Phorate

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Phorate

File:Phorate.svg
Names
IUPAC name O,O-Diethyl S-[(ethylsulfanyl)methyl] phosphorodithioate
Other names Thimet
Identifiers
CAS Number	298-02-2 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:38764 N
ChEMBL	ChEMBL510014 N
ChemSpider	4626 Y
ECHA InfoCard
PubChem CID	4790
InChI InChI=1S/C7H17O2PS3/c1-4-8-10(11,9-5-2)13-7-12-6-3/h4-7H2,1-3H3 Y Key: BULVZWIRKLYCBC-UHFFFAOYSA-N Y InChI=1/C7H17O2PS3/c1-4-8-10(11,9-5-2)13-7-12-6-3/h4-7H2,1-3H3 Key: BULVZWIRKLYCBC-UHFFFAOYAA
SMILES S=P(OCC)(SCSCC)OCC
Properties
Chemical formula	C7H17O2PS3
Molar mass	260.36 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

WikiDoc Resources for Phorate
Articles
Most recent articles on Phorate Most cited articles on Phorate Review articles on Phorate Articles on Phorate in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Phorate Images of Phorate Photos of Phorate Podcasts & MP3s on Phorate Videos on Phorate
Evidence Based Medicine
Cochrane Collaboration on Phorate Bandolier on Phorate TRIP on Phorate
Clinical Trials
Ongoing Trials on Phorate at Clinical Trials.gov Trial results on Phorate Clinical Trials on Phorate at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Phorate NICE Guidance on Phorate NHS PRODIGY Guidance FDA on Phorate CDC on Phorate
Books
Books on Phorate
News
Phorate in the news Be alerted to news on Phorate News trends on Phorate
Commentary
Blogs on Phorate
Definitions
Definitions of Phorate
Patient Resources / Community
Patient resources on Phorate Discussion groups on Phorate Patient Handouts on Phorate Directions to Hospitals Treating Phorate Risk calculators and risk factors for Phorate
Healthcare Provider Resources
Symptoms of Phorate Causes & Risk Factors for Phorate Diagnostic studies for Phorate Treatment of Phorate
Continuing Medical Education (CME)
CME Programs on Phorate
International
Phorate en Espanol Phorate en Francais
Business
Phorate in the Marketplace Patents on Phorate
Experimental / Informatics
List of terms related to Phorate

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Phorate is an organophosphate used as an insecticide and acaricide. At normal conditions, it is a pale yellow mobile liquid poorly soluble in water but readily soluble in organic solvents. It is relatively stable and hydrolyses only at very acidic or basic conditions. It is very toxic both for target organisms and for mammalians including human. It inhibits acetylcholinesterase and pseudocholinesterase.

Phorate is most commonly applied in granular form. It is non-biocumulative and has no residual action. But some metabolites may persist in soil. It also damages some seeds.

Phorate is absorbed readily through all ways. Its toxicity is high. Oral LD₅₀ to rats is 1.1 – 3.2 mg/kg, to mice 3.5 – 6.5 mg/kg (technical phorate). Similar values has been found out to birds.