Logopenic progressive aphasia

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Logopenic progressive aphasia (LPA) is a form of primary progressive aphasia characterized by slow speech and impaired syntactic comprehension and naming. It is similar to Wernicke's aphasia and is associated with atrophy to the left posterior temporal cortex and inferior parietal lobule. It is suspected that an atypical form of Alzheimer's disease is the most common cause of logopenic progressive aphasia.

References

• Gorno-Tempini ML, Dronkers NF, Rankin KP, Ogar JM, Phengrasamy L, Rosen HJ, Johnson JK, Weiner MW, Miller BL. (2004) "Cognition and anatomy in three variants of primary progressive aphasia." Ann Neurol. 55(3):335-46.