Hexetidine

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Hexetidine
Systematic (IUPAC) name
1,3-bis(2-ethylhexyl)-5-methyl-1,3-diazinan-5-amine
Identifiers
CAS number	141-94-6
ATC code	A01AB12
PubChem	3607
Chemical data
Formula	C21H45N3
Mol. mass	339.602 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	Topical (mouthwash)

Hexetidine (Latin: Hexetidinum) is an anti-bacterial and anti-fungal agent commonly used in both veterinary and human medicine. It is a local anesthetic, astringent and deodorant and has antiplaque effects.

Hexetidine is the medicinal ingredient in Sterisol, which is labelled for "the symptomatic treatment of 'strep' throat, tonsillitis, pharyngitis, laryngitis, gingivitis, ulcerative stomatitis, oral thrush and Vincent's angina; postoperative hygiene following tonsillectomy, throat or oral surgery."

In the UK, Hexetidine is the active ingredient in the medicated mouthwash branded Oraldene. This is produced by Pfizer. Oraldene mouthwash contains 0.1g/100ml of Hexetidine. In some Eastern European countries, the gargle solution Hexoral (by Pfizer) also contains Hexetidine as its active compound. Hexetidine can also be found in the mouthwash Bactidol™ (by Pfizer) which is sold in many Asian countries.

External links

• European Agency for the Evaluation of Medicinal Products overview of the medicinal properties
• netDoctor