Novel human coronavirus infection case definitions

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]

Case Definitions

In accordance with new data regarding geographic spread of the virus, case definitions have been updated.

Patient Under Investigation

• A person with an acute respiratory infection, which may include fever (≥ 38°C , 100.4°F) and cough.

AND

• Suspicion of pulmonary parenchymal disease (e.g., pneumonia or acute respiratory distress syndrome based on clinical or radiological evidence of consolidation).

AND

• Travel to or residence in the Arabian Peninsula or neighboring countries where infection with novel coronavirus has recently been reported and where transmission could have occurred.

AND

• Not already explained by any other infection or etiology, including all clinically indicated tests for community-acquired pneumonia according to local management guidelines.

Close contacts of laboratory confirmed cases may also be considered PUIs. CDC requests that state and local health departments report PUIs for novel coronavirus to CDC.

Probable Case

• A person fitting the definition above of a patient under investigation with clinical, radiological, or histopathological evidence of pulmonary parenchyma disease (e.g. pneumonia or ARDS) but no possibility of laboratory confirmation either because the patient or samples are not available or there is no testing available for other respiratory infections.

AND

• Close contact with a laboratory confirmed case.

AND

• Not already explained by any other infection or etiology, including all clinically indicated tests for community-acquired pneumonia according to local management guidelines.

Confirmed Case

• A person with laboratory confirmation of infection with the novel coronavirus.

References

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