| Pathology: hematology (primarily D50-D77, 280-289) |
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RBCs/anemia/
hemoglobinopathy
(Myeloid) | nutritional anemia: Iron deficiency anemia, Plummer-Vinson syndrome, Megaloblastic anemia (Pernicious anemia)
hereditary hemolytic anemia: enzyme disorders (G6PD Deficiency, Pyruvate kinase deficiency,Triosephosphate isomerase deficiency), Thalassemia, Sickle-cell disease/trait, Hereditary spherocytosis, Hereditary elliptocytosis, Hereditary stomatocytosis
acquired hemolytic anemia: Autoimmune (Warm), HUS, MAHA, PNH, PCH
aplastic anemia: Acquired PRCA, Diamond-Blackfan anemia, Fanconi anemia • Sideroblastic anemia |
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Coagulation/platelets
(Myeloid) | coagulopathy: DIC (Congenital afibrinogenemia, Purpura fulminans) • Hemophilia (A/VII, B/IX, C/XI, XIII) • Von Willebrand disease
Purpura: Henoch-Schönlein, ITP (Evans syndrome), TTP
primary hypercoagulable state: Protein C deficiency -
Protein S deficiency - Antithrombin III deficiency - Factor V Leiden - Activated protein C resistance - Antiphospholipid syndrome
other hemorrhagic conditions: Bernard-Soulier syndrome - Glanzmann's thrombasthenia - Grey platelet syndrome - May Hegglin anomaly
Essential thrombocytosis - Thrombocytopenia |
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Monocytes/Macrophages
(Myeloid) | WHO-I histiocytosis (Langerhans cell histiocytosis)
WHO-II/non-Langerhans-cell histiocytosis (Juvenile xanthogranuloma, Hemophagocytic lymphohistiocytosis)
WHO-III/malignant histiocytic disorders (Acute monocytic leukemia, Malignant histiocytosis, Erdheim-Chester disease)
-cytosis: Monocytosis
-penia: Monocytopenia |
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Granulocytes
(Myeloid) | -cytosis: granulocytosis (Neutrophilia, Eosinophilia, Basophilia)
-penia: Granulocytopenia/agranulocytosis (Neutropenia, Kostmann syndrome) |
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| Other/general myeloid | Chronic granulomatous disease |
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| Lymphoid | -cytosis: Lymphocytosis
-penia: Lymphopenia |
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| Other | Asplenia/hyposplenism - Methemoglobinemia - Pancytopenia |
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| See also hematological malignancy and immune disorders |
