Astrocytoma historical perspective

Jump to: navigation, search

Astrocytoma Microchapters


Patient Information


Historical Perspective




Differentiating Astrocytoma from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis


History and Symptoms

Physical Examination

Laboratory Findings





Medical Therapy


Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Study

Case #1

Astrocytoma historical perspective On the Web

Most recent articles

cited articles

Review articles

CME Programs

Powerpoint slides


American Roentgen Ray Society Images of Astrocytoma historical perspective

All Images
Echo & Ultrasound
CT Images

Ongoing Trials at Clinical

US National Guidelines Clearinghouse

NICE Guidance

FDA on Astrocytoma historical perspective

CDC on Astrocytoma historical perspective

Astrocytoma historical perspective in the news

Blogs on Astrocytoma historical perspective

Directions to Hospitals Treating Astrocytoma

Risk calculators and risk factors for Astrocytoma historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]


Astrocytoma was first described by Virchow in 1840 as glioma duram. In 1932, the histological description of cerebellar astrocytoma was given by Bergstrand.

Historical Perspective

  • Astrocytoma was the first glioma tumor to be described.
  • Astrocytoma was first explained as glioma duram by Virchow in 1840.
  • Astrocytoma was decribed as spider cell glioma by T.Simon in 1874.
  • Astrocytoma was also described as astroma by M von Lenhossek in 1895.
  • Earlier nomenclatures included:
  • Amoebiod giant cell glioma in 1918 by O Lotmar
  • Fibrillary, protoplasmic astrocytoma and astroblastoma in 1926 by Baley and Cushing
  • Afibrillary and gigantocellular astrocytoma in 1932 by Roussy and Oberling
  • Piloid, gemistocytic and diffuse astrocytoma in 1932 by Penfield [1]
  • Cerebellar astrocytoma was first described by Harvey Cushing in 1931.[2]
  • Histological description of astrocytoma was first given by Bergstrand in 1932.[3]

Notable cases

  • In March 1990, prolific United States Republican Party political strategist Lee Atwater was diagnosed with astrocytoma after a tumor was found in his right parietal lobe. After undergoing radiation therapy (including the then-new implant radiation treatment), Atwater died the following year at the age of 40.[4]
  • 2001 World Rally Championship winner Richard Burns was diagnosed with it after suffering a blackout while traveling to the 2003 Wales Rally GB. He died on 25 November 2005, four years to the day after winning the World Rally Championship Championship.
  • University of Texas sniper Charles Whitman who killed multiple people during a mass murder event in 1966 was diagnosed with astrocytoma post-mortem. The Connally Commission investigating the shooting concluded the tumor "conceivably could have contributed to his inability to control his emotions and actions."[6]
  • Mo Mowlam (Secretary of State for Northern Ireland May 1997 - October 1999) - had a mild form of glioma on left frontal lobe.[7]
  • Dan Quisenberry (Major League pitcher) was diagnosed with grade IV astrocytoma in January 1998. He died in 1998 in Leawood, Kansas.[8]
  • Robert Moog (American pioneer of electronic music) was diagnosed with grade IV astrocytoma on April 28, 2005. He died on August 21, 2005 in Asheville, North Carolina.


  1. lch, Klaus (1986). Brain Tumors Their Biology and Pathology. Berlin, Heidelberg: Springer Berlin Heidelberg. ISBN 978-3-642-68180-6. 
  2. Collins VP, Jones DT, Giannini C (2015). "Pilocytic astrocytoma: pathology, molecular mechanisms and markers.". Acta Neuropathol. 129 (6): 775–88. PMC 4436848Freely accessible. PMID 25792358. doi:10.1007/s00401-015-1410-7. 
  3. lch, Klaus (1986). Brain Tumors Their Biology and Pathology. Berlin, Heidelberg: Springer Berlin Heidelberg. ISBN 978-3-642-68178-3. 
  4. Brady, John (December 1, 1996). "I'm Still Lee Atwater", The Washington Post, retrieved 2010-04-11.
  5. "Kennedy fought aggressive cancer". CNN. August 26, 2009. Retrieved 2010-02-27. 
  6. Waring, Thomas R., ed. "Jury Blames Tumor For Killings: Doctor Says Whitman Unaffected"" The News and Courier [Charleston] 05 Aug. 1966: 9B. Print.
  7. Langdon, Julia (17 January 2010). "Mo Mowlam told PM brain tumour was benign to get job as Cabinet minister". Daily Mail. London. 
  8. Henderson, Heather (1999). "Dan Quisenberry - In His Own Words" The 1999 Big Bad Baseball Annual. Retrieved June 24, 2013.