Liposarcoma history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]
Overview
Liposarcoma usually presents as a painless mass. The most common location of a liposarcoma is the lower extremities. Patients with retroperitoneal liposarcoma remain asymptomatic until the mass invades adjacent structures, which may cause pain or obstructive symptoms. Esophageal liposarcoma may cause dysphagia, vomiting, cough, gastrointestinal bleeding, and hoarseness. Symptoms of gastrointestinal bleeding are common manifestations of liposarcoma located in the small bowel and the colon. Symptoms of mediastinal liposarcoma include dyspnea, cough, chest pain, and weight loss.
History and symptoms
- Symptoms of liposarcoma will depend on the location of the tumor.
- Liposarcoma located in the deep soft tissue of the extremities presents as a painless mass that grows slowly over several months.
- Superficial liposarcomas are commonly located in the lower extremities, especially in the femoral and popliteal regions.
Retroperitoneal Liposarcoma
- The majority of patients with retroperitoneal liposarcoma remain asymptomatic until the tumor grows to a considerable size (10 - 20 cm).
- Common symptoms of retroperitoneal liposarcoma include weight loss and abdominal pain.[1]
- The tumor may compress adjacent organs and vascular structures to cause pain or obstructive symptoms.[2]
- The kidneys or ureters may also be involved, which may result in urologic symptoms, such as oliguria, or renal failure.
Esophageal Liposarcoma
- Esophageal liposarcoma is extremely rare.[3]
- Esophageal liposarcoma may cause difficulty swallowing, vomiting, cough, gastrointestinal bleeding, and hoarseness.[3]
Bowel Liposarcoma
- Symptoms of gastrointestinal bleeding are common manifestations of liposarcoma located in the small bowel and the colon.[4]
Mediastinal Liposarcoma
- Mediastinal liposarcomas are rare.
- Symptoms include difficulty breathing, cough, chest pain, and weight loss.[5][6]
- Difficulty swallowing[6]
References
- ↑ Grasso, Emanuele; Marino, Fabio; Bottalico, Michele; Simone, Michele (2014). "A Case of Myxoid Liposarcoma of the Retroperitoneum: A Challenging Tumour for Diagnosis and Treatment". Case Reports in Surgery. 2014: 1–4. doi:10.1155/2014/572805. ISSN 2090-6900.
- ↑ McGrath, Patrick C. (1994). "Retroperitoneal sarcomas". Seminars in Surgical Oncology. 10 (5): 364–368. doi:10.1002/ssu.2980100509. ISSN 8756-0437.
- ↑ 3.0 3.1 Dowli, A.; Mattar, A.; Mashimo, H.; Huang, Q.; Cohen, D.; Fisichella, P. M.; Lebenthal, A. (2014). "A Pedunculated Giant Esophageal Liposarcoma: a Case Report and Literature Review". Journal of Gastrointestinal Surgery. doi:10.1007/s11605-014-2628-8. ISSN 1091-255X.
- ↑ Simon Nennstiel, Martin Mollenhauer, Christoph Schlag, Valentin Becker, Bruno Neu, Norbert Huser, Ralf Gertler, Roland M. Schmid & Stefan von Delius (2014). "Small bowel pleomorphic liposarcoma: a rare cause of gastrointestinal bleeding". Case reports in gastrointestinal medicine. 2014: 391871. doi:10.1155/2014/391871. PMID 25161780.
- ↑ Fukuhara, Shinichi; Dimitrova, Kamellia R; Geller, Charles M; Hoffman, Darryl M; Ko, Wilson; Tranbaugh, Robert F (2014). "Progressive dyspnea in patient with large mediastinal mass". Journal of Cardiothoracic Surgery. 9 (1): 6. doi:10.1186/1749-8090-9-6. ISSN 1749-8090.
- ↑ 6.0 6.1 Chun Zhao, Fangbiao Zhang, Xiangyan Zhang, Shaosong Tu, Zhijun Wu, Xia Li, Yingming Xiang, Chunhui Zheng & Qinghui Zeng (2016). "Recurrent primary mediastinal liposarcoma: A case report". Oncology letters. 11 (6): 3782–3784. doi:10.3892/ol.2016.4453. PMID 27313694. Unknown parameter
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