Preoptic area
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| Brain: Preoptic area | ||
|---|---|---|
| Preoptic area is 'PO', at left, in blue. | ||
| NeuroNames | hier-360 | |
| MeSH | Preoptic+area | |
| Dorlands/Elsevier | n_11/12582622 | |
The preoptic area is a region of the hypothalamus. According to the MeSH classification, it is considered part of the anterior hypothalamus.
Contents |
Functions
The preoptic area is responsible for thermoregulation and receives nervous stimulation from thermoreceptors in the skin, mucous membranes and hypothalamus itself.
This area propagates stimuli to either the heat-losing or heat-promoting centres of the hypothalamus.
Nuclei
There are four nuclei in this region, according to Terminologia Anatomica:
- nucleus preopticus lateralis (lateral preoptic nucleus)
- nucleus preopticus medialis (medial preoptic nucleus) - also releases gonadotropin-releasing hormone
- nucleus preopticus medianus (median preoptic nucleus)
- nucleus preopticus periventricularis (periventricular preoptic nucleus)
Aging
Studies in female mice have shown that estrogen receptor-alpha declines in the pre-optic hypothalamus as they grow old. The female mice that were given a calorically restricted diet during the majority of their lives, maintained higher levels of ERα in the pre-optic hypothalamus than their non-calorically restricted counterparts. [1]
References
- ↑ Yaghmaie F, Saeed O, Garan SA, Freitag W, Timiras PS, Sternberg H. (2005). "Caloric restriction reduces cell loss and maintains estrogen receptor-alpha immunoreactivity in the pre-optic hypothalamus of female B6D2F1 mice.". Neuro Endocrinol Lett. 26 (3): 197-203. PMID 15990721.
See also
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
