Heartburn risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: José Eduardo Riceto Loyola Junior, M.D.[2]

Overview

Common risk factors in the development of heartburn as a consequence of gastroesophageal reflux disease (GERD) are obesity, increasing age, smoking, hiatal hernia, white bread, chocolate, mint, cinnamon, carbonated beverages, fatty foods, alcohol, wine and beer.
Less common risk factors include certain genetic changes.

Common Heartburn Risk Factors

List of risk factors for heartburn[3][1]
Risk Factors:
Obesity
Age
Smoking
Hiatal Hernia
Dietary Risk Factors
White bread
Chocolate
Mint
Cinnamon
Carbonated beverages
Fatty foods
Alcohol - Wine and ber
Genetic Risk Factors
C allele in FOX1 rs9936833 - ↑ reflux symptoms
A allele in MHC rs9257809 - ↑ reflux symptoms
rs10419226 (chr 19) - ↑GERD symptoms
rs2687201 (chr 3) ↑GERD symptoms
ABHD10, RNF7, RASGRF2, BTF3P7, C8orf4, GLDC, and ADAMTS17

References

  1. 1.0 1.1 Argyrou A, Legaki E, Koutserimpas C, Gazouli M, Papaconstantinou I, Gkiokas G; et al. (2018). "Risk factors for gastroesophageal reflux disease and analysis of genetic contributors". World J Clin Cases. 6 (8): 176–182. doi:10.12998/wjcc.v6.i8.176. PMC 6107529. PMID 30148145.
  2. Oliveria SA, Christos PJ, Talley NJ, Dannenberg AJ (1999). "Heartburn risk factors, knowledge, and prevention strategies: a population-based survey of individuals with heartburn". Arch Intern Med. 159 (14): 1592–8. doi:10.1001/archinte.159.14.1592. PMID 10421282.
  3. Raibrown A, Giblin LJ, Boyd LD, Perry K (2017). "Gastroesophageal Reflux Disease Symptom Screening in a Dental Setting". J Dent Hyg. 91 (1): 44–48. PMID 29118150.