Hemoglobinuria
| Hemoglobinuria | |
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|---|---|
| ICD-10 | R82.3 |
| ICD-9 | 283.2, 791.2 |
| DiseasesDB | 19635 |
| MeSH | D006456 |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Hemoglobinuria is a condition in which the oxygen transport protein hemoglobin is found in abnormally high concentrations in the urine. The condition is often associated with hemolytic anemia, in which red blood cells are destroyed, thereby increasing levels of free plasma hemoglobin. The excess hemoglobin is filtered by the kidneys, which release it into the urine, giving urine a red colour.
Causes
In alphabetical order: [1] [2]
- Acute glomerulonephritis
- Burns
- Kidney cancer
- Malaria
- Paroxysmal nocturnal hemoglobinuria
- Hemolytic-uremic syndrome (HUS)
- Pyelonephritis
- Sickle cell anemia
- Transfusion immune reaction
- Thrombotic thrombocytopenic purpura (TTP)
- Tuberculosis of the urinary tract
- Exertional hemoglobinuria
Complications
Hemoglobinuria can lead to acute tubular necrosis and is a common cause of death of multi-traumatic patients recovering on the ICU.
References
- ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
- ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X
See also
Abnormal clinical and laboratory findings (R70-R94, 790-796) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Blood test | |||||||||
| Urine test |
| ||||||||
| Other | Abnormal basal metabolic rate - Latent tuberculosis | ||||||||
Symptoms and signs: circulatory (R00–R03, 785) | |||||||
|---|---|---|---|---|---|---|---|
| Cardiovascular |
| ||||||
| Myeloid/blood |
| ||||||
Symptoms and signs: respiratory system (R04–R07, 786) | |
|---|---|
| Hemorrhage | * Epistaxis |
| Abnormalities of breathing | ; Respiratory sounds: |
| Other | * Asphyxia |
| Chest, general | * Chest pain |
Symptoms and signs: skin and subcutaneous tissue (R20-R23, 782) | |
|---|---|
| Disturbances of skin sensation | Hypoesthesia - Paresthesia - Hyperesthesia |
| Other | Rash - Cyanosis - Pallor - Flushing - Petechia - Desquamation - Induration - Diaphoresis |
Symptoms and signs: nervous and musculoskeletal systems (R25-R29, 781) | |
|---|---|
| Abnormal involuntary movements (see also movement disorders) | Tremor - Spasm - Fasciculation - Athetosis |
| Gait abnormality | Scissor gait - Antalgic gait - Cerebellar ataxia - Festinating gait - Pigeon gait - Propulsive gait - Steppage gait - Stomping gait - Spastic gait - Myopathic gait - Magnetic gait - Trendelenburg gait |
| Lack of coordination | Ataxia (Cerebellar ataxia, Sensory ataxia) - Dysmetria - Dysdiadochokinesia - Hypotonia |
| Other | Tetany - Meningism - Hyperreflexia - Opisthotonus - Abnormal posturing - Hemispatial neglect |
Symptoms and signs: urinary system (R30-R39, 788) | |
|---|---|
| General | Renal colic - Dysuria - Vesical tenesmus - Urinary incontinence - Urinary retention - Oliguria - Polyuria - Nocturia - Extravasation of urine - Extrarenal uremia |
Symptoms and signs: cognition, perception, emotional state and behaviour (R40-R46, 780-781) | |
|---|---|
| General | Anxiety - Somnolence - Coma - Amnesia (Anterograde amnesia, Retrograde amnesia) - Dizziness/Vertigo |
| Olfaction | Anosmia - Parosmia |
| Taste | Ageusia - Parageusia |
Symptoms and signs: Speech and voice (R47-R49, 784) | |
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| Aphasia/Dysphasia | Expressive aphasia - Receptive aphasia - Conduction aphasia |
| Other speech disturbances | Dysarthria - Schizophasia |
| Symbolic dysfunctions | Dyslexia - Alexia - Agnosia (Prosopagnosia) - Apraxia - Acalculia - Agraphia |
| Voice disturbances | Dysphonia - Aphonia |
Symptoms and signs: general (R50-R69, 780-789) | |
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| General | Fever (Hyperpyrexia) - Headache - Chronic pain - Malaise/Fatigue (Asthenia, Debility) - Fainting (Vasovagal syncope) - Febrile seizure - Shock (Cardiogenic shock) - Lymphadenopathy - Edema (Peripheral edema, Anasarca) - Hyperhidrosis (Sleep hyperhidrosis) - Delayed milestone - Failure to thrive - Short stature (Idiopathic) - food and fluid intake (Anorexia, Polydipsia, Polyphagia) - Cachexia - Xerostomia - Clubbing - Tenderness |
Symptoms and signs: Symptoms concerning nutrition, metabolism and development (R62–R64, 783) | |
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| Ingestion/Weight | |
| Growth | Delayed milestone • Failure to thrive • Short stature (e.g., Idiopathic) |
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