucleic acids | Carbohydrates | Nucleotide sugars | Lipids | Terpenes | Carotenoids | Tetrapyrroles | Enzyme cofactors | Steroids | Flavonoids | Alkaloids | Polyketides | Glycosides</td></tr><tr bgcolor="pink"><td style="white-space: nowrap; width: 10%; color: pink;">Analogues of nucleic acids:</td><td align="center">Types of nucleotide sugars</td><td style="white-space: nowrap; width: 10%; color: pink;">Analogues of nucleic acids:</td></tr>