Septic arthritis other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Venkata Sivakrishna Kumar Pulivarthi M.B.B.S [2]

Overview

Polymerase chain reaction (PCR) of synovial fluid is the test useful in the management of septic arthritis which allows more rapid or accurate diagnosis.[1]

Other Diagnostic Studies

Polymerase chain reaction of synovial fluid is useful to differentiate the causes of septic arthritis such as Borrelia sps. It is not useful to diagnose microorganism such as Staphylococcus or Streptococcal sps, but it is useful to differentiate rare causes where culture is negative or less sensitive.[2]

References

  1. Ilharreborde B, Bidet P, Lorrot M, Even J, Mariani-Kurkdjian P, Liguori S et al. (2009) New real-time PCR-based method for Kingella kingae DNA detection: application to samples collected from 89 children with acute arthritis. J Clin Microbiol 47 (6):1837-41. DOI:10.1128/JCM.00144-09 PMID: 19369442
  2. Mathews CJ, Kingsley G, Field M, Jones A, Weston VC, Phillips M et al. (2008) Management of septic arthritis: a systematic review. Postgrad Med J 84 (991):265-70. DOI:10.1136/ard.2006.058909 PMID: 18508984

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