Novel human coronavirus infection historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]

Overview

The virus first emerged in the Middle East, and was discovered on September 2012 in a Qatari patient who had recently traveled to Saudi Arabia.[1] Virologist Ron Fouchier has speculated that the virus might originate from bats.[2]

Historical Perspective

The virus first emerged in the Middle East, and was discovered on September 2012 in a Qatari patient who had recently traveled to Saudi Arabia.[3] He is being treated for the respiratory disease, which has led to renal failure.[4] The first known case was a Saudi Arabian who died in early 2012. The World Health Organisation (WHO) announced that it is engaged in further characterizing the novel coronavirus and that it has immediately alerted all its member states about the virus and has been leading the coordination and providing guidance to health authorities and technical health agencies.[5] Virologist Ron Fouchier has speculated that the virus might originate from bats.[6]

Saudi Arabia's Ministry of Health was concerned that the virus might affect the October 2012 Hajj, the Islamic pilgrimage to Mecca, as Muslims making the Hajj may have been infected.[7]

Following the high-profile publicity of SARS outbreaks, there has been a renewed interest in coronaviruses in the field of virology. For many years, scientists knew only about the existence of two human coronaviruses (HCoV-229E and HCoV-OC43). The discovery of SARS-CoV added another human coronavirus to the list. By the end of 2004, three independent research labs reported the discovery of a fourth human coronavirus. It has been named NL63, NL or the New Haven coronavirus by the different research groups.[8] The naming of this fourth coronavirus is still a controversial issue, because the three labs are still battling over who actually discovered the virus first and hence earns the right to name the virus. Early in 2005, a research team at the University of Hong Kong reported finding a fifth human coronavirus in two pneumonia patients, and subsequently named it HKU1.

References

  1. Nebehay, Stephanie (26 September 2012). "WHO issues guidance on new virus, gears up for haj". Reuters. Retrieved 27 September 2012.
  2. Doucleff, Michaeleen (28 September 2012). "Holy Bat Virus! Genome Hints At Origin Of SARS-Like Virus". NPR. Retrieved 29 September 2012.
  3. Nebehay, Stephanie (26 September 2012). "WHO issues guidance on new virus, gears up for haj". Reuters. Retrieved 27 September 2012.
  4. Falco, Miriam (24 September 2012). "New SARS-like virus poses medical mystery". CNN. Retrieved 27 September 2012.
  5. "Novel coronavirus infection". World Health Organisation. 25 September 2012. Retrieved 27 September 2012.
  6. Doucleff, Michaeleen (28 September 2012). "Holy Bat Virus! Genome Hints At Origin Of SARS-Like Virus". NPR. Retrieved 29 September 2012.
  7. Moisse, Katie (27 September 2012). "Saudi Health Officials Brace for Hajj Pilgrimage to Mecca". ABC News. Retrieved 27 September 2012.
  8. van der Hoek L, Pyrc K, Jebbink MF; et al. (2004). "Identification of a new human coronavirus". Nat Med. 10 (4): 368&ndash, 73. doi:10.1038/nm1024.


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