Pilocytic astrocytoma
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Overview
Pilocytic astrocytoma is a brain tumor that occurs predominantly in children and involves the midline, basal and posterior fossa structures. It is generally considered a benign tumor of childhood. It is often cystic and if solid, it tends to be well circumscribed. It is characteristically a contrast enhancing tumour by current imaging investigations (e.g. CT scan, MRI)
Microscopically, the tumor is composed of bipolar cells with long "hairlike" GFAP-positive processes. Rosenthal fibers, eosinophilic granular bodies and microcysts are often present.
It is classified as Grade 1 Astrocytoma.
External links
- Medical Image Database
- UC
- fightJPA - An Organization Dedicated to Funding Research into Juvenile Pilocytic Astrocytoma
Acknowledgements
The content on this page was first contributed by: C. Michael Gibson, M.S., M.D.
Initial content for this page in some instances came from Wikipedia
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
