Mycobacterium houstonense
| Mycobacterium houstonense | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Scientific classification | ||||||||||||||
| ||||||||||||||
| Binomial name | ||||||||||||||
| Mycobacterium houstonense Schinsky et al. 2004, ATCC 49403 |
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
Mycobacterium houstonense
Mycobacterium houstonense is a member of the Mycobacterium fortuitum third biovariant complex. They are rapidly growing ubiquitous environmental organisms that normally inhabit soil, dust and water. These organisms frequently are human pathogens that cause a wide spectrum of clinically significant disease. It is important for practitioners to be aware of these organisms as possible etiological agents, as they are resistant to most first-line anti-tuberculous agents.
- Etymology: houstonense pertaining to Houston, TX, USA, where the first isolate of the M. fortuitum third biovariant (sorbitol-positive) was identified.
Description
Microscopy
- The organisms are acid-fast, Gram-positive, pleomorphic bacilli. Long filamentous forms are often observed, but the organisms have no spores or capsules.
Colony characteristics
- Colonies are mucoid, convex, round and entire-edged and do not demonstrate aerial hyphae.
- Colonies are white to slightly beige, small-diameter (approx. 1 mm) colonies after incubation on heart infusion agar with 5 % (v/v) rabbit blood for 2 days at 35 °C
Physiology
- Growth on Löwenstein–Jensen medium at 35 and 42 °C in less than 7 days
- Growth occurs on 5 % NaCl and on MacConkey's agar without crystal violet at 28 °C.
- Semi-quantitative catalase of both isolates is weakly reactive (<45 mm).
- The isolate has arylsulfatase activity by 3 days, utilize acetamide, reduce nitrate, exhibit iron uptake and produce urease and thermostable catalase.
- It does not utilize citrate or grow in lysozyme.
Differential characteristics
- The nearest phylogenetic neighbours, according to 16S rRNA gene sequence similarity, are M. fortuitum ATCC 6841T and M. senegalense ATCC 35796T.
Pathogenesis
- Reported infections include skin and soft-tissue abscesses with associated osteomyelitis, bacteraemia, endocarditis, keratitis, lymphadenitis, peritonitis, post-surgical infections, pulmonary infections and disseminated disease. Involvement of the central nervous system is rare, but meningitis may develop after trauma or surgery. The immunocompromised patient is at special risk for developing severe diseases, especially catheter-related infection with bacteraemia.
Type Strain
- The type strain, which was isolated from a face wound, is W5198T =ATCC 49403T =DSM 44676T.
References
- Schinsky et al. 2004. Taxonomic variation in the Mycobacterium fortuitum third biovariant complex: description of Mycobacterium boenickei sp. nov., Mycobacterium houstonense sp. nov., Mycobacterium neworleansense sp. nov. and Mycobacterium brisbanense sp. nov. and recognition of Mycobacterium porcinum from human clinical isolates. Int. J. Syst. Evol. Microbiol., 2004, 54, 1653-1667.
</br> de:Mycobacterium houstonense nl:Mycobacterium houstonense
WikiDoc Research Resources for Mycobacterium houstonense | |
|---|---|
| Articles on Mycobacterium houstonense | Most recent articles on Mycobacterium houstonense • Most cited articles on Mycobacterium houstonense • Review articles on Mycobacterium houstonense • Articles on Mycobacterium houstonense in N Eng J Med, Lancet, BMJ |
| Media (Slides, Video, Images, MP3) on Mycobacterium houstonense | Powerpoint slides on Mycobacterium houstonense • Images of Mycobacterium houstonense • Photos of Mycobacterium houstonense • Podcasts & MP3s on Mycobacterium houstonense • Videos on Mycobacterium houstonense |
| Evidence Based Medicine Regarding Mycobacterium houstonense | AND (Cochrane Database Syst Rev[http://worldselectshop.com/?id=9361 Cochrane Collaboration on Mycobacterium houstonense • Bandolier on Mycobacterium houstonense • TRIP on Mycobacterium houstonense |
| Cost Effectiveness of Mycobacterium houstonense | AND (Cost effectiveness) |
| group5 = Clinical Trials Involving Mycobacterium houstonense | list5 = Ongoing Trials on Mycobacterium houstonense at Clinical Trials.gov • Trial results on Mycobacterium houstonense • Clinical Trials on Mycobacterium houstonense at Google
| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding Mycobacterium houstonense
| list6 = US National Guidelines Clearinghouse on Mycobacterium houstonense • NICE Guidance on Mycobacterium houstonense • NHS PRODIGY Guidance • FDA on Mycobacterium houstonense • CDC on Mycobacterium houstonense
| group7 = Textbook Information on Mycobacterium houstonense
| list7 = Books and Textbook Information on Mycobacterium houstonense
| group8 = Pharmacology Resources on Mycobacterium houstonense
| list8 =
AND (Dose)}} Dosing of Mycobacterium houstonense • AND (drug interactions)}} Drug interactions with Mycobacterium houstonense • AND (side effects)}} Side effects of Mycobacterium houstonense • AND (Allergy)}} Allergic reactions to Mycobacterium houstonense • AND (overdose)}} Overdose information on Mycobacterium houstonense • AND (carcinogenicity)}} Carcinogenicity information on Mycobacterium houstonense • AND (pregnancy)}} Mycobacterium houstonense in pregnancy • AND (pharmacokinetics)}} Pharmacokinetics of Mycobacterium houstonense •
| group9 = Genetics, Pharmacogenomics, and Proteinomics of Mycobacterium houstonense
| list9 =
AND (pharmacogenomics)}} Genetics of Mycobacterium houstonense • AND (pharmacogenomics)}} Pharmacogenomics of Mycobacterium houstonense • AND (proteomics)}} Proteomics of Mycobacterium houstonense
| group10 = Newstories on Mycobacterium houstonense
| list10 = Mycobacterium houstonense in the news • Be alerted to news on Mycobacterium houstonense • News trends on Mycobacterium houstonense</small>
| group11 = Commentary on Mycobacterium houstonense
| list11 =
Blogs on Mycobacterium houstonense
| group12 = Patient Resources on Mycobacterium houstonense | list12 = Patient resources on Mycobacterium houstonense • Discussion groups on Mycobacterium houstonense • Patient Handouts on Mycobacterium houstonense • Directions to Hospitals Treating Mycobacterium houstonense • Risk calculators and risk factors for Mycobacterium houstonense
| group13 = Healthcare Provider Resources on Mycobacterium houstonense
| list13 =
Symptoms of Mycobacterium houstonense • Causes & Risk Factors for Mycobacterium houstonense • Diagnostic studies for Mycobacterium houstonense • Treatment of Mycobacterium houstonense
| group14 = Continuing Medical Education (CME) Programs on Mycobacterium houstonense | list14 = CME Programs on Mycobacterium houstonense
| group15 = International Resources on Mycobacterium houstonense | list15 = Mycobacterium houstonense en Espanol • Mycobacterium houstonense en Francais
| group16 = Business Resources on Mycobacterium houstonense | list16 = Mycobacterium houstonense in the Marketplace • Patents on Mycobacterium houstonense
| group17 = Informatics Resources on Mycobacterium houstonense | list17 = List of terms related to Mycobacterium houstonense
}}
Table of Contents In Alphabetical Order | By Individual Diseases | Signs and Symptoms | Physical Examination | Lab Tests | Drugs
Editor Tools Become an Editor | Editors Help Menu | Create a Page | Edit a Page | Upload a Picture or File | Printable version | Permanent link | Maintain Pages | What Pages Link HereThere is no pharmaceutical or device industry support for this site and we need your viewer supported Donations | Editorial Board | Governance | Licensing | Disclaimers | Avoid Plagiarism | Policies
