Staphylococcal scalded skin syndrome
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| Staphylococcal scalded skin syndrome Classification and external resources | |
| ICD-10 | L00. |
|---|---|
| ICD-9 | 695.81 |
| DiseasesDB | 29437 |
| eMedicine | derm/402 emerg/782 |
| MeSH | D013206 |
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Staphylococcal scalded skin syndrome, SSSS, also known as Pemphigus neonatorum or Ritter's disease, is a dermatological condition caused by Staphylococcus aureus.
Pathophysiology
The syndrome is induced by 2 epidermolytic exotoxins A and B, which are released by S. aureus and cause the epidermis to detach from the underlying dermis. One of the exotoxins is produced by the bacterial chromosome, while the other is produced by a plasmid. (Bacterial plasmids are pieces of self-replicating DNA that often code for secondary characteristics, such as antibiotic resistance, and toxin production.)
Symptoms
The disease presents with the widespread formation of fluid filled blisters that are thin walled and easily ruptured. Ritter's Disease of the Newborn is the most severe form of SSSS with similar signs and symptoms.
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
