Thin basement membrane disease epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Marufa Marium, M.B.B.S[2]
Overview
The incidence of thin basement membrane disease is 1%-2% based on data available in 2006. The prevalence of thin basement membrane disease is 1%.Thin basement membrane disease affects children and adult equally with more predominance in female. According to available data most cases are reported in developed countries specially in Europe where majority of patient are of Caucasians race. Chinese, Indians, Africans are less commonly affected.
Epidemiology andDemographics
Incidence
- In 2006, the incidence of TBMD was estimated to be 1%-2% cases per 3471 TBMD cases on renal biopsy.[1]
Prevalence
- The prevalence of TBMD is approximately 1%.[2]
Case fatality rate/Mortality rate
- There is no sufficient data available on case fatality rate or mortality rate.
Age
- Patients of all age groups may develop Thin basement membrane disease. The median age of children is 7 years whereas in adult it is 37 years of age.[3]
Race
- Thin basement membrane disease usually affects individuals of the Caucasians according to available data. Chinese, Indians and African individuals are less likely to develop TBMD.
Gender
- Thin basement membrane diseaseaffects all ages of men and women equally.
- Some studies presented data showing women are more affected with TBMD than male.[4]
Region
- The majority of thin basement membrane disease cases are reported in Europe.
Developed Countries
- The majority of TBMD cases are reported in Developed countries.
Developing Countries
- There are no distinctive data showing the association of thin basement membrane disease with developing countries.
References
- ↑ Haas M (May 2006). "Thin glomerular basement membrane nephropathy: incidence in 3471 consecutive renal biopsies examined by electron microscopy". Arch Pathol Lab Med. 130 (5): 699–706. doi:10.1043/1543-2165(2006)130[699:TGBMNI]2.0.CO;2. PMID 16683888.
- ↑ Wang YY, Savige J (May 2005). "The epidemiology of thin basement membrane nephropathy". Semin Nephrol. 25 (3): 136–9. doi:10.1016/j.semnephrol.2005.01.003. PMID 15880322.
- ↑ "Thin basement membrane nephropathy - Kidney International".
- ↑ Tryggvason K, Patrakka J (March 2006). "Thin basement membrane nephropathy". J Am Soc Nephrol. 17 (3): 813–22. doi:10.1681/ASN.2005070737. PMID 16467446.