Small cell carcinoma of the lung staging
Small Cell Carcinoma of the Lung Microchapters
Small cell carcinoma of the lung staging On the Web
American Roentgen Ray Society Images of Small cell carcinoma of the lung staging
Staging schemes for small cell lung cancer (SCLC) have been developed by the Veterans Administration Lung Study Group (VALG), the American Joint Committee on Cancer (AJCC), and the National Comprehensive Cancer Network (NCCN). The Veterans Administration Lung Study Group (VALG) staging scheme is the oldest among the three staging schemes. Although the AJCC staging scheme is newer than that of the VALG, clinicians commonly use the VALG staging system because it has been referred to in most clinical trials. The NCNN combines the AJCC (TNM) staging scheme with the VALG staging scheme.
The Veterans Administration Lung Study Group (VALG) staging, also known as VA staging, is an old staging system that has been previously used in most clinical trials. Shown below is a table depicting the VA staging system which classifies SCLC into two stages.
|Limited SCLC||Limited SCLC is characterized by the strict involvement of the ipsilateral lung.|
|Extensive SCLC||Extensive SCLC extends beyond the ipsilateral lung and may involve the contralateral lung, or can be associated with pleural effusion, pericardial effusion, or hematogenous spread.|
AJCC and TNM Staging
Shown below is a table summarizing the staging of lung cancer according to the American Joint Committee on Cancer (AJCC). This staging scheme is the same for both SCLC and non small cell lung cancer.
For more information about the TNM staging, click here.
|Stage IIIA||T1, T2||N2||M0|
|Stage IIIB||Any T||N3||M0|
|Stage IV||Any T||Any N||M1|
The National Comprehensive Cancer Network (NCCN) staging system combines the staging scheme of the AJCC and that of the VALG. Although the AJCC staging scheme is newer than that of the VALG, clinicians commonly use the VALG staging system because it has been commonly referred to in clinical trials. Shown below is a table depicting the NCNN staging which classifies SCLC into two stages.
|Limited SCLC||Limited SCLC includes lung cancer cases of stage I, II, or III which can be treated with radiation therapy.|
This stage does not include tumor T3 or T4 with multiple lung nodules, as well as tumor or lymph nodes that are too large to fit in the radiation plan.
|Extensive SCLC||Extensive SCLC includes all SCLC categorized as stage IV, or |
- Micke P, Faldum A, Metz T, Beeh KM, Bittinger F, Hengstler JG; et al. (2002). "Staging small cell lung cancer: Veterans Administration Lung Study Group versus International Association for the Study of Lung Cancer--what limits limited disease?". Lung Cancer. 37 (3): 271–6. PMID 12234695.
- Shepherd FA, Crowley J, Van Houtte P, Postmus PE, Carney D, Chansky K; et al. (2007). "The International Association for the Study of Lung Cancer lung cancer staging project: proposals regarding the clinical staging of small cell lung cancer in the forthcoming (seventh) edition of the tumor, node, metastasis classification for lung cancer". J Thorac Oncol. 2 (12): 1067–77. doi:10.1097/JTO.0b013e31815bdc0d. PMID 18090577.
- NCCN Clinical Practice Guidelines in Oncology. Small Cell Lung Cancer, version 2.2014