Multiple endocrine neoplasia type 2 MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [4]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [5]

Overview

MRI scan may be helpful in the diagnosis of multiple endocrine neoplasia type 2. Findings on MRI scan suggestive of multiple endocrine neoplasia type 2 include intermediate to low signal at T1 and hyperintense signal at T2 suggesting parathyroid hyperplasia.

MRI

Parathyroid Carcinoma

  • T1
  • T2
  • Since most lesions demonstrate high T2 signal intensity, the addition of contrast for MRI scanning does not significantly increase detection.

Pheochromocytoma

  • MRI is the most sensitive modality for identification of pheochromocytomas, and is particularly useful in cases of extra-adrenal location. The overall sensitivity is said to be 98%.[3][1]
  • T1
  • T2
  • T1 C+ (Gd)
  • Heterogenous enhancement
  • Enhancement is prolonged, persisting for as long as 50 minutes[4]

References

  1. 1.0 1.1 "Radiopedia 2015 Parathyroid adenoma [Dr Bruno Di Muzio and Dr Yuranga Weerakkody]".
  2. Johnson NA, Tublin ME, Ogilvie JB (2007). "Parathyroid imaging: technique and role in the preoperative evaluation of primary hyperparathyroidism". AJR Am J Roentgenol. 188 (6): 1706–15. doi:10.2214/AJR.06.0938. PMID 17515397.
  3. Blake, Michael (2009). Adrenal imaging. Totowa, NJ: Humana Press. ISBN 193411586X.
  4. Reiser, Maximilian (2008). Magnetic resonance tomography. Berlin: Springer. ISBN 354029354X.
  5. Image courtesy of Dr Hani Al Salami. Radiopaedia (original file[1]).Creative Commons BY-SA-NC
  6. Image courtesy of Dr Frank Gaillard. Radiopaedia (original file[2]).Creative Commons BY-SA-NC
  7. Image courtesy of Dr Frank Gaillard. Radiopaedia (original file[3]).Creative Commons BY-SA-NC


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