Hydronephrosis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [2]

Overview

Some patients with hydronephrosis may have elevated WBC count, serum creatinine, BUN, potassium levels and pyuria.

Patients with hydronephrosis may show following findings on laboratory tests. These include:^[1]^[2]^[3]^[4]^[5]

Complete blood count (CBC):
- Elevated WBC count may indicate the presence of infection.
- Anemia
Elevated serum creatinine
- Suggestive of bilateral obstruction or unilateral obstruction and an underlying kidney disease
Anuria and acute kidney injury (AKI)
Elevated BUN
Elevated serum potassium levels (hyperkalemia)
Urinalysis and cultures: It may show red blood cells and white blood cells indicating hematuria and pyuria.
- Hematuria is commonly caused by stones or due to tumors.
- Pyuria indicates an evidence of infection.
- Urinary cultures are helpful in identifying infection.

↑ Onuigbo MA (October 2009). "Symptomatic uraemia from bilateral obstructive uropathy secondary to metastatic urinary bladder cancer showing only unilateral hydronephrosis: a case report". NDT Plus. 2 (5): 387–9. doi:10.1093/ndtplus/sfp093. PMC 4421382. PMID 25949352.
↑ Batlle DC, Arruda JA, Kurtzman NA (February 1981). "Hyperkalemic distal renal tubular acidosis associated with obstructive uropathy". N. Engl. J. Med. 304 (7): 373–80. doi:10.1056/NEJM198102123040701. PMID 7453754.
↑ Maletz R, Berman D, Peelle K, Bernard D (December 1993). "Reflex anuria and uremia from unilateral ureteral obstruction". Am. J. Kidney Dis. 22 (6): 870–3. PMID 8250035.
↑ Hayashi K, Horikoshi S, Hirano K, Shirato I, Tomino Y (October 1996). "A case of reflex anuria and uremia related to a unilateral ureteral stone". Nihon Jinzo Gakkai Shi. 38 (10): 460–2. PMID 8940828.
↑ Hull JD, Kumar S, Pletka PG (February 1980). "Reflex anuria from unilateral ureteral obstruction". J. Urol. 123 (2): 265–6. PMID 7354536.