Statin therapy to support PCI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Percutaneous coronary intervention Microchapters

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Patient Information

Overview

Risk Stratification and Benefits of PCI

Preparation of the Patient for PCI

Equipment Used During PCI

Pharmacotherapy to Support PCI

Vascular Closure Devices

Recommendations for Perioperative Management–Timing of Elective Noncardiac Surgery in Patients Treated With PCI and DAPT

Post-PCI Management

Risk Reduction After PCI

Post-PCI follow up

Hybrid coronary revascularization

PCI approaches

PCI Complications

Factors Associated with Complications
Vessel Perforation
Dissection
Distal Embolization
No-reflow
Coronary Vasospasm
Abrupt Closure
Access Site Complications
Peri-procedure Bleeding
Restenosis
Renal Failure
Thrombocytopenia
Late Acquired Stent Malapposition
Loss of Side Branch
Multiple Complications

PCI in Specific Patients

Cardiogenic Shock
Left Main Coronary Artery Disease
Refractory Ventricular Arrhythmia
Severely Depressed Ventricular Function
Sole Remaining Conduit
Unprotected Left Main Patient
Adjuncts for High Risk PCI

PCI in Specific Lesion Types

Classification of the Lesion
The Calcified Lesion
The Ostial Lesion
The Angulated or Tortuous Lesion
The Bifurcation Lesion
The Long Lesion
The Bridge Lesion
Vasospasm
The Chronic Total Occlusion
The Left Internal Mammary Artery
Multivessel Disease
Distal Anastomotic Lesions
Left Main Intervention
The Thrombotic Lesion

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Statin Therapy to Support PCI

2011 ACCF/AHA/SCAI Guidelines for Percutaneous Coronary Intervention (DO NOT EDIT)[1]

Statin Treatment (DO NOT EDIT)[1]

Class IIa

"1. Administration of a high-dose statin is reasonable before PCI to reduce the risk of peri-procedural myocardial infarction. (Level of Evidence: A for statin-naïve patients) [2][3][4][5][6][7][8]; (Level of Evidence: B for those on chronic statin therapy) [9]"

References

  1. 1.0 1.1 Levine GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B, Chambers CE, Ellis SG, Guyton RA, Hollenberg SM, Khot UN, Lange RA, Mauri L, Mehran R, Moussa ID, Mukherjee D, Nallamothu BK, Ting HH (2011). "2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention: Executive Summary A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and Interventions" (PDF). Journal of the American College of Cardiology. 58 (24): 2550–83. doi:10.1016/j.jacc.2011.08.006. PMID 22070837. Retrieved 2011-12-08. Text "PDF" ignored (help); Unknown parameter |month= ignored (help)
  2. Briguori C, Colombo A, Airoldi F, Violante A, Focaccio A, Balestrieri P, Paolo Elia P, Golia B, Lepore S, Riviezzo G, Scarpato P, Librera M, Bonizzoni E, Ricciardelli B (2004). "Statin administration before percutaneous coronary intervention: impact on periprocedural myocardial infarction". European Heart Journal. 25 (20): 1822–8. doi:10.1016/j.ehj.2004.07.017. PMID 15474697. Retrieved 2011-12-06. Unknown parameter |month= ignored (help)
  3. Briguori C, Visconti G, Focaccio A, Golia B, Chieffo A, Castelli A, Mussardo M, Montorfano M, Ricciardelli B, Colombo A (2009). "Novel approaches for preventing or limiting events (Naples) II trial: impact of a single high loading dose of atorvastatin on periprocedural myocardial infarction". Journal of the American College of Cardiology. 54 (23): 2157–63. doi:10.1016/j.jacc.2009.07.005. PMID 19664895. Retrieved 2011-12-06. Unknown parameter |month= ignored (help)
  4. Pasceri V, Patti G, Nusca A, Pristipino C, Richichi G, Di Sciascio G (2004). "Randomized trial of atorvastatin for reduction of myocardial damage during coronary intervention: results from the ARMYDA (Atorvastatin for Reduction of MYocardial Damage during Angioplasty) study". Circulation. 110 (6): 674–8. doi:10.1161/01.CIR.0000137828.06205.87. PMID 15277322. Retrieved 2011-12-06. Unknown parameter |month= ignored (help)
  5. Patti G, Pasceri V, Colonna G, Miglionico M, Fischetti D, Sardella G, Montinaro A, Di Sciascio G (2007). "Atorvastatin pretreatment improves outcomes in patients with acute coronary syndromes undergoing early percutaneous coronary intervention: results of the ARMYDA-ACS randomized trial". Journal of the American College of Cardiology. 49 (12): 1272–8. doi:10.1016/j.jacc.2007.02.025. PMID 17394957. Retrieved 2011-12-06. Unknown parameter |month= ignored (help)
  6. Yun KH, Jeong MH, Oh SK, Rhee SJ, Park EM, Lee EM, Yoo NJ, Kim NH, Ahn YK, Jeong JW (2009). "The beneficial effect of high loading dose of rosuvastatin before percutaneous coronary intervention in patients with acute coronary syndrome". International Journal of Cardiology. 137 (3): 246–51. doi:10.1016/j.ijcard.2008.06.055. PMID 18706705. Retrieved 2011-12-06. Unknown parameter |month= ignored (help)
  7. Zhang F, Dong L, Ge J (2010). "Effect of statins pretreatment on periprocedural myocardial infarction in patients undergoing percutaneous coronary intervention: a meta-analysis". Annals of Medicine. 42 (3): 171–7. doi:10.3109/07853890903463976. PMID 20384433. Retrieved 2011-12-06. Unknown parameter |month= ignored (help)
  8. Winchester DE, Wen X, Xie L, Bavry AA (2010). "Evidence of pre-procedural statin therapy a meta-analysis of randomized trials". Journal of the American College of Cardiology. 56 (14): 1099–109. doi:10.1016/j.jacc.2010.04.023. PMID 20825761. Retrieved 2011-12-06. Unknown parameter |month= ignored (help)
  9. Di Sciascio G, Patti G, Pasceri V, Gaspardone A, Colonna G, Montinaro A (2009). "Efficacy of atorvastatin reload in patients on chronic statin therapy undergoing percutaneous coronary intervention: results of the ARMYDA-RECAPTURE (Atorvastatin for Reduction of Myocardial Damage During Angioplasty) Randomized Trial". Journal of the American College of Cardiology. 54 (6): 558–65. doi:10.1016/j.jacc.2009.05.028. PMID 19643320. Retrieved 2011-12-06. Unknown parameter |month= ignored (help)

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