Tetrazepam
You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.
| Image:Tetrazepam.svg | |
| Image:Tetrazepam3d.png | |
| Tetrazepam
| |
| Systematic (IUPAC) name | |
| 7-Chloro-5-(cyclohex-1-enyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one | |
| Identifiers | |
| CAS number | |
| ATC code | M03 |
| PubChem | |
| Chemical data | |
| Formula | C16H17ClN2O |
| Mol. mass | 288.772 |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | 15 hours |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | Oral |
Tetrazepam, (Clinoxan, Epsipam, Myolastan, Musaril, Relaxam, Spasmorelax) is a benzodiazepine derivative with anxiolytic and muscle relaxant properties. It is used mainly in Austria, France, Belgium and Germany to treat muscle spasm, anxiety disorders such as panic attacks, or more rarely to treat depression, premenstrual syndrome or agoraphobia. Tetrazepam has relatively little sedative effect at low doses while still producing useful muscle relaxation and anxiety relief.
The indicated adult dose for muscle spasm is 50 mg three to four times per day, increased if necessary to a maximum of 800mg per day, in divided doses. Tetrazepam is not generally recommended for use in children, except on the advice of a specialist.
Tetrazepam is only available in one strength and formulation, 50mg tablets. This dose is approximately equivalent to 5-7.5mg oral diazepam. Prolonged use, as with all benzodiazepines, should be avoided, as tolerance occurs and there is a risk of possible dependence and a benzodiazepine withdrawal syndrome after stopping or reducing dosage.
Skeletal Muscle relaxants (M03) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Peripherally acting (primarily antinicotinic, neuromuscular-blocking drugs) |
| ||||||||
| Centrally Acting |
| ||||||||
| Directly acting | Dantrolene | ||||||||
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
