Actinobacteria
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Ongoing Trials on Actinobacteria at Clinical Trials.gov Trial results on Actinobacteria Clinical Trials on Actinobacteria at Google
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US National Guidelines Clearinghouse on Actinobacteria NICE Guidance on Actinobacteria
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Patient resources on Actinobacteria Discussion groups on Actinobacteria Patient Handouts on Actinobacteria Directions to Hospitals Treating Actinobacteria Risk calculators and risk factors for Actinobacteria
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Causes & Risk Factors for Actinobacteria | |
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The Actinobacteria or Actinomycetes are a group of Gram-positive bacteria with high G+C ratio. They include some of the most common soil life, playing an important role in decomposition of organic materials, such as cellulose and chitin and thereby play a vital part in organic matter turnover and carbon cycle. Thus replenishing the supply of nutrients in the soil and is an important part of humus formation.
Actinobacteria are well known as secondary metabolite producers and hence of high pharmacological and commercial interest. In 1940 Selman Waksman discovered that the soil bacteria he was studying made actinomycin, a discovery which granted him a Nobel Prize. Since then hundreds of naturally occurring antibiotics have been discovered in these terrestrial microorganisms, especially from the genus Streptomyces.
Other Actinobacteria inhabit plants and animals, including a few pathogens, such as Mycobacterium, Corynebacterium, Nocardia, Rhodococcus and a few species of Streptomyces.
Genomes of 44 different strains of Actinobacteria from different genera are either already sequenced or underway right now.
Some Actinobacteria form branching filaments, which somewhat resemble the mycelia of the unrelated fungi, among which they were originally classified under the older name Actinomycetes. Most members are aerobic, but a few, such as Actinomyces israelii, can grow under anaerobic conditions. Unlike the Firmicutes, the other main group of Gram-positive bacteria, they have DNA with a high GC-content and some Actinomycetes species produce external spores.
Representative genera include:
- Actinomyces
- Arthrobacter
- Corynebacterium
- Frankia
- Micrococcus
- Micromonospora
- Mycobacterium
- Nocardia
- Propionibacterium
- Streptomyces
References
- Stackebrandt E, Rainey FA, and Ward-Rainey NL (1997). Proposal for a new hierarchic classification system, Domingus classis nov. Int J Syst Bacteriol 47:479-491. Abstract
External links
WikiDoc Research Resources for Actinobacteria | |
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| Articles on Actinobacteria | Most recent articles on Actinobacteria • Most cited articles on Actinobacteria • Review articles on Actinobacteria • Articles on Actinobacteria in N Eng J Med, Lancet, BMJ |
| Media (Slides, Video, Images, MP3) on Actinobacteria | Powerpoint slides on Actinobacteria • Images of Actinobacteria • Photos of Actinobacteria • Podcasts & MP3s on Actinobacteria • Videos on Actinobacteria |
| Evidence Based Medicine Regarding Actinobacteria | Cochrane Collaboration on Actinobacteria • Bandolier on Actinobacteria • TRIP on Actinobacteria |
| Cost Effectiveness of Actinobacteria | Cost Effectiveness of Actinobacteria |
| Clinical Trials Involving Actinobacteria | Ongoing Trials on Actinobacteria at Clinical Trials.gov • Trial results on Actinobacteria • Clinical Trials on Actinobacteria at Google |
| Guidelines / Policies / Government Resources (FDA/CDC) Regarding Actinobacteria | US National Guidelines Clearinghouse on Actinobacteria • NICE Guidance on Actinobacteria • NHS PRODIGY Guidance • FDA on Actinobacteria • CDC on Actinobacteria |
| Textbook Information on Actinobacteria | Books and Textbook Information on Actinobacteria |
| Pharmacology Resources on Actinobacteria | Dosing of Actinobacteria • Drug interactions with Actinobacteria • Side effects of Actinobacteria • Allergic reactions to Actinobacteria • Overdose information on Actinobacteria • Carcinogenicity information on Actinobacteria • Actinobacteria in pregnancy • Pharmacokinetics of Actinobacteria • |
| Genetics, Pharmacogenomics, and Proteinomics of Actinobacteria | Genetics of Actinobacteria • Pharmacogenomics of Actinobacteria • Proteomics of Actinobacteria |
| Newstories on Actinobacteria | Actinobacteria in the news • Be alerted to news on Actinobacteria • News trends on Actinobacteria |
| Commentary on Actinobacteria | Blogs on Actinobacteria |
| Patient Resources on Actinobacteria | Patient resources on Actinobacteria • Discussion groups on Actinobacteria • Patient Handouts on Actinobacteria • Directions to Hospitals Treating Actinobacteria • Risk calculators and risk factors for Actinobacteria |
| Healthcare Provider Resources on Actinobacteria | Symptoms of Actinobacteria • Causes & Risk Factors for Actinobacteria • Diagnostic studies for Actinobacteria • Treatment of Actinobacteria |
| Continuing Medical Education (CME) Programs on Actinobacteria | CME Programs on Actinobacteria |
| International Resources on Actinobacteria | Actinobacteria en Espanol • Actinobacteria en Francais |
| Business Resources on Actinobacteria | Actinobacteria in the Marketplace • Patents on Actinobacteria |
| Informatics Resources on Actinobacteria | List of terms related to Actinobacteria |
de:Actinobacteriaga:Actinomycetes it:Actinobacteria nl:Straalzwammenno:Actinobacteria nn:Actinomycesuk:Актинобактерії
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
