Lymphadenopathy history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2], Raviteja Guddeti, M.B.B.S. [3]Delband Yekta Moazami, M.D.[4] Ogechukwu Hannah Nnabude, MD
Overview
Physical examination and history are the basis of time and cost-effective diagnosis of lymphadenopathy. The evident occurrence and associated localized anterior cervical adenopathy of strep pharyngitis need far less clinical brainpower than generalized adenopathy secondary to sarcoidosis or Gaucher disease. The hallmark of lymphadenopathy is swollen lymph node. A positive history of a lump in the neck, red, tender skin over lymph node, and swollen, tender, or hard lymph nodes is suggestive of lymphadenopathy. The most common symptoms of lymphadenopathy include a lump in neck or affected part and constitutional symptoms like fatigue, fever, malaise, flu-like illness, nausea and vomiting, night sweats, weight loss, and cachexia.
History and Symptoms
History
A directed history should be obtained to ascertain:[1]
- Constitutional symptoms like night sweats, fever, weight loss suggesting tuberculosis, Hodgkin's lymphoma, other malignancy[2]
- Associated signs and symptoms for suggesting infections or malignancy
- Use of drugs causing lymphadenopathy
- Travel to endemic areas
- High-risk behavior- high-risk sexual behavior, I.V drug abuse
Patients with lymphadenopathy may have a positive history of:
- Lump in the neck (e.g. in tumors, sarcoidosis).
- Red, tender skin over lymph node.
- Swollen, tender, or hard lymph nodes.
Common Symptoms
Common symptoms of lymphadenopathy include:
- Lump in the neck
- Red, tender skin over lymph node
- Swollen, tender, or hard lymph nodes
- Constituitional symptoms like:[3]
- Fatigue
- Fever
- Malaise
- Flu- like illness
- Nausea and vomiting
- Night sweats
- Weight loss and
- Cachexia
References
- ↑ Freeman AM, Matto P. PMID 30020622. Missing or empty
|title=(help) - ↑ Bazemore AW, Smucker DR (December 2002). "Lymphadenopathy and malignancy". Am Fam Physician. 66 (11): 2103–10. PMID 12484692.
- ↑ Mohseni S, Shojaiefard A, Khorgami Z, Alinejad S, Ghorbani A, Ghafouri A (2014). "Peripheral lymphadenopathy: approach and diagnostic tools". Iran J Med Sci. 39 (2 Suppl): 158–70. PMC 3993046. PMID 24753638.