Oxybuprocaine

220px
Oxybuprocaine
Systematic (IUPAC) name
2-diethylaminoethyl 4-amino-3-butoxy-benzoate
Identifiers
CAS number	99-43-4
ATC code	D04AB03 S01HA02
PubChem	4633
DrugBank	APRD00817
Chemical data
Formula	C17H29ClN2O3
Mol. mass	344.877 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

WikiDoc Resources for Oxybuprocaine
Articles
Most recent articles on Oxybuprocaine Most cited articles on Oxybuprocaine Review articles on Oxybuprocaine Articles on Oxybuprocaine in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Oxybuprocaine Images of Oxybuprocaine Photos of Oxybuprocaine Podcasts & MP3s on Oxybuprocaine Videos on Oxybuprocaine
Evidence Based Medicine
Cochrane Collaboration on Oxybuprocaine Bandolier on Oxybuprocaine TRIP on Oxybuprocaine
Clinical Trials
Ongoing Trials on Oxybuprocaine at Clinical Trials.gov Trial results on Oxybuprocaine Clinical Trials on Oxybuprocaine at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Oxybuprocaine NICE Guidance on Oxybuprocaine NHS PRODIGY Guidance FDA on Oxybuprocaine CDC on Oxybuprocaine
Books
Books on Oxybuprocaine
News
Oxybuprocaine in the news Be alerted to news on Oxybuprocaine News trends on Oxybuprocaine
Commentary
Blogs on Oxybuprocaine
Definitions
Definitions of Oxybuprocaine
Patient Resources / Community
Patient resources on Oxybuprocaine Discussion groups on Oxybuprocaine Patient Handouts on Oxybuprocaine Directions to Hospitals Treating Oxybuprocaine Risk calculators and risk factors for Oxybuprocaine
Healthcare Provider Resources
Symptoms of Oxybuprocaine Causes & Risk Factors for Oxybuprocaine Diagnostic studies for Oxybuprocaine Treatment of Oxybuprocaine
Continuing Medical Education (CME)
CME Programs on Oxybuprocaine
International
Oxybuprocaine en Espanol Oxybuprocaine en Francais
Business
Oxybuprocaine in the Marketplace Patents on Oxybuprocaine
Experimental / Informatics
List of terms related to Oxybuprocaine

Overview

Oxybuprocaine is the name of a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine is sold by Novartis under the brand names Novesine or Novesin.

Where oxybuprocaine is used specifically

• In ophthalmology in order to numb the surface of the eye (the outermost layers of the cornea and conjunctiva) for the following purposes:
  • In order to perform a contact/applanation tonometry.
  • In order to remove small foreign objects from the uppermost layer of the cornea or conjunctiva.
• In otolaryngology for numbing the mucous membranes of the nostrils.

Topical anesthetics in general

Oxybuprocaine like any other topical anesthetic used in the eye (like for example tetracaine, proxymetacaine and proparacaine) can cause irreversible corneal damage and even complete destruction of the cornea when used excessively (excessive use means several times a day during several days or even weeks).

See also

• Topical anesthetic

de:Oxybuprocain