Lassa fever other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Other diagnostic tests to confirm the diagnosis of lassa fever include reverse transcription-polymerase chain reaction (RT-PCR) and immunohistochemistry using either skin, tissue or liver tissue.
Other Diagnostic Studies
Listed below are some of the diagnostic test used to confirm Lassa fever.[1]
| Diagnostic Test | Samples required | Preparation & Storage | Detects |
| Polymerase Chain Reaction (PCR) | Serum or plasma or tissues (fresh frozen) | Freeze or refrigerate | Detects DNA, RNA (genetic material) from virus. |
| Immunohistochemistry | Liver biopsy from fatal cases | Fix in formalin and store or transport in room temperature | Detects viral antigen in cells. |
| Immunohistochemistry | Tissue biopsy from fatal cases | Fix in formalin and store or transport in room temperature | Detects viral antigen in cells |
| Immunohistochemistry | Skin biopsy from fatal cases | Fix in formalin and store or transport in room temperature | Detects viral antigen in cells |
Data from the Centers for Disease Control and Prevention
References