Macrocytosis
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| Macrocytosis Classification and external resources | |
| ICD-10 | D75.8 |
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| ICD-9 | 289.89 |
| DiseasesDB | 7688 |
| eMedicine | med/1381 |
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US National Guidelines Clearinghouse on Macrocytosis
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Macrocytosis is the enlargement of red blood cells with near-constant haemoglobin concentration, and is defined by a mean corpuscular volume (MCV) of greater than 100 femtolitres (the precise criterion varies between laboratories).
Causes
Most commonly this etiology is bone marrow dysplasia primary to alcohol abuse. Other causes may include:
- Vitamin B12 or folate deficiency
- hypothyroidism
- reticulocytosis
- liver disease
- myeloproliferative disease
Complications
No complications arise from macrocytosis itself and a prognosis will be determined from its aetiology.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
